Patrick O'Donnell received his medical and doctorate degrees from Indiana University School of Medicine, Indianapolis. He completed a residency in orthopaedic surgery at the University of Minnesota, Minneapolis. He then completed a fellowship in musculoskeletal oncology at the University of Toronto, Mt. Sinai Hospital, Princess Margaret Cancer Center, Toronto, Ontario, Canada.

O'Donnell is currently an Assistant Professor and the director of the Sarcoma Program at the University of Kentucky Markey Cancer Center.

Personal Statment

As an orthopaedic oncologist, I get to treat patients of every age. I operate on every bone in the body so I get many different surgeries, and it's made me a better surgeon. I treat many different types of cancers, including tumors that have started outside the bone and tumors that have spread inside the bone.

I help people by performing reconstructive surgery. We often help patients who have periprosthetic fractures with tumor-style prosthesis. Additionally, we are able to use many surgical techniques to help patients who don’t have cancer.

Patients who previously had no options for their hip or knee have options now. We can replace entire bones, including the femur, the biggest bone in the body. We can provide a cancer-style prosthesis that we connect with a knee replacement and a hip replacement and provide patients a new leg to walk on.

Faculty Rank

  • Associate Professor of Orthopaedics
  • fixes empty view field issue
    Patrick O'Donnell, MD, PhD - UK HealthCare
  • Podcast

    When to have a hip or knee replacement

    Dr. Patrick O'Donnell explains when hip and knee reconstruction might be the right option for patients.

  • Patient Story

    Suzanne Springate

    “My Knees have to be fantastic”

    Suzanne Springate was on her feet as a nurse for nearly 4 decades before retiring. During the last few years of her career, she lived with pain because she thought it might be a sign of weakness. When she finally realized she needed to have both of her knees replaced, she went to Patrick O’Donnell, MD, an orthopaedic surgeon who she knew through work.

    Read Suzanne Springate’s story »


Training & Education


Indiana University, School of Medicine, Indianapolis


University of Minnesota Medical Center, Minneapolis


University of Toronto, Mt. Sinai Hospital, Toronto, Ontario, Canada

Certifications and Special Training

American Board of Orthopaedic Surgery

Insurance Information

Insurance policies can vary widely. Please check with your doctor/clinic for specific insurance information before your visit or procedure to avoid unexpected out-of-pocket costs.

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