Biostatistics & Bioinformatics Shared Resource (BB SR)

The BB SR uses REDCap to manage project requests. To start using BB SR services, click the link below, which will take you to the REDCap form that you can fill out for project requests.

BB SR REDCap Project Request Form

Faculty

Staff

Not Pictured

• Bioinformatics Analyst: Ryan Goettl, MS
• Bioinformatics Analyst: Abu Saleh Mosa Faisal, MS
• Bioinformatics Analyst: Jinge Liu, PhD, MS
• Statistician: Ning Li, MS
• Graduate Research Assistant: Kris Varothai
• Graduate Research Assistant: Lu Zhang

For more information, contact markey.biostat@uky.edu.

Location
2365 Harrodsburg Road, Suite A230
Lexington, KY 40504-3381

To ensure that the BB SR supports high-quality research, the top three priority areas are: 1) investigators with peer-reviewed funded studies; 2) investigators with non-peer-reviewed funded studies and applying for peer-reviewed grants with proposed BB SR funding; and 3) investigators conducting MCC pilot studies and IITs.

Consultation and support for grant applications and clinical trial development are provided free of charge. BB SR also provides limited preliminary data analysis to formulate new hypotheses for proposals to be submitted for funding. More extensive support should provide funding of BB SR effort on individual grants. 

July 2023–February 2025

1. Hudson L, Burus T, Park L, Huang B (CP), Hull PC (CP), Vanderford NL. Cancer disparities in Appalachian Kentucky. J Rural Health 40:87-95, 2024. PMCID: PMC10593907 
    
2. Kunos CA, Fabian D, Fredericks T, Baldwin L (TO), Dietrich C (TO), Miller RW (TO), Ueland FR (TO). Hemoglobin level associates with survival in women from Appalachian Kentucky with uterine cervix cancer. Front Oncol 13:1132135, 2023. PMCID: PMC10358846 
    
3. Zhang Z, Wang X, Kim M, He D, Wang C (MCO), Fong KW (MCO), Liu X (MCO). Downregulation of EZH2 inhibits epithelial-mesenchymal transition in enzalutamide-resistant prostate cancer. Prostate. 2023 Nov;83(15):1458-1469. doi: 10.1002/pros.24602. Epub 2023 Jul 20. PMID: 37475584; PMCID: PMC11618820. 
    
4. Hao Z (TO), Chen Q, Huang B (CP). In Reply: Overall Survival of Resectable Metastatic Colon Cancer Treated With Neoadjuvant Chemotherapy or Adjuvant Chemotherapy in Non-academic Program. Oncologist 28:e590, 2023. PMCID: PMC10322135 
    
5. Paskett ED-INT, Kruse-Diehr AJ (CP), Oliveri JM-INT, Vanderpool RC, Gray DM-INT, Pennell ML-INT, Huang B (CP), Young GS, Fickle D-INT, Cromo M, Katz ML-INT, Reiter PL-INT, Rogers M, Gross DA-INT, Fairchild V-INT, Xu W-INT, Carman A, Walunis JM-INT, McAlearney AS-INT, Huerta TR-INT, Rahurkar S, Biederman E-INT, Dignan M (CP). Accelerating Colorectal Cancer Screening and Follow-up through Implementation Science (ACCSIS) in Appalachia: protocol for a group randomized, delayed intervention trial. Transl Behav Med 13:748-756, 2023. PMCID: PMC10538475 
    
6. Wang D-INT, Gao L-INT, Gao X-INT, Wang C (MCO), Tian S-INT. Identification of monotonically expressed long non-coding RNA signatures for breast cancer using variational autoencoders. PLoS One 18:e0289971, 2023. PMCID: PMC10414641 
    
7. Chen Q, Huang B (CP), Anderson AM, Durbin EB (CP), Arnold SM (TO), Kolesar JM. Association of first primary cancer with risk of subsequent primary cancer among survivors of adult-onset cancers in Kentucky and Appalachian Kentucky. Front Oncol 13:1193487, 2023. PMCID: PMC10470616 
    
