Nichole Danielle Allred, PhD
Dr. Nicole Danielle Allred is an Associate Professor of Biochemistry at Wake Forest School of Medicine.
Investigation of the Metabolomic Architecture of Obesity Implicates a “Mystery Metabolite” in Cardiometabolic Disease
Date: November 2, 2021, 12 - 1:30 p.m.
Nichole Allred, PhD, is a molecular biologist with a research focus of understanding the genetic architecture of complex diseases and underlying risk factors in minority populations. With an emphasis on metabolic disease, her research focuses on type 2 diabetes, nephropathy, obesity, liver disease and cardiovascular disease (CVD). She was awarded a K99/R00 Pathway to Independence award, which advanced her expertise in the areas of high-throughput genotyping technologies and quantitative intermediate phenotype analysis and interpretation. Her lab integrates a wide range of genetic, transcriptomic, metabolomic and bioinformatic approaches to understand disease pathophysiology. To provide broader context to the research findings, Allred is involved in multiple large-scale collaborative projects.
Jonathan R. Brestoff, MD, PhD, MPH
Dr. Jonathan R. Brestoff is Assistant Professor, Pathology & Immunology at Washington University School of Medicine in St. Louis.
Cell-to-cell transfer of mitochondria in obesity and aging
Date: November 4, 2021, 3 - 4:30 p.m.
Jonathan R. Brestoff, MD, PhD, MPH is a physician-scientist interested in understanding how the immune system and endocrine organs interact to regulate metabolic homeostasis and the pathogenesis of obesity and type 2 diabetes. He received his MD and PhD from the Perelman School of Medicine at the University of Pennsylvania, where he worked with Dr. David Artis to study how Interleukin (IL)-33 and Group 2 innate lymphoid cells (ILC2s) regulate beige fat function and the development of obesity. He then completed residency in Clinical Pathology at Washington University School of Medicine (WashU) and Barnes-Jewish Hospital, working with Dr. Steven Teitelbaum before starting his independent laboratory at WashU as a recipient of the NIH Director’s Early Independence Award (DP5) and Burroughs Wellcome Fund Career Award for Medical Scientists. The Brestoff Lab continues to study immunometabolism and how immune cells and adipocytes interact to regulate local and systemic metabolism.
Kristina Utzschneider, MD
Dr. Kristina Utzschneider is an Associate Professor in the Medicine Division of Metabolism, Endocrinology and Nutrition at University of Washington.
Digging deeper into the pathogenesis of hyperglycemia: additional insights from modeling
Date: November 11, 2021, 3 - 4:30 p.m.
Kristina Utzschneider, MD, is a board-certified physician at the VA Puget Sound, director of the VA Diabetes Care Program and a UW associate professor of Medicine and Metabolism, Endocrinology and Nutrition. She earned her medical degree . from Harvard and completed residency and fellowship at the University of Washington. She is a clinical researcher focused on the pathogenesis, treatment and prevention of type 2 diabetes. Her research has explored the effects of medications and diet on liver fat, insulin sensitivity and beta-cell function.
Kevan Herold, MD
Dr. Kevan Herold is C.N.H. Long Professor of Immunobiology and of Medicine (Endocrinology) at Yale School of Medicine.
Treatment and prevention of Type 1 diabetes, has the time come?
Date: November 18, 2021, 3 - 4:30 p.m.
Kevan Herold, MD, is a researcher in translational immunology. He is interested in understanding the basis for autoimmune diseases and developing new therapies based on our understanding of disease mechanisms. His focus has largely been in the field of autoimmune type 1 diabetes. His work encompasses basic laboratory work and clinical studies to understand the regulation of autoreactive T cells as well as clinical trials that involve novel therapeutics. As part of these studies, he is interested in analysis of beta cell function in type 1 diabetes, studying the development of autoimmune diabetes in patients with cancers who are treated with checkpoint inhibitors. His lab’s clinical and basic studies are focused on understanding how beta cells are destroyed and react to inflammation. With the COVID-19 pandemic, he and his colleagues have been studying the immunologic basis for responses in children and adults who are hospitalized with COVID-19 to understand the mechanisms that can lead to disease protection.
Researchers from the University of Kentucky and other regional institutes share their current findings and ongoing research about the alarming rise in obesity and diabetes rates. Abstracts are being collected for poster presentations. Instructions are below:
- Submit abstracts on the registration site by October 1st.
- Titles should include authors and affiliations. Submission of an abstract constitutes a commitment to and awareness by the author(s) for the studies described within the abstract.
- The body of the abstract must not exceed 2,000 characters including spaces.
- Use headings for Introduction, Methods, Results, and Conclusions.
- Do not include references in abstracts.
- Include actual data in the form of numbers rather than graphs.
- Grant Support: if any, please include funding source and identifying number at the end of the abstract.
- Submit one Power Point slide poster and five slides with audio presentation describing poster in detail between 5-8 minutes long. Additional information for uploading slides will be provided.
- Author(s) must display in the poster the studies described within the abstract.
- Posters will be judged on a session 11/5, and awardees will be featured in platform presentations on 12/9.
- UK Barnstable Brown Diabetes Center
- The Center of Research in Obesity and Cardiovascular Disease – (P30GM127211) from the National Institute of General Medical Sciences (NIGMS)
- University of Kentucky Department of Pharmacology & Nutritional Sciences