Chronic Lymphocytic Leukemia (CLL) targeted therapy

Targeted drugs, often paired with chemotherapy, are designed to take advantage of the specific vulnerabilities of your cancer cells. Your cancer cells are tested to determine which targeted drugs may be helpful.

The most common targeted therapy drugs used are:

  • Rituximab (Rituxan)®
  • Alemtuzumab (Campath)®
  • Ofatumumab (Arzerra)®
  • Obinutuzumab (Gazyva)®
  • Ibrutinib (Imbruvica)®
  • Idelalisib (Zydelig)®
  • Venetoclax (Venclexta)®

Rituximab, ofatumumab and obinutuzumab are given intravenously. Alemtuzumab is given either intravenously or by an injection just under the skin. Ibrutinib is given as a capsule by mouth. Idelalisib and venetoclax are given as a tablet by mouth.

Learn more

For more information on diagnosis, treatment and more of chronic lymphocytic leukemia, visit our CLL information pages below.

NCI Comprehensive Cancer Center - A Cancer Center Designated by the National Cancer Institute

Markey Cancer Center is designated by the National Cancer Institute as a Comprehensive Cancer Center – a distinction that recognizes our commitment to accelerating precision cancer research and care to patients. We are the first and only NCI-Comprehensive Cancer Center in Kentucky, and one of 57 in the nation.