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Joseph (Jay) B. Zwischenberger, MD, FACS

Joseph (Jay) B.  Zwischenberger, MD, FACS
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  • Cardiovascular & Thoracic Surgery
  • Extracorporeal Membrane Oxygenation (ECMO)
  • Lung and Thoracic Cancer Team
  • About

    Dr. Jay Zwischenberger plays the harmonica as part of music therapy.
    Dr. Jay Zwischenberger plays the harmonica as part of music therapy.

    Joseph Zwischenberger received his medical degree from the University of Kentucky, College of Medicine. He completed residencies in General Surgery and Cardiothoracic Surgery. He completed a Critical Care/ECMO fellowship at the University of Michigan Health System, Ann Arbor, Mich. He also completed a Cardiac Surgery fellowship at the National Institutes of Health.

    Dr. Zwischenberger is board certified by the American Board of Surgery and Surgical Critical Care and the American Board of Thoracic Surgery.

    Faculty Rank

    Professor of Surgery and Pediatrics


    University of Kentucky, College of Medicine


    University of Michigan Health System, Ann Arbor


    Critical Care/ECMO, University of Michigan Health System, Ann Arbor

    Cardiac Surgery, National Institute of Health

    Certifications and Special Training

    American Board of Surgery

    American Board of Surgery, Surgical Critical Care

    American Board of Thoracic Surgery

  • Publications

    1. Wang-Zwische double lumen cannula-toward a percutaneous and ambulatory paracorporeal artificial lung. Wang D, Zhou X, Liu X, Sidor B, Lynch J, Zwischenberger JB. ASAIO J. 2008 Nov-Dec;54(6):606-11. doi: 10.1097/MAT.0b013e31818c69ab. PMID: 19033774
    2. Artificial lung basics: fundamental challenges, alternative designs and future innovations. Nolan H, Wang D, Zwischenberger JB. Organogenesis. 2011 Jan-Mar;7(1):23-7. Epub 2011 Jan 1. Review. PMID: 21289479
    3. Physiologic response to a simplified venovenous perfusion-induced systemic hyperthermia system. Ballard-Croft C, Wang D, Jones C, Sumpter LR, Zhou X, Thomas J, Topaz S, Zwischenberger JB. ASAIO J. 2012 Nov-Dec;58(6):601-6. doi: 10.1097/MAT.0b013e318271badb. PMID: 23085942
  • Research

    Cancer Center Member

    Research Focus

    Development of an artificial lung; development of hyperthermia as a therapy for lung cancer; development of the double lumen cannula for use in ambulatory extracorporeal membrane oxygenation and potential use in other therapies.


    • Translational Oncology

    College & Department

    • College of Medicine
    • Department of Surgery

    For Referring Physicians

    800 Rose Street, MN264
    Lexington, KY 40536-0298
    United States

  • Locations

    Multidisciplinary Clinic

    Multidisciplinary Clinic

    Whitney Hendrickson Building
    UK Markey Cancer Center
    Whitney-Hendrickson Building
    800 Rose St.
    First Floor
    Lexington, KY 40536

    A parking lot is located near the Whitney-Hendrickson Building, accessible via Hospital Drive. Get directions to Whitney-Hendrickson.

    Cardiovascular & Thoracic (CT) Surgery

    Cardiovascular & Thoracic Surgery Clinic

    Kentucky Clinic building
    Kentucky Clinic
    740 S. Limestone
    Third Floor, Room L300
    Lexington, KY 40536
    Monday - Friday: 8:30 am-5:00 pm

    Clinic times vary per physician 
    After Hours contact: 859-257-1000

    Insurance Information

    Insurance policies can vary widely. Please check with your doctor/clinic for specific insurance information before your visit or procedure to avoid unexpected out-of-pocket costs. See list of insurers Arrow Pointing Right

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