Oleg Tsodikov, PhD

About

Faculty Rank

  • Associate Professor

Research

Research Focus

Mechanistic studies of oncogenic transcription factors and their disruption in search for novel anti-cancer therapeutics.

Contact Information

789 S. Limestone St.
Lexington, KY 40536
United States

Phone

Publications

  1. Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1.
    Hou C, Weidenbach S, Cano KE, Wang Z, Mitra P, Ivanov DN*, Rohr J* and Tsodikov OV* (2016) Nucleic Acids Res., 44, 8990-9004.
  2. Dimerization and DNA recognition rules of mithramycin and its analogues.
    Weidenbach S, Hou C, Chen J-M, Tsodikov OV* and Rohr J* (2016) J. Inorg. Biochem.,156, 40-47.
  3. Structural basis for dimerization and DNA binding of transcription factor FLI1.
    Hou C and Tsodikov OV (2015) Biochemistry,54, 7365-7374.
  4. Structural basis for the recruitment of ERCC1-XPF to nucleotide excision repair complexes by XPA.
    Tsodikov OV† , Ivanov D† , Orelli B, Staresincic L, Shoshani I, Oberman R, Schärer OD, Wagner G and Ellenberger T* (2007) EMBO J., 26, 4768-4776.
  5. Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1.
    Tsodikov OV, Enzlin JH, Scharer OD and Ellenberger T* (2005) Proc. Natl. Acad. Sci. U. S. A., 102, 11236-11241.