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Kentucky Children’s Hospital is now Golisano Children’s at UK.
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Specialties

Conditions

Procedures Performed

  • Cardiac Electrophysiology
  • Catheter ablation for atrial and ventricular arrhythmias
  • Implant and management of cardiovascular implantable electronic devices (pacemakers and defibrillators)
  • Lead extraction

Related Services

About

Dr. Karam Ayoub received his medical degree from Jordan University of Science and Technology in Jordan. He completed his internal medicine residency from University of Arkansas for Medical Sciences. This was followed by an internal medicine chief residency year from University of Arkansas for Medical Sciences. In 2017, Dr. Ayoub came to UK to complete a cardiovascular disease fellowship. Following that, Dr. Ayoub completed a fellowship in clinical cardiac electrophysiology from UK and Vanderbilt University Medical Center, with a focus on complex atrial and ventricular arrhythmias. In 2022, Dr. Ayoub returned to the cardiology team at UK HealthCare in the Heart Rhythm Program. In his spare time, Dr. Ayoub likes to spend his time playing soccer and baking with his kids.

Faculty Rank

  • Assistant Professor of Medicine

Training & Education

Degree

Jordan University of Science & Technology, School of Medicine, Irbid, Jordan

Residency

Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, Ark.

Fellowship

Cardiovascular Medicine, University of Kentucky, Lexington, Ky.
Clinical Cardiac Electrophysiology, University of Kentucky, Lexington, Ky.
Clinical Cardiac Electrophysiology, Vanderbilt University Medical Center, Nashville, Tenn.

Certifications and Special Training

American Board of Internal Medicine
American Board of Internal Medicine, Cardiovascular Disease
American Board of Internal Medicine, Clinical Cardiac Electrophysiology
National Board of Echocardiography

Ratings & Reviews

4.96 out of 5
50 Reviews

The star rating is a calculation based on feedback from our patients using our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more about our survey process. Responses are measured on a scale of 1 to 5 with 5 being the best score.

  • Patient Review

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    August 22nd 2025
    He listens to me

    Patient Review

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    August 22nd 2025
    This was my first visit with Dr. Ayoub - he was excellent! Kind, caring, and generous with his time. He took time to explain everything very thoroughly and listened in detail to discussions with the patient. I was very satisfied with him and his approach to handling the problem.

    Patient Review

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    August 20th 2025
    Dr. Ayoub was very proactive in suggesting tweaks to my pacemaker programs that would give me more energy. He explained them well and was pleased to hear that the adjustments he made to the pacemaker programming previously resulted in less fatigue during exertion.

    Patient Review

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    August 20th 2025
    Good experience

    Patient Review

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    August 13th 2025
    I do recommend to anyone I can

    • Patient Review

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      August 8th 2025
      I was very pleased with the insights shared!

    • Patient Review

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      August 8th 2025
      Dr Ayoub is great! So smart and kind. Listens well. So lucky to be in his care

    • Patient Review

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      July 30th 2025
      Dr Ayoub is very caring and concerned about my fears

    • Patient Review

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      July 30th 2025
      Very informative.

    • Patient Review

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      July 30th 2025
      DR AYOUB IS AN EXCELLENT DOCTOR. HE ALWAYS ANSWERS QUESTIONS VERY THOROUGHLY.

    • Patient Review

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      July 30th 2025
      Dr. Ayoub was very open to my questions and did an excellent job of answering them.

    • Patient Review

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      July 23rd 2025
      Dr. You is the best.

    • Patient Review

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      July 16th 2025
      Dr. Ayoub could teach a class on how to communicate with patients. He is amazing!

    • Patient Review

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      July 11th 2025
      Dr. Ayoub is wonderful about explaining things in an understandable way and he also is excellent at listening to one's concerns and encourages questions. He is really quite outstanding in this way.

    • Patient Review

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      July 11th 2025
      I have only seen him twice. He explains everything in detail great.

    • Patient Review

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      July 11th 2025
      Dr Ayoub was very informative with options for my treatment. He explained all options in great detail and was very clear that the decision needed to be made by me as to which option I decided on.

    • Patient Review

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      July 11th 2025
      Ayoub is fantastic so bright and personable

    • Patient Review

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      July 9th 2025
      No complaints.

