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Neuroendocrine Cancer diagnosis

If your health care provider believes you may have an NET, you will need certain exams and tests to be sure.

You should expect to be asked questions about your health history, your symptoms, risk factors and family history of disease. Understanding your background will help your provider make a diagnosis.

The first step is for the doctor to take a complete medical history to check for risk factors and symptoms.

  • Blood and Urine Tests

    Your doctor may collect blood and urine samples to check for abnormal levels of hormones and other indicators of NETs. We might also look for specific biomarkers or other signs of cancer.

  • Imaging Tests

    • Computer tomography (CT) scan. CT scans are most useful for detecting the stage of the cancer being diagnosed. The scan’s results tell your doctor if the cancer has spread to your lungs, liver or other organs.
    • Magnetic resonance imaging (MRI) scan. Typically, MRI scans are the best test for outlining a bone tumor and are also helpful for looking at the brain and spinal cord. MRI scans take longer than CT scans — usually around an hour.
    • Gallium 68 dotatate or Copper 64 dotatate positron emission tomography (PET). This specialized and highly sensitive PET scan looks for neuroendocrine tumors.
  • Biopsy

    A biopsy removes tissue or cells that are checked by a pathologist under a microscope. Results from a biopsy help determine if abnormal cells are cancerous. Your doctor may perform this procedure in a variety of ways, including bronchoscopy, mediastinoscopy and needle biopsy.

    A biopsy may be performed with imaging guidance. Ask your provider about your specific type of biopsy to learn more.

  • Test Results

    Patients will be contacted after a biopsy by a Markey team member to review results. Further management will be recommended at that time.

  • Second Opinions

    When you are diagnosed with neuroendocrine cancer, it is common to feel a sense of urgency around starting treatment. However, in most cases, there is time to do the needed research to ensure that your diagnosis is correct. That may include getting a second opinion.

    Our team of experts works together to diagnose, treat and prevent neuroendocrine cancer, with a focus on individualized patient care.

    Markey is among the best cancer centers in the nation, according to U.S. News & World Report, when it comes to advanced treatment options, survival rates and experienced providers. As the one and only NCI-designated cancer program in Kentucky, Markey is able to serve many patients each year with rare and common cancers, including neuroendocrine cancer.

    Our specialized team is happy to work with your doctors and communicate to ensure confidence in your diagnosis.

  • Should I get a second opinion?

    A second opinion can help to ensure that you will be getting the latest and most effective therapy for treating neuroendocrine cancer. The following are common reasons for seeking a second opinion after your initial diagnosis:

    • You are having difficulty understanding your diagnosis.
    • A dedicated team specialized in your cancer type may not be available in your area.
    • There may be uncertainty around the stage of neuroendocrine cancer.
    • You may want to learn more about treatment options, including clinical trials and advanced technologies only available at an advanced center like Markey.
    • Your health insurance requires a second opinion before continuing toward treatment.

    Questions to ask when getting a second opinion

    After receiving a cancer diagnosis, you may have a lot on your mind. Here a few questions to keep in mind for your doctor when seeking a second opinion:

    • Is there a chance that my medical problem could have a different diagnosis?
    • Are there additional tests I should take before moving forward with treatment?
    • Do you recommend any treatments at this time?
    • What do you expect to happen if I wait or don't have the treatment?
    • What are the side effects of treatment?
    • How long are treatment recovery periods?