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Pediatric Specialty Infusion Clinic (monoclonal antibody therapy)


The Kentucky Children’s Hospital Specialty Infusion Clinic serves as the primary state site for pediatric COVID-19 monoclonal antibody infusions for children ages 12 to 17. These infusions mimic and supplement the body’s immune response, making it harder for the virus to spread and progress to a severe infection, reducing the risk of hospitalization.

Monoclonal antibodies, which are available under emergency use authorization (EUA) from the U.S. Food & Drug Administration, are similar to the antibodies your immune system would produce in response to an infection. They are mass-produced artificial antibodies that are designed to target the coronavirus. Read more about monoclonal antibodies: FDA fact sheet.

The therapy is used to bolster the body’s own immune system to fight the virus but is not meant to replace the COVID-19 vaccine. Vaccination for kids 12 and older is recommended as the first line of defense against COVID.

  • Treatment eligibility

    Children ages 12 to 17 who test positive for COVID or have had a known exposure are eligible to receive infusions if they have high-risk factors that increase the chance of a negative outcome. (Children must weigh at least 40 kg – about 88 pounds – to receive an infusion.) High-risk factors include:

    • Obesity or being overweight (body mass index greater than 85 percent for their age and gender on CDC growth charts)
    • Chronic kidney disease
    • Diabetes
    • Immunosuppressive disease or immunosuppressive treatment
    • Cardiovascular disease, including congenital heart disease
    • Sickle cell disease
    • Pregnancy
    • Chronic lung disease including moderate to severe asthma, interstitial lung disease, cystic fibrosis and pulmonary hypertension
    • Neurodevelopmental disorders such as cerebral palsy, genetic/metabolic syndromes, severe congenital anomalies
    • Patients who are dependent on medical technology such as tracheostomy, gastrostomy, positive pressure ventilation not related to COVID-19

    Patients require only one infusion, which takes about 30 minutes, but should expect to spend about three hours at the clinic.

  • Patient referrals

    Patients are accepted by referral only. Please contact your primary care provider for a referral. To refer a patient or learn more about patient eligibility, providers may reference this form.

    After a referral has been made, the clinic will call the patient to schedule an appointment and provide directions to the clinic. 

The Specialty Infusion Clinic is a hospital-based clinic. Learn more about UK HealthCare's other hospital-based clinics and departments online.

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Hours of operation: 3 p.m.-9 p.m., Monday through Friday.