    • Patient Review

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      July 8th 2025
      Good

    • Patient Review

      -
      July 2nd 2025
      Excellent experience

    • Patient Review

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      July 2nd 2025
      Dr. Ayoub provided excellent care and my results were above and beyond my expectations. I couldn't be happier.

    • Patient Review

      -
      June 27th 2025
      Dr Ayoub was very caring and warm. He took time to thoroughly explain my needed procedure and drew diagrams. He allowed me time to make a decision without feeling rushed. I highly recommend Dr Ayoub.

    • Patient Review

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      June 25th 2025
      I appreciate his concern about my troubling experiences trying to get a heart ablation done so I can get off of the harmful Meds to my lungs

    • Patient Review

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      June 25th 2025
      This physician is absolutely the best physician I have ever had to visit. He makes you feel calm and explains everything thoroughly. I absolutely recommend him and I am thankful for him.

    • Patient Review

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      May 21st 2025
      Good experience

    • Patient Review

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      May 7th 2025
      Dr Ayoub was very clear, answered all questions, explained several options- excellent experience

    • Patient Review

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      April 23rd 2025
      Good

    • Patient Review

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      April 23rd 2025
      A great deal of concern and consideration wasshown by the doctor and the PA.

    • Patient Review

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      April 23rd 2025
      Good experience

    • Patient Review

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      April 16th 2025
      Dr ayoub is. Very good. I

    • Patient Review

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      April 16th 2025
      Dr Ayoub is the absolute best!!!

    • Patient Review

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      March 28th 2025
      Had the best visit yet.

    • Patient Review

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      March 28th 2025
      Doctor was very interested in my concerns and gave me confidence in his recommendation.

    • Patient Review

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      March 26th 2025
      Dr. Ayoub is extraordinarily compassionate. I have never been more impressed by or comfortable with a physician. He restored my heart health.

    • Patient Review

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      March 19th 2025
      Dr. Ayoub and his staff are always thorough and polite. They always show me the upmost care and kindness.

    • Patient Review

      -
      March 19th 2025
      5 *****

    • Patient Review

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      March 14th 2025
      Dr Ayoub was very thorough in our discussions regarding treatment options, ways to Imprrove my health at home, as well as information about improving my daily quality of life.

    • Patient Review

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      March 12th 2025
      I have been dealing with with UK since an accident in 2001 for various problems. I have the utmost respect and confidence in all the staff at UK.

    • Patient Review

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      March 5th 2025
      Dr. Ayoub listens, asks questions to clarify, explains all treatment options and values my opinion. Wonderful provider!

    • Patient Review

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      February 26th 2025
      Dr. Ayoub is kind, caring, and really listens. It's obvious he wants to help his patient feel better and have good quality of life. He's an excellent doctor.

    • Patient Review

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      February 26th 2025
      Never had a visit so educating, thorough, professional and caring

    • Patient Review

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      February 26th 2025
      Very good listener. Bedside manner was exceptional. Felt very comfortable with Dr. Ayoub.

    • Patient Review

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      February 14th 2025
      Felt very comfortable talking with the doctor

    • Patient Review

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      February 14th 2025
      Extremely through with all treatment options and reassuring about actions I should take if problem reoccurs.

    • Patient Review

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      February 5th 2025
      The Dr took time to talk to me resulting in a change of medication and I feel great.

    • Patient Review

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      January 22nd 2025
      This was my first appt with Dr Ayoub. I was a patient of A. Hesselson previously. I don't believe I have ever had a new physician who had reviewed my case so throughly. He had totally reviewed my history the prior evening. Had questions for me which made me realize he had a total understanding of my disease process and treatment over past 4 years. He explained with drawings exactly what is occurring in my heart and treatment I had so far received. We also discussed the reality that the AFib and flutter will most likely return in next 10 years and discussed plan of care when it does. Discussed options and he included me in all decision making. He addressed my current problem of severe fatigue with medication discontinuation gradually. I was so apprehensive about having a new EP cardio doc but I believe Dr Ayoub is the answer to prayer. I was so impressed and feel very secure with my continued care.

    • Patient Review

      -
      January 22nd 2025
      Spot on what I need and options I had

    • Patient Review

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      January 22nd 2025
      HAD NOTHING BUT THE BEST OF CARE AS USUAL

    • Patient Review

      -
      January 16th 2025
      I was very happy with visit

    • Patient Review

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      January 16th 2025
      Doctor was very nice and understanding