8. Zhang JZ-INT, Wang C (MCO). A comparative study of clustering methods on gene expression data for lung cancer prognosis. BMC Res Notes 16:319, 2023. PMCID: PMC10630994 
    
9. Izumi T (MCO), Rychahou P, Chen L (TO), Smith MH, Valentino J (TO). Copy Number Variation That Influences the Ionizing Radiation Sensitivity of Oral Squamous Cell Carcinoma. Cells 12:2425, 2023. PMCID: PMC10605269 
    
10. Washington B, Cheek D (TO), Fabian D, Kudrimoti M, Pokhrel D (TO), Wang C (MCO), Thayer-Freeman C, Luo W. Effects of Interfraction Dose Variations of Target and Organs at Risk on Clinical Outcomes in High Dose Rate Brachytherapy for Cervical Cancer. Cancers (Basel) 15:4862, 2023. PMCID: PMC10571581 
     
11. Hasani S, Young LEA, Van Nort W, Banerjee M, Rivas DR, Kim J, Xiong X, Sun RC-INT, Gentry MS-INT, Sesaki H-INT, Gao T (MCO). Inhibition of mitochondrial fission activates glycogen synthesis to support cell survival in colon cancer. Cell Death Dis 14:664, 2023. PMCID: PMC10564897 
     
12. Zhang J, Liu Y, Wang C (MCO), Vander Kooi CW, Jia J (MCO). Phosphatidic acid binding to Patched contributes to the inhibition of Smoothened and Hedgehog signaling in Drosophila wing development. Sci Signal 16:eadd6834, 2023. PMCID: PMC10661859 
     
13. Li C, Allison DB (TO), He D, Mao F, Wang X, Rychahou P, Imam IA, Kong Y, Zhang Q, Zhang Y, Liu J (MCO), Wang R, Rao X, Wu S, Evers BM (TO), Shao Q, Wang C (MCO), Li Z (MCO), Liu X (MCO). Phosphorylation of AHR by PLK1 promotes metastasis of LUAD via DIO2-TH signaling. PLoS Genet 19:e1011017, 2023. PMCID: PMC10662729
     
14. McDonald HG, Zaki OA, Wright MJ, Jayswal R, Weiss H (TO), Nair RT, Ganesh H, Ellis S, Kolesar JM (TO), Moss J, Barry-Hundeyin M (TO), Pandalai PK (TO), Kim J (TO), Patel RA (TO), Cavnar MJ (TO). Phase I Safety and Feasibility Pilot of Hepatic Artery Infusion Chemotherapy in a Rural Catchment Area Using The Codman Vascular Catheter with The Medtronic SynchroMed II Pump for Intrahepatic Cancers. Ann Surg Oncol. 2024 Feb;31(2):1252-1263. doi: 10.1245/s10434-023-14519-8. Epub 2023 Nov 25. PMID: 38006531; PMCID: PMC11466354. 
     
15. Christian WJ (CP), Walker CJ, McDowell J, Huang B (CP), Tucker TC (CP), Villano J (TO), Durbin EB (CP). Geographic and temporal trends in pediatric and young adult brain tumors in Kentucky, 1995-2019. Cancer Epidemiol 88:102499, 2024. PMCID: PMC10842684
     
16. Collette K, Perkey CL, Adams V, Shelton BJ (CP), Corum LS, Butts A. Impact of relative dose intensity on pathologic complete response in human epidermal growth factor receptor 2 positive breast cancer patients receiving neoadjuvant TCHP. J Oncol Pharm Pract. 2024 Dec;30(8):1335-1342. doi: 10.1177/10781552231212206. Epub 2023 Nov 7. PMID: 37936380; PMCID: PMC11972010. 
     
