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Rolf Craven, PhD

Cancer Center Member

rolf craven

Research Programs:
Molecular and Cellular Oncology

Colleges & Departments:
College of Medicine, Department of Pharmacology and Nutritional Sciences

Faculty Rank:
Associate Professor

Research Focus

Lung cancer, signaling, autophagy.

Contact Information

University of Kentucky
Lexington, KY 40536
United States



  1. Pgrmc1 (progesterone receptor membrane component 1) associates with EGFR and regulates erlotinib sensitivity. Ahmed IS, Rohe HJ, Twist KE and Craven RJ. J Biol Chem 285:24775-24782, 2010.
  2. Ngal (neutrophil gelatinase-associated lipocalin) transcription dependent on the tumor-associated sigma-2 receptor S2RPgrmc1. Mir SUR, Jin L and Craven RJ. J Biol Chem 287:14494-501, 2012.
  3. Elevated Pgrmc1 (progesterone receptor membrane component 1)/sigma-2 receptor levels in lung tumors and plasma from lung cancer patients. Mir SUR, Ahmed IS, Arnold S and Craven RJ. Int J Cancer 131:1-9, 2012.
  4. The Rak/Frk tyrosine kinase associates with and internalizes the epidermal growth factor receptor. Jin L and Craven RJ. Oncogene, epub Jan 14, 2013.
  5. Sigma-2 receptor associates with MAP1-LC3B and promotes autophagy. Mir SUR, Schwarze S, Jin L, Zhang J, Friend W, Miriyala S, St Clair D and Craven RJ. Autophagy 2013.


Research Equipment