William H. St. Clair, MD, PhD

  • Co-Director, Gamma Knife® Radiosurgery Center
4.8 out of 5


William H. St. Clair, MD, PhD, is a professor in the Department of Radiation Oncology at the University of Kentucky. Since coming to UK in 2000, he has served as Residency Director, Assistant and Associate Professor, and Interim Chairman for the department, as well as taking on a joint appointment in the Graduate Center for Nutritional Sciences. Dr. St. Clair previously worked as Assistant Professor of Radiology at the Bowman Gray School of Medicine at Wake Forest University, a Research Fellow in the Department of Cancer Biology, Laboratory of Radiobiology, at the Harvard School of Public Health, a Cancer Center Research Assistant at the University of Iowa, and as a Quality Control Chemist at First Mississippi Inc.

Dr. St. Clair completed his residency in radiation oncology at Massachusetts General Hospital and interned in the Department of Internal Medicine at The Christ Hospital in Cincinnati, Ohio. He earned his BS in Biology at St. Ambrose College, his MS and PhD in Radiation Biology at the University of Iowa, and his MD at UK. Dr. St. Clair is certified in radiation oncology by the American Board of Radiology and is a member of several professional medical societies.

Having served on many board committees, Dr. St. Clair has also been a part of many published research articles and has presented on their findings at myriad societal meetings across his more than 30-year career. His clinical interested include genitourinary and central nervous system neoplasms.

Outside of medicine, Dr. St. Clair enjoys taking hikes, particularly in state parks, and he considers himself an avid gardener.

Personal Statement: “What I like best about being in radiation oncology is two-fold: the technology is very interesting. It’s fast-moving and continuing to improve every day. And I really enjoy the very frequent patient contact. I get to see patients every day and share treatment successes with them. When I have a patient initially come to see me in a wheelchair due to the tremendous amount of pain they’re in and then get to see them up and walking after just two or three treatment sessions—it’s a very rewarding part of my job.”

Faculty Rank

  • Professor of Radiation Medicine
  • fixes empty view field issue
    Multi-disciplinary team and Gamma Knife

Training & Education


MD, University of Kentucky, College of Medicine, Lexington
PhD, University of Iowa, College of Medicine, Iowa City


Massachusetts General Hospital, Boston


Harvard University Medical Center, Boston

Certifications and Special Training

American Board of Radiology, Radiation Oncology

Insurance Information

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Ratings & Reviews

4.8 out of 5
5 Reviews

The star rating is a calculation based on feedback from our patients using our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more about our survey process. Responses are measured on a scale of 1 to 5 with 5 being the best score.

  • Patient Review


    Patient Review

    I feel there were more options out there?

    Patient Review

    Everything was great

    Patient Review

    Very pleased with everyone.

    Patient Review

    Outstanding clinic!