Patrick O'Donnell received his medical and doctorate degrees from Indiana University School of Medicine, Indianapolis. He completed a residency in orthopaedic surgery at the University of Minnesota, Minneapolis. He then completed a fellowship in musculoskeletal oncology at the University of Toronto, Mt. Sinai Hospital, Princess Margaret Cancer Center, Toronto, Ontario, Canada.
O'Donnell is currently an Assistant Professor and the director of the Sarcoma Program at the University of Kentucky Markey Cancer Center.
As an orthopaedic oncologist, I get to treat patients of every age. I operate on every bone in the body so I get many different surgeries, and it's made me a better surgeon. I treat many different types of cancers, including tumors that have started outside the bone and tumors that have spread inside the bone.
I help people by performing reconstructive surgery. We often help patients who have periprosthetic fractures with tumor-style prosthesis. Additionally, we are able to use many surgical techniques to help patients who don’t have cancer.
Patients who previously had no options for their hip or knee have options now. We can replace entire bones, including the femur, the biggest bone in the body. We can provide a cancer-style prosthesis that we connect with a knee replacement and a hip replacement and provide patients a new leg to walk on.
Faculty RankAssociate Professor of Orthopaedics
Indiana University, School of Medicine, Indianapolis
University of Minnesota Medical Center, Minneapolis
University of Toronto, Mt. Sinai Hospital, Toronto, Ontario, Canada
Certifications and Special Training
American Board of Orthopaedic Surgery
When to have a hip or knee replacement
Dr. Patrick O'Donnell explains when hip and knee reconstruction might be the right option for patients.
“My Knees have to be fantastic”
Suzanne Springate was on her feet as a nurse for nearly 4 decades before retiring. During the last few years of her career, she lived with pain because she thought it might be a sign of weakness. When she finally realized she needed to have both of her knees replaced, she went to Patrick O’Donnell, MD, an orthopaedic surgeon who she knew through work.
UK Markey Cancer CenterWhitney-Hendrickson Building800 Rose St.
Lexington, KY 40536
A parking lot is located near the Whitney-Hendrickson Building, accessible via Hospital Drive. Get directions to Whitney-Hendrickson.
UK Orthopaedic Surgery & Sports Medicine
UK Orthopaedic Surgery & Sports Medicine: Hip & Knee Treatment
UK Good Samaritan Medical Office Building125 E. Maxwell St.
Lexington, KY 40508
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