The Kentucky Children’s Hospital Specialty Infusion Clinic serves as the primary state site for pediatric COVID-19 monoclonal antibody infusions for children ages 12 to 17. These infusions mimic and supplement the body’s immune response, making it harder for the virus to spread and progress to a severe infection, reducing the risk of hospitalization.
Monoclonal antibodies, which are available under emergency use authorization (EUA) from the U.S. Food & Drug Administration, are similar to the antibodies your immune system would produce in response to an infection. They are mass-produced artificial antibodies that are designed to target the coronavirus. Read more about monoclonal antibodies: FDA fact sheet.
The therapy is used to bolster the body’s own immune system to fight the virus but is not meant to replace the COVID-19 vaccine. Vaccination for kids 12 and older is recommended as the first line of defense against COVID.
Children ages 12 to 17 who test positive for COVID or have had a known exposure are eligible to receive infusions if they have high-risk factors that increase the chance of a negative outcome. (Children must weigh at least 40 kg – about 88 pounds – to receive an infusion.) High-risk factors include:
- Obesity or being overweight (body mass index greater than 85 percent for their age and gender on CDC growth charts)
- Chronic kidney disease
- Immunosuppressive disease or immunosuppressive treatment
- Cardiovascular disease, including congenital heart disease
- Sickle cell disease
- Chronic lung disease including moderate to severe asthma, interstitial lung disease, cystic fibrosis and pulmonary hypertension
- Neurodevelopmental disorders such as cerebral palsy, genetic/metabolic syndromes, severe congenital anomalies
- Patients who are dependent on medical technology such as tracheostomy, gastrostomy, positive pressure ventilation not related to COVID-19
Patients require only one infusion, which takes about 30 minutes, but should expect to spend about three hours at the clinic.
As the primary state site for pediatric monoclonal antibody infusions, the Specialty Infusion Clinic at Kentucky Children’s Hospital offers a state-of-the-art clinic tailored to serving the needs of young patients. Located in UK HealthCare’s Kentucky Clinic, this clinic can provide infusion therapy to up to 26 pediatric patients per day. The clinic has 13 infusion spaces with two rooms that can accommodate siblings.
Patients are accepted by referral only. Please contact your primary care provider for a referral. To refer a patient or learn more about patient eligibility, providers may reference this form.
After a referral has been made, the clinic will call the patient to schedule an appointment and provide directions to the clinic.
The Specialty Infusion Clinic is a hospital-based clinic. Learn more about UK HealthCare's other hospital-based clinics and departments online.
Hours of operation: 3 p.m.-9 p.m., Monday through Friday.