Molecular Tumor Board

The Markey Cancer Center Molecular Tumor Board (MTB) is a statewide service available to physicians at UK HealthCare and regional affiliates.

The MTB provides a forum for expert clinicians, pathologists and scientists to discuss and analyze tumor genotypes and molecular abnormalities in order to recommend patient-specific targeted therapies. 

The MTB is intended to supplement oncology tumor boards and includes a broad range of expert panel members.

Clinicians can order a genomic report and submit a case study to be presented for review by the MTB during their twice-monthly meetings. For an overview of the MTB, download the referral flyer below.

Leadership Contact Information

  • Jill Kolesar, PharmD, MS, Co-Directorrmillerjkolesar
  • Rachel Miller, MD, Co-Director

Molecular Tumor Board Office Phone: 1-844-622-0341

Click here to contact the tumor board by email, or email Dr. Kolesar directly.


Administrative Office

Abigail Anderson, PhD, aman239@uky.edu
MTB Project Manager

Rebecca Carpenter, rebecca.carpenter@uky.edu
Administrative Support Associate

Meetings

The Molecular Tumor Board (MTB) meets:

  • 12 p.m.
  • Every first and third Tuesday

MTB meetings are currently held via Zoom. Please email either Abigail Anderson, PhD or Rebecca Carpenter for Zoom details to attend.

Some MTB meetings will include a 15-minute informational update on Precision Medicine. 

To schedule a case presentation, review the details in the Case Submission section. All cases must be submitted to MTB seven days prior to the meeting date.

2022 MTB Meeting Schedule

Month Day / Tues Location
January 4 Zoom
January 18 Zoom
February 1 Zoom
February 15 Zoom
March 1 Zoom
March 15 Zoom
April 5 Zoom
April 19 Zoom
May 3 Zoom
May 17 Zoom
June 7 Zoom
June 21 Zoom
July 5 Canceled
July 19 Zoom
August 2 Zoom
August 16 Zoom
September 6 Zoom
September 20 Zoom
October 4 Zoom
October 18 Zoom
November 1 Zoom
November 15 Zoom
December 6 Zoom
December 20 Zoom

Continuing Medical Education (CME)

If clinicians or pharmacists want to obtain CE Credit for this meeting, they must attend the meeting in person or via teleconference, then enter the provided access code on the CE Central website. Any questions or concerns regarding CE Credit can be directed to the MTB Manager at mtb@uky.edu

Policy on Disclosure

It is the policy of the Markey Cancer Center that the faculty, authors, planners and other persons who may influence the content of this CME activity disclose all relevant financial relationships with commercial interests in order to allow CME staff to identify and resolve any potential conflicts of interest. Faculty must also disclose any planned discussions of unlabeled/unapproved uses of drugs or devices during their presentation.

Case Submission

Cases must be submitted at least seven days prior to the meeting date.

Genomics reports from UK HealthCare or external sources (Foundation, MATCH, etc.) can be submitted.

A patient's genomic report is required for case submission. Please see how to order a genomic report through UK HealthCare under Order a Genomic Report below. 

If you already have a genomic report, fill out the case submission form online, or download the form below.

The patient’s genomic report can be sent to MTB by email.

When the case submission and genomic report are received, the MTB manager will schedule the case for presentation and invite the treating clinician to the meeting.

Treatment recommendations will be discussed at the MTB meeting. Recommendation letters will be faxed and/or mailed or uploaded into the electronic health record per the preference of the submitting physician. Specify method of results reporting on the case submission form.

Note: There is no cost to submit a case to the Markey Cancer Center Molecular Tumor Board.

Order a Genomic Report

Genomic reports can be ordered through the Clinical Molecular and Genomic Pathology department. There is a comprehensive solid tumor panel, some gene-specific hematological panels as well as a larger hematological malignancy panel. Please see the information forms below on the methodology of the panels and what genes are included in the panels. 

To order a genomic report, the clinical staff must:

  1. Fill out the Requisition Form.
  2. Send tissue blocks to the address listed on the form: 800 Rose St. HA619, Lexington, KY 40536-0293

If you have any questions about ordering a genomic panel for your patient, please contact the Clinical Molecular and Genomic Pathology department at (859) 323-5327 or cmgp@uky.edu.

Solid tumor panels:

Hematologic Malignancy Panels:

Research

The Molecular Tumor Board currently has two prospective clinical trials evaluating integration of Precision Medicine into cancer therapeutics.

  • Part 1:  A prospective observational cohort study evaluating outcomes of genomic testing in patients with poor prognosis cancer.
  • Part 2: A therapeutic phase 2 sub-study evaluating genomic testing in human cancer and outcomes of targeted therapies recommended by an institutional multidisciplinary molecular tumor board in patients with poor prognosis cancer.

Researchers who are interested in using the data or specimen collected under these protocols must complete the data request form.

Guidance Documents

Guidance documents are used to establish guidelines for Molecular Tumor Board (MTB) recommendations for advanced cancer.

MTB guidance documents will be made available to download below.

Download Guidance MTB Documents

Contact Us

Directors

Site Leaders 

Jill Kolesar, PharmD
Professor, College of Pharmacy
Department of Pharmacy Practice and Science

Chandler Park, MD, FACP
Research Medical Director at Hardin Memorial Hospital, Central Kentucky Region
UK Markey Cancer Center Research Network

Rachel Ware Miller, MD
Associate Professor, Division of Gynecologic Oncology
Department of Obstetrics and Gynecology

 

Administrative Office

 

Abigail Anderson, PhD
MTB Project Manager
aman239@uky.edu

Rebecca Carpenter
Administrative Support Associate
rebecca.carpenter@uky.edu

 

Markey Cancer Center is NCI-designated

The UK Markey Cancer Center was first designated by the National Cancer Institute in 2013 – a distinction that recognizes our extraordinary ability to provide world-class care for our patients. We are the only NCI-designated cancer center in Kentucky and one of only 71 in the nation.

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