17. Zhang X, Su Y-INT, Lane AN (TO), Stromberg AJ, Fan TWM (MCO), Wang C (MCO). Correction: Bayesian kinetic modeling for tracer-based metabolomic data. BMC Bioinformatics 25:14, 2024. PMCID: PMC10782720 
     
18. DuCote TJ, Song X, Naughton KJ, Chen F, Plaugher DR, Childress AR, Gellert AR, Skaggs EM, Qu X-INT, Liu J-INT, Liu J (MCO), Li F-INT, Wong KK-INT, Brainson CF (MCO). EZH2 Inhibition Promotes Tumor Immunogenicity in Lung Squamous Cell Carcinomas. Cancer Res Commun 4:388-403, 2024. PMCID: PMC10863487 
     
19. McLouth LE (CP), Stapleton JL (CP), Bursac V, Zelaya CM-INT, Shelton BJ (CP), Thakur K, Hands I, Blu C, Chih MY (CP), McFarlin JM. Piloting a Patient Tool to Aid Palliative Care Referrals during Advanced Lung Cancer Treatment. J Pain Symptom Manage 67:337-345.e2, 2024. PMCID: PMC10939763 
     
20. Siegel DA-INT, Durbin EB (CP), Pollock BH-INT, Grimes A-INT, Ji L-INT, Alonzo TA-INT, Vargas SL, Huang B (CP), McDowell JR, Lycan E, Ransdell P, Tai E-INT, Roth ME-INT, Freyer DR-INT. Population-Based Data Linkage Describing Patterns of Cancer Clinical Trial Enrollment Among Children and Adolescents. JCO Oncol Pract 20:631-642, 2024. PMCID: PMC11090697 
     
21. Trott S, Lei F, Jay Christian W (CP), Mao X, Lehmkuhl B, Kejner A-INT. Geographic variation of HPV-associated cancer incidence in Kentucky using spatial scan statistics. Cancer Causes Control 35:817-824, 2024. PMCID: PMC11346267 
     
22. Burus T, Lei F, Huang B (CP), Christian WJ (CP), Hull PC (CP), Ellis AR, Slavova S, Tucker TC (CP), Lang Kuhs KA (CP). Undiagnosed Cancer Cases in the US During the First 10 Months of the COVID-19 Pandemic. JAMA Oncol 10:500-507, 2024. PMC10884945 
     
23. McLouth LE (CP), Shelton BJ (CP), Bursac V, Burris JL (CP), Cheavens JS-INT, Weyman K-INT, Peterman AH-INT, Corum L, Studts JL-INT, Arnold SM (TO). "Pathways": A hope-enhancing intervention for patients undergoing treatment for advanced lung cancer. Psychooncology 33:e6316, 2024. PMCID: PMC11157457 
     
24. Stapleton JL (CP), Manne SL-INT, Pagoto SL-INT, Leip A, Greene K-INT, Hillhouse JJ-INT, Merritt AS, Shelton BJ (CP). A Social Media-Delivered Melanoma Prevention Program for Young Women Engaged in Frequent UV Tanning: Protocol for a Randomized Controlled Trial. JMIR Res Protoc 13:e56562, 2024. PMCID: PMC10988380
     
25. Karanth S-INT, Osazuwa-Peters OL-INT, Wilson LE-INT, Previs RA-INT, Rahman F-INT, Huang B (CP), Pisu M-INT, Liang M-INT, Ward KC-INT, Schymura MJ, Berchuck A-INT, Akinyemiju TF-INT. Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer. Cancer Res Commun 4:811-821, 2024. PMCID: PMC10946308 
     
26. Li J, Yang L, Song J, Yan B, Morris AJ-INT, Moseley H (MCO), Flight R, Wang C (MCO), Liu J (MCO), Weiss HL (TO), Morris EF-INT, Abdelhamid I, Gerl MJ, Melander O-INT, Smyth S-INT, Evers BM (TO). Neurotensin accelerates atherosclerosis and increases circulating levels of short-chain and saturated triglycerides. Atherosclerosis 392:117479, 2024. PMCID: PMC11088984 
     
