About

Faculty Rank

  • Associate Professor

Research

Research Focus

  • Epigenetic regulation of lung inflammation and carcinogenesis by environmental factors.
  • Critical Care Medicine.
  • Lung, kidney and vascular inflammation, injury and repair; Innate Immunity.

Programs

Molecular and Cellular Oncology

College & Department

Contact Information

789 S. Limestone
Lexington, KY 40536
United States

Phone
859-218-1029
Email
jian.fu@uky.edu

Publications

  1. Selective HDAC6 inhibition prevents TNF-α-induced lung endothelial cell barrier disruption and endotoxin-induced pulmonary edema
    Yu J, Ma Z, Shetty S, Ma M, Fu J. American Journal of Physiology- Lung Cellular and Molecular Physiology, 2016 May 17:ajplung.00051.2016. doi: 10.1152/ajplung.00051.2016.
  2. Sirt1 restrains lung inflammasome activation in a murine model of sepsis.
    Gao R., Chen J., Hu Y., Shetty S., Ma Z., Fu J. American Journal of Physiology- Lung Cellular and Molecular Physiology 308(8):L847-53, 2015.
  3. Sirt1 protects against thrombomodulin down-regulation and lung coagulation after particulate matter exposure
    Wu Z., Liu M., Liang M., Fu J. Blood 119(10):2422-29, 2012.
  4. LOX-1 deletion improves neutrophil function, enhances bacterial clearance and reduces lung injury in a murine polymicrobial sepsis model.
    Wu Z., Sawamura T., Kurdowska AK., Ji HL., Idell S., Fu J. Infection and Immunity 79(7):2865-2870, 2011.
  5. Blockade of LOX-1 prevents endotoxin-induced lung inflammation and injury in mice.
    Zhang P., Cheng L., Liang M., Liu MC. Fu J. Journal of Innate Immunity 1(4):358-365, 2009.