Markey Cancer Center Research Programs

Research conducted at Markey focuses on Kentucky’s most serious cancer burdens. Our researchers emphasize finding solutions that will directly impact the “distressed” Appalachian Kentucky region, where cancer incidence and mortality rates surpass those for the entire state.

The MCC brings unique basic, clinical and population research strengths to this mission. Together, the researchers in each of our three research programs deliver transformative interventional research to an important underserved priority population. Their contributions to national efforts to conquer cancer through discovery, clinical translation, cancer prevention and community outreach provide Markey with a rich and dynamic research environment.

Cancer Prevention and Control (CP) Program

The Cancer Prevention and Control (CP) Program faculty and their studies focus on factors affecting Kentucky’s unusually high cancer incidence, morbidity and mortality. Their findings can be used to construct more effective cancer control interventions tailored toward the specific needs and issues faced by this important population.


Molecular and Cellular Oncology (MCO) Program

The Molecular and Cellular Oncology (MCO) Program faculty and their studies aim to gain a comprehensive understanding of basic mechanisms driving cancer initiation, progression, metastasis and therapeutic resistance to facilitate the development of novel and rational approaches for cancer prevention and therapy. 


Translational Oncology (TO) Program

The Translational Oncology (TO) Program faculty and studies focus on scientifically identifying novel targets, discovery of new anticancer agents and devices, and leading catchment-relevant clinical trials that decrease the cancer burden in Kentucky and the nation.


NCI Comprehensive Cancer Center - A Cancer Center Designated by the National Cancer Institute

Markey Cancer Center is designated by the National Cancer Institute as a Comprehensive Cancer Center – a distinction that recognizes our commitment to accelerating precision cancer research and care to patients. We are the first and only NCI-Comprehensive Cancer Center in Kentucky, and one of 57 in the nation.