27. Osazuwa-Peters OL-INT, Deveaux A-INT, Muehlbauer MJ-INT, Ilkayeva O-INT, Bain JR-INT, Keku T-INT, Berchuck A-INT, Huang B (CP), Ward K-INT, Gates Kuliszewski M, Akinyemiju T-INT. Racial Differences in Vaginal Fluid Metabolites and Association with Systemic Inflammation Markers among Ovarian Cancer Patients: A Pilot Study. Cancers (Basel) 16:1259, 2024. PMCID: PMC11011195 
     
28. Zeng T, Zhang JZ-INT, Stromberg A, Chen J-INT, Wang C (MCO). Strategies for improving the performance of prediction models for response to immune checkpoint blockade therapy in cancer. BMC Res Notes 17:102, 2024. PMCID: PMC11005243 
     
29. Burus T, Damgacioglu H-INT, Huang B (CP), Christian WJ (CP), b, Ellis AR, Arnold SM (TO), Deshmukh AA-INT, Lang Kuhs KA (CP). Trends in Oral Tongue Cancer Incidence in the US. JAMA Otolaryngol Head Neck Surg 150:436-443, 2024. PMCID: PMC11082689 
     
30. Burus T, Thompson JR, McAfee CR, Williams LB (CP), Knight JR (CP), Huang B (CP), Kanotra S, Wilhite NP, Russell E, Rogers M, Sorrell CL, Stroebel C, King R, Hull PC (CP). A framework and process for community-engaged, mixed-methods cancer needs assessments. Cancer Causes Control. 2024 Oct;35(10):1319-1332. doi: 10.1007/s10552-024-01892-2. Epub 2024 May 29. PMID: 38809305; PMCID: PMC11461567. 
     
31. Chow Z, Johnson J, Chauhan A, Jeong JC (TO), Castle JT, Izumi T (MCO), Weiss H (TO), Townsend CM Jr, Schrader J, Anthony L (TO), Yang ES (TO), Evers BM (TO), Rychahou P. Inhibition of ribonucleotide reductase subunit M2 enhances the radiosensitivity of metastatic pancreatic neuroendocrine tumor. Cancer Lett. 2024 Aug 1;596:216993. doi: 10.1016/j.canlet.2024.216993. Epub 2024 May 25. PMID: 38801884; PMCID: PMC11299177. 
     
32. Drury J, Geisen ME, Tessmann JW, Rychahou PG, Kelson CO, He D, Wang C (MCO), Evers BM (TO), Zaytseva YY (MCO). Overexpression of Fatty Acid Synthase Upregulates Glutamine-Fructose-6-Phosphate Transaminase 1 and O-Linked N-Acetylglucosamine Transferase to Increase O-GlcNAc Protein Glycosylation and Promote Colorectal Cancer Growth. Int J Mol Sci 25:4883, 2024. PMCID: PMC11084459 
     
33. Tessmann JW, Deng P, Durham J, Li C, Banerjee M, Wang Q (MCO), Goettl RA, He D, Wang C (MCO), Lee EY, Evers BM (TO), Hennig B, Zaytseva YY (MCO). Perfluorooctanesulfonic acid exposure leads to downregulation of 3-hydroxy-3-methylglutaryl-CoA synthase 2 expression and upregulation of markers associated with intestinal carcinogenesis in mouse intestinal tissues. Chemosphere. 2024 Jul;359:142332. doi: 10.1016/j.chemosphere.2024.142332. Epub 2024 May 14. PMID: 38754493; PMCID: PMC11157449. 
     
