Research conducted at Markey focuses on Kentucky’s most serious cancer burdens. Our researchers emphasize finding solutions that will directly impact the “distressed” Appalachian Kentucky region, where cancer incidence and mortality rates surpass those for the entire state.
The MCC brings unique basic, clinical and population research strengths to this mission. Together, the researchers in each of our four research programs deliver transformative interventional research to an important underserved priority population. Their contributions to national efforts to conquer cancer through discovery, clinical translation, cancer prevention and community outreach provide Markey with a rich and dynamic research environment.
The Cancer Prevention and Control (CP) Program faculty and their studies focus on factors affecting Kentucky’s unusually high cancer incidence, morbidity and mortality. Their findings can be used to construct more effective cancer control interventions tailored toward the specific needs and issues faced by this important population.
Learn more by visiting the Cancer Prevention and Control webpage.
The Cancer Cell Biology and Signaling (CS) Program focuses on investigating the basic signaling pathways and mechanisms by which cancer cells survive and proliferate through the body. Researchers in the CS program investigate the role of the microenvironment in nurturing tumor progression and in leading to metastasis.
Learn more by visiting the Cancer Cell Biology and Signaling webpage.
The Drug Discovery, Delivery, and Translational Therapeutics (DT) Program members use their scientific expertise to identify novel, specific targets and biomarkers, discover and develop new anticancer agents, and develop and participate in early phase clinical trials.
Learn more by visiting the Drug Discovery, Delivery, and Translational Therapeutics webpage.
The Genomic Instability, Epigenetics and Metabolism (GEM) Program strives to generate a comprehensive understanding of genomic instability, epigenetics, metabolism and DNA repair mechanisms to develop novel approaches for cancer prevention and therapy.
Learn more by visiting the Genomic Instability, Epigenetics and Metabolism webpage.