Biospecimen Procurement and Translational Pathology Shared Resource Facility (BPTP SRF)

Director: Therese Bocklage, MD

Scientific Associate Director: Derek Allison, MD

Mission Statement

The Markey BPTP SRF collects, processes, annotates, stores and distributes biospecimens to support translational research in cancer and other diseases. Markey BPTP SRF support includes assistance in obtaining IRB certification, specimen queries, as well as the acquisition, processing, and send-out of targeted biospecimens in accordance with specific research protocols. We also maintain a full-service histology and IHC laboratory dedicated to research, which includes tissue microarray services and access to UK surgical archive materials, as well as molecular assays (in situ, TUNEL), Nanostring GeoMx Digital Spatial Analysis, and Halo/Halo AI image analysis. Our services are available to University of Kentucky (UK) faculty and other qualified investigators in partnership with UK faculty.

Combs Research Building, Room 113A 
800 Rose St., Lexington, KY 40536-0293 
Telephone: 859-257-4717
markey.bstp@uky.edu  

Prioritization of Services

The prioritization of services is based on the following criteria:

  1. MCC members with cancer-related, peer reviewed studies.
  2. MCC investigators preparing cancer-related, peer reviewed grant applications.
  3. MCC pilot/feasibility projects.
  4. MCC investigators not currently funded by peer reviewed grants.
  5. Non-cancer-related studies.

Request BPTP SRF Services

The BPTP SRF now uses the online program iLab to manage all service requests and billing, including:

  • Prospective Specimen Collections
  • Frozen or fixed specimen requests
  • Tissue Microarray requests
  • Histology and IHC
  • Self-serve Histology Equipment Reservations (microtome and cryostat)
  • Halo Workstation Reservation
  • Nanostring GeoMx Digital Spatial Analysis (Consult required) 
  • Specimen queries, feasibility queries, letters of support, budgets

To request any BPTP SRF services, visit the iLab landing page with more detailed instructions, including a one-time account setup. 

For questions or help in setting up your iLab account, or to schedule a consultation, please contact BPTP by email.

Biospecimen Inventory

To request samples, investigators are required to submit a request via iLab.

Visit this page for a complete and current inventory.

Acknowledgement

Investigators are required to acknowledge the Markey Cancer Center Biospecimen Procurement and Translational Pathology Shared Resource Facility (BPTP SRF) in any publications that result from the use of biospecimens or information received through the MCC BPTP SRF. For your convenience, you are welcome to use the following statement: 

“This research was supported by the Biospecimen Procurement and Translational Pathology Shared Resource Facility of the University of Kentucky Markey Cancer Center (P30CA177558).”

Cost Structure

The most up-to-date rates can be found on our iLab page. Please contact BPTP by email for a quote or estimate.

Frequently Asked Questions

What information comes with the specimens?

The type of information depends on what is requested by the investigator. In collaboration with Markey Cancer Research Informatics SRF, the Biospecimen Procurement and Translational Pathology Shared Resource Facility (BPTP SRF) can provide disease type (or control), age, gender, staging, histological diagnosis, smoking history, region, etc., with most specimens. Personal identifying information is not available to investigators

Is clinical history or follow-up information available?

Clinical history and follow-up data for cancer patients is generally available, with IRB approval, through a partnership with Markey Cancer Research Informatics and the Kentucky Cancer Registry/SEER database. Please contact the BPTP for more information. 

How do I get IRB approval?

Learn more about the Office of Research Integrity or request a non-human subjects determination from the IRB here.

What is ORIEN Avatar and how can I access data?

BPTP, in collaboration with Markey’s Precision Medicine Group, submits tumor and germline sequencing from eligible patients consented to the Markey Total Cancer Care Protocol for research grade whole exome sequencing and RNASeq. Learn more about the ORIEN protocol or submit a data request

Contact BPTP SRF Staff

Mailing Address

The Biospecimen Procurement and Translational Pathology Shared Resource Facility (BPTP SRF)
Combs Research Building, Room 113A
800 Rose St., Lexington KY 40536-0293
859-257-4717
markey.bstp@uky.edu

Personnel and Contact Information

Therese Bocklage, MD
BPTP SRF Director
William R. Willard Medical Education Building, MS 117
Lexington KY 40536-0298
859-323-7349
therese.bocklage@uky.edu

Derek Allison, MD
BPTP SRF Scientific Associate Director
William R. Willard Medical Education Building
Lexington KY 40536-0093
derek.allison@uky.edu

Dana Napier
BPTP Program Administrator
Combs Research Building, 108B
Lexington, KY 40536-0093
dana.napier@uky.edu

Markey Cancer Center is NCI-designated

The UK Markey Cancer Center was first designated by the National Cancer Institute in 2013 – a distinction that recognizes our extraordinary ability to provide world-class care for our patients. We are the only NCI-designated cancer center in Kentucky and one of only 71 in the nation.

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