34. Kong Y, Li C, Liu J (MCO), Wu S, Zhang M, Allison DB (TO), Hassan F, He D, Wang X, Mao F, Zhang Q, Zhang Y, Li Z (MCO), Wang C (MCO), Liu X (MCO). Single-cell analysis identifies PLK1 as a driver of immunosuppressive tumor microenvironment in LUAD. PLoS Genet 20:e1011309, 2024. PMCID: PMC11182521
     
35. Wang M, Xie Y, Liu J (MCO), Li A, Chen L (TO), Stromberg A, Arnold SM (TO), Liu C, Wang C (MCO). A Probabilistic Approach to Estimate the Temporal Order of Pathway Mutations Accounting for Intra-Tumor Heterogeneity. Cancers (Basel). 2024 Jul 8;16(13):2488. doi: 10.3390/cancers16132488. PMID: 39001551; PMCID: PMC11240401. 
     
36. Zhang Y, Fong KW (MCO), Mao F, Wang R, Allison DB (TO), Napier D, He D, Liu J (MCO), Zhang Y, Chen J, Kong Y, Li C, Li G, Liu J (MCO), Li Z (MCO), Zhu H, Wang C (MCO), Liu X (MCO). Elevating PLK1 overcomes BETi resistance in prostate cancer via triggering BRD4 phosphorylation-dependent degradation in mitosis. Cell Rep. 2024 Jul 23;43(7):114431. doi: 10.1016/j.celrep.2024.114431. Epub 2024 Jul 4. PMID: 38968071; PMCID: PMC11334074. 
     
37. Rives TA, Collard J, Li N, Yan D, Dietrich CS (TO), Miller RW (TO), Ueland FR (TO), Pickarski J, Kolesar JM (TO). Clinical Utility of Molecular Tumor Board Review for Identification of Possible Germline Pathogenic Variants on Tumor Next-Generation Sequencing Reports. JCO Precis Oncol. 2024 Sep;8:e2400301. doi: 10.1200/PO.24.00301. PMID: 39259913; PMCID: PMC11404756. 
     
38. Burus T, Lei F, Huang B (CP), Christian WJ (CP), Hull PC (CP), Ellis AR, Slavova S, Tucker TC (CP), Lang Kuhs KA (CP). COVID-19 and Rates of Cancer Diagnosis in the US. JAMA Netw Open. 2024 Sep 3;7(9):e2432288. doi: 10.1001/jamanetworkopen.2024.32288. PMID: 39240562; PMCID: PMC11380103. 
     
39. Li C, Zhou Y, Jiang Y, Yin Z, Weiss HL (TO), Wang Q (MCO), Evers BM (TO). miR-27a-3p regulates intestinal cell proliferation and differentiation through Wnt/β-catenin signalling. Cell Prolif. 2025 Feb;58(2):e13757. doi: 10.1111/cpr.13757. Epub 2024 Sep 27. PMID: 39329245; PMCID: PMC11839187. 
     
40. Di J, Alhaidary AM, Wang C (MCO), Liu J, Wei S, Valentino J (TO), Bocklage TJ (MCO). NSD3::NUTM1 Fusion Sarcoma Mimicking Malignant Peripheral Nerve Sheath Tumor with Prolonged Survival. Biomedicines. 2024 Aug 1;12(8):1709. doi: 10.3390/biomedicines12081709. PMID: 39200173; PMCID: PMC11351216. 
     
41. Kunos CA, Miller RW (TO), Fabian D. Cisplatin-Containing Combinations Associate with Survival in Women from Appalachian Kentucky with Metastatic, Persistent, or Recurrent Uterine Cervix Cancer. Cancers (Basel). 2024 Sep 28;16(19):3319. doi: 10.3390/cancers16193319. PMID: 39409939; PMCID: PMC11475045. 
     
