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About

Patrick O'Donnell received his medical and doctorate degrees from Indiana University School of Medicine, Indianapolis. He completed a residency in orthopaedic surgery at the University of Minnesota, Minneapolis. He then completed a fellowship in musculoskeletal oncology at the University of Toronto, Mt. Sinai Hospital, Princess Margaret Cancer Center, Toronto, Ontario, Canada.

O'Donnell is currently a Professor and the director of the Sarcoma Program at the University of Kentucky Markey Cancer Center.

Personal Statement

As an orthopaedic oncologist, I get to treat both adult and pediatric patients. I operate on every bone in the body so I get many different surgeries, and it's made me a better surgeon. I treat many different types of cancers, including tumors that have started outside the bone and tumors that have spread inside the bone.

I help people by performing reconstructive surgery. We often help patients who have periprosthetic fractures with tumor-style prosthesis. Additionally, we are able to use many surgical techniques to help patients who don’t have cancer.

Patients who previously had no options for their hip or knee have options now. We can replace entire bones, including the femur, the biggest bone in the body. We can provide a cancer-style prosthesis that we connect with a knee replacement and a hip replacement and provide patients a new leg to walk on.

Faculty Rank

  • Professor of Orthopaedics
  • fixes empty view field issue
    Patrick O'Donnell, MD, PhD - UK HealthCare
  • Podcast

    When to have a hip or knee replacement

    Dr. Patrick O'Donnell explains when hip and knee reconstruction might be the right option for patients.

Training & Education

Degree

Indiana University, School of Medicine, Indianapolis

Residency

University of Minnesota Medical Center, Minneapolis

Fellowship

University of Toronto, Mt. Sinai Hospital, Toronto, Ontario, Canada

Certifications and Special Training

American Board of Orthopaedic Surgery

Insurance Information

Insurance policies can vary widely. Please check with your doctor/clinic for specific insurance information before your visit or procedure to avoid unexpected out-of-pocket costs.

See list of insurers

Patient Stories

Related News

Ratings & Reviews

4.75 out of 5
48 Reviews

The star rating is a calculation based on feedback from our patients using our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more about our survey process. Responses are measured on a scale of 1 to 5 with 5 being the best score.

  • Patient Review

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    September 2nd 2025
    Dr. O'Donnell was so considerate of my pain and treatment. He explain and answer every question I asked. He made feel at ease and confident about my situation.

    Patient Review

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    August 26th 2025
    A great Dr.

    Patient Review

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    August 26th 2025
    I do recommend them alot !

    Patient Review

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    August 12th 2025
    Dr. O'Donnell came highly recommended and explained clearly the future care needed.

    Patient Review

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    August 12th 2025
    I feel so blessed to have Dr. O'Donnell as my doctor, he is definitely the one who is going to do my knee replacement!!!
    • Patient Review

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      August 12th 2025
      Very efficient appointment. Everyone was excellent.
    • Patient Review

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      August 5th 2025
      Dr. O'Donnell was very patient with all of my husband's questions
    • Patient Review

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      July 29th 2025
      Good
    • Patient Review

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      July 29th 2025
      I felt well-informed and confident about the plan we had in preparation for surgery
    • Patient Review

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      July 28th 2025
      Dr O Donnell and all his staff were efficient and kind when speaking with us
    • Patient Review

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      July 22nd 2025
      I was very impressed with how much time Doctors Reynolds and O'Donnell spent with me. Dr O'Donnell showed great concern for my problems and was extremely knowledgeable of my situation.
    • Patient Review

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      July 22nd 2025
      I asked for more advice and context and they were immediately agreeable
    • Patient Review

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      July 15th 2025
      Could not have better. Way better than most.
    • Patient Review

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      July 8th 2025
      Dr O'Donnell is an experienced and caring physician. The best.
    • Patient Review

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      July 1st 2025
      Excellent experience with Allie and Dr O'Donnell
    • Patient Review

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      June 17th 2025
      Good
    • Patient Review

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      June 3rd 2025
      Overall great experience.
    • Patient Review

