Pharmacokinetics and Anticoagulation Service

The Clinical Pharmacokinetics and Anticoagulation Service Guidelines were developed to ensure safe and efficacious dosage regimens through the application of pharmacokinetic/pharmacodynamic principles and the determination of drug serum concentrations.

Standard Guidelines

The policy/procedure manual outlines standard guidelines which should be followed when providing clinical pharmacokinetic monitoring of the following drugs:

  • Aminoglycosides
  • Carbamazepine
  • Digoxin
  • Direct Oral Anticoagulants
  • Direct Thrombin Inhibitors
  • Enoxaparin
  • Fosphenytoin
  • Lidocaine
  • Lithium
  • Phenobarbital
  • Phenytoin (free and total)
  • Procainamide
  • Quinidine
  • Theophylline
  • Valproic acid
  • Vancomycin
  • Warfarin

HIT and VTE Guidelines

In addition to the above list UK HealthCare pharmacy services has guidelines for Heparin Induced Thrombocytopenia (HIT) and the assessment and management of Venous Thromboembolism (VTE) prophylaxis.