42. Kelson CO, Tessmann JW, Geisen ME, He D, Wang C (MCO), Gao T (MCO), Evers BM (TO), Zaytseva YY (MCO). Upregulation of Fatty Acid Synthase Increases Activity of β-Catenin and Expression of NOTUM to Enhance Stem-like Properties of Colorectal Cancer Cells. Cells. 2024 Oct 8;13(19):1663. doi: 10.3390/cells13191663. PMID: 39404424; PMCID: PMC11475157. 
     
43. Subramanian S, Kobrin S, Hoover S, Tan S, Brenner AT, Campbell JE, Hatcher J, Huang B (CP), Jones M, Kenzie ES, Lam H, Liebovitz D, Mishra SI, O'Leary MC, Ortwine KN, Pankratz VS, Paskett ED, Pennell M, Petrik AF, Roesch S. Harmonizing data across the accelerating colorectal cancer screening and follow-up through implementation science (ACCSIS) program to enhance data quality and promote data sharing. BMC Health Serv Res. 2024 Nov 6;24(1):1356. doi: 10.1186/s12913-024-11542-7. PMID: 39506739; PMCID: PMC11539253. 
     
44. Chen M, Karimpour PA, Elliott A, He D, Knifley T, Liu J (MCO), Wang C (MCO), O'Connor KL (MCO). Integrin α6β4 Upregulates PTPRZ1 Through UCHL1-Mediated Hif-1α Nuclear Accumulation to Promote Triple-Negative Breast Cancer Cell Invasive Properties. Cancers (Basel). 2024 Oct 31;16(21):3683. doi: 10.3390/cancers16213683. PMID: 39518121; PMCID: PMC11545476. 
     
45. Huckvale ED, Moseley HNB (MCO). Predicting the Pathway Involvement of All Pathway and Associated Compound Entries Defined in the Kyoto Encyclopedia of Genes and Genomes. Metabolites. 2024 Oct 27;14(11):582. doi: 10.3390/metabo14110582. PMID: 39590818; PMCID: PMC11596622. 
     
46. Di J, Yenwongfai LN, Arshad T, Huang B (CP), McDowell JK, Durbin EB (CP), Munker R (TO), Wei S. Prognostic Significance and Treatment Response Associations of Genetic Mutations in Chronic Myelomonocytic Leukemia: A Retrospective Cohort Study. Biomedicines. 2024 Oct 28;12(11):2476. doi: 10.3390/biomedicines12112476. PMID: 39595041; PMCID: PMC11591710. 
     
47. Ho J, Sukati S, Taylor T, Carter S, Fuller B, Marmo A, Sorge C, D'Orazio J (MCO), Butterfield DA (MCO), Bondada S, Weiss H (TO), St Clair DK, Chaiswing L (MCO). Extracellular vesicles released by ALL patients contain HNE-adducted proteins: Implications of collateral damage. Free Radic Biol Med. 2025 Feb 1;227:312-321. doi: 10.1016/j.freeradbiomed.2024.12.006. Epub 2024 Dec 4. PMID: 39643137; PMCID: PMC11786608. 
     
48. Cassim E, McDonald H, Harper M, Chen Q, Lin M, Patel R (TO), Cavnar M (TO), Pandalai P, Huang B (CP), Hull PC (CP), Kim J (TO), Burke E (TO). Treatment at an Academic Medical Center Eliminates Survival Disparities for Appalachian Kentuckians with Pancreatic Ductal Adenocarcinoma. J Appalach Health. 2024 Sep 1;6(1-2):6-20. doi: 10.13023/jah.0601.02. PMID: 39640244; PMCID: PMC11617027. 
     
49. Mobley JM, Phillips KI, Chen Q, Reusch E, Reddy N, Magsam JB, McLouth LE (CP), Huang B (CP), Villano JL (TO). Outcomes of Brain Metastasis from Lung Cancer. Cancers (Basel). 2025 Jan 14;17(2):256. doi: 10.3390/cancers17020256. PMID: 39858037; PMCID: PMC11764313. 
     