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      May 27th 2025
      Excellent continued care.
    • Patient Review

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      May 27th 2025
      Great
    • Patient Review

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      May 20th 2025
      Dr. O'Donnell was very concerned and encouraging. He is one in a million.
    • Patient Review

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      April 29th 2025
      Absolutely the best. I ditched the VA to get treatment with him.
    • Patient Review

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      March 18th 2025
      This Doctor I seen was Awesome!!
    • Patient Review

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      March 17th 2025
      I am more than pleased with Dr O'Donnell's concern for my issue and for his straightforward approach. He is friendly and instills confidence.
    • Patient Review

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      March 11th 2025
      As I stated before, your office provided no help. I did get shots. Actually the Nurse practitioner, after the intern kept running on about the knee replacement and I demanded to see the nurse practitioner I have always seen, seemed unconcerned and bit miffed that I demanded to see her, actually rolling her eyes after asking for a shot in my left knee.
    • Patient Review

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      March 11th 2025
      Una enfermera
    • Patient Review

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      March 4th 2025
      Love this practice
    • Patient Review

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      March 4th 2025
      Dr O'Donnell's the best
    • Patient Review

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      February 25th 2025
      Dr. O'Donnells assessment of my situation was comprehensive and clearly explained to me during my visit. He actively listened to my concerns and incorporated the information while considering the next steps for my care. This is the heart comprehensive health care and Dr. O'Donnell has it in spades. Don't ever let him go!
    • Patient Review

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      February 25th 2025
      Wonderful experience
    • Patient Review

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      February 25th 2025
      My total experience was very professional, informative, and caring. I wound highly recommend this doctor!
    • Patient Review

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      February 18th 2025
      Great team
    • Patient Review

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      February 17th 2025
      It was a very good experience
    • Patient Review

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      February 11th 2025
      I will visit again one day
    • Patient Review

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      February 11th 2025
      I wish he was more transparent in our discussions. We did not leave feeling we were equipped with the knowledge he could have provided. He repeated the same phrases over and over instead of expanding upon the questions we did ask.
    • Patient Review

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      February 10th 2025
      He did not explain why he came to a decision and back it up with facts. He simply said, it's an enchondroma. I know because I've seen several before. Very condescending when answering my questions, like how do I know that for sure and rule other things out? He seemed disinterested with my whole situation and uncaring ahead it my pain.
    • Patient Review

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      January 28th 2025
      This guy is the best !!!!!
    • Patient Review

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      January 28th 2025
      Dr. O'Donnell is great at listening to my concerns. And is a terrific surgeon. I would absolutely recommend him to others.
    • Patient Review

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      January 14th 2025
      The providers in this clinic always listen to my concerns and are very willing to individualize treatment based on need
    • Patient Review

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      January 14th 2025
      I tell everyone about Dr O'Donnell, he is so caring and listens very well
    • Patient Review

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      January 13th 2025
      Pleased
    • Patient Review

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      December 24th 2024
      Great staff wonderful kind caring answers question or concerns
    • Patient Review

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      December 24th 2024
      After discussing my primary concerns the doctor asked if I had any other concerns. I mentioned a completely different body area that had become painful recently He asked a few questions about the situation and said that since there were no X-rays of that joint there really wasn't anything to be done at the moment. No suggestions of steps to take were offered.It felt rather dismissive and was a bit frustrating. It was also incongruous to the rest of the visit which was very very attentive and helpful.
    • Patient Review

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      December 23rd 2024
      Both Dr. O'Donnell and his NP were great.
    • Patient Review

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      December 16th 2024
      Dr. O'Donnell very thorough, explained things well and took time to answer questions.
    • Patient Review

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      December 10th 2024
      Good
    • Patient Review

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      December 10th 2024
      Very happy with my decision to choose UK and Dr O'Donnell.
    • Patient Review

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      December 3rd 2024
      Good
    • Patient Review

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      November 19th 2024
      Very well informed in language I can relate to and understand. Listened to other issues I was having and was able to get referrals in and pull the Dr back in for a minute to ensure what I was describing, got sent to the proper specialist