50. Akbari F, Liu X, Hamedi F, Mohtasebi M, Chen L (TO), Chen L, Yu G (TO). Programmable scanning diffuse speckle contrast imaging of cerebral blood flow. Neurophotonics. 2025 Jan;12(1):015006. doi: 10.1117/1.NPh.12.1.015006. Epub 2025 Jan 27. PMID: 39872020; PMCID: PMC11770344. 
     
51. Ganguly S, Burikhanov R, Sviripa VM, Ellingson S (TO), Jiang J, Gosser CM, Orren D, Goellner EM, Shenoy GG, Rao M, D'Orazio J (MCO), Brainson CF (MCO), Zhan CG (TO), Spielmann PH, Watt DS, Rangnekar VM (TO). S6K1 is a Targetable Vulnerability in Tumors Exhibiting Plasticity and Therapy Resistance. Int J Biol Sci. 2025 Jan 1;21(2):454-472. doi: 10.7150/ijbs.96672. PMID: 39781466; PMCID: PMC11705648. 
     
52. Cui X, Hou L, Yan B, Liu J (MCO), Zhang C, Sui P, Tong S (TO), Luchsinger L, Mendelson A, Zhou D, Yang FC, Zhong H, Liang Y. Sexual dimorphism in the mouse bone marrow niche regulates hematopoietic engraftment via sex-specific Kdm5c/Cxcl12 signaling. J Clin Invest. 2025 Jan 21;135(5):e182125. doi: 10.1172/JCI182125. PMID: 39836478; PMCID: PMC11870739. 
     
53. Kunos CA (TO), Piekarz R, Collins JM, Kinsella TJ. A case report of typhlitis during novel use of ropidoxuridine-capecitabine-radiotherapy for treatment-naïve rectal cancer. Cancer Chemother Pharmacol. 2023 Aug;92(2):151-155. doi: 10.1007/s00280-023-04561-4. Epub 2023 Jun 27. PMID: 37369852; PMCID: PMC10326127. 
     
54. Duff AJ, Otieno CO, Chen L (TO), Mannion K, Topf MC, Michels BE, Butt J, Woodward BO, Lima MC, Erdem H, Leonard MA, Turner MM, Waterboer T, Sudenga SL, Lang Kuhs KA (CP). Human Papillomavirus Type 16 E6 Seroprevalence among Men Living with HIV without HPV-Driven Malignancies. Cancer Prev Res (Phila). 2025 Apr 1;18(4):189-195. doi: 10.1158/1940-6207.CAPR-24-0420. PMID: 39907040; PMCID: PMC11961317. 
     
55.  Zhang C, Cui X, Liu Y, Wang F, Signer R, Nattamai K, Zhou D, Zheng Y, Geiger H, Wan F, Liang Y (MCO). Latexin deletion protects against radiation-induced hematopoietic damages via selective activation of Bcl-2 prosurvival pathway. Haematologica. 2023 Dec 1;108(12):3464-3470. doi: 10.3324/haematol.2022.282028. PMID: 37345464; PMCID: PMC10690908. 

Bioinformatics

• bacr is an R package developed by Dr. Chi Wang for implementing the Bayesian Adjustment for Confounding (BAC) method for estimating the average causal effect of a treatment on an outcome from cohort studies.
• NanoStringDiff is an R/Bioconductor package developed by Dr. Chi Wang to perform differential expression analysis based on gene expression data generated from the NanoString nCounter system. In addition, a user-friendly web application, NanoStringDiffWeb, is available here.
• “paf” R package: Calculate unadjusted/adjusted attributable fraction function of a set of covariates for a censored survival outcome from a Cox model using the method proposed by Chen, Lin and Zeng (Biometrika 97, 713-726, 2010).
• “KENDL” R Package: Calculate the kernel-smoothed nonparametric estimator for the exposure distribution in presence of detection limits using the method proposed by Yang et al. (Sat. Med 36(18), 2935-2946, 2017)