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Robert S. DiPaola, MD

Cancer Center Member

Dean, University of Kentucky College of Medicine

Dr. Robert DiPaola

Research Programs:
Translational Oncology

Colleges & Departments:
College of Medicine, Department of Internal Medicine

Faculty Rank:
Professor of Medicine

Research Focus

Drug Resistance in Cancer Therapy - preclinical studies that support translational clinical trials and investigations into prostate cancer drug resistance.

Contact Information

800 Rose Street
MN 150
Lexington, KY 40536-0298
United States


  1. Atg7 cooperates with Pten loss to drive prostate cancer growth. Santanam U, Banach-Petrosky W, Abate-Shen C, Shen MM, White E, and DiPaola RS. Genes & Development. 2016 Feb 15;30(4):399-407. PubMed PMID: 26883359; PubMed Central PMCID: PMC4762425.
  2. Chemohormonal Therapy in Metastatic Hormone-Sensitive Prostate Cancer. Sweeney CJ, Chen YH, Carducci M, Liu G, Jarrard DF, Eisenberger M, Wong YN, Hahn N, Kohli M, Cooney MM, Dreicer R, Vogelzang NJ, Picus J, Shevrin D, Hussain M, Garcia JA, DiPaola RS. N Engl J Med. 2015 Aug 20; 373(8):737-46. Epub 2015 Aug 5. PMID: 26244877.
  3. Survival following primary androgen deprivation therapy among men with localized prostate cancer. Lu-Yao GL, Albertsen PC, Moore DF, Shih W, Lin Y, DiPaola RS and Yao SL. JAMA. 2008 Jul 9;300(2):173-81. PubMed PMID: 18612114; PubMed Central PMCID: PMC2645653.
  4. Phase I trial of weekly docetaxel with concurrent three-dimensional conformal radiation therapy in the treatment of unfavorable localized adenocarcinoma of the prostate. Kumar P, Perrotti M, Weiss R, Todd M, Goodin S Cummings K and DiPaola RS. J Clin Oncol. 2004 May 15;22(10):1909-15. PubMed PMID: 15143084.
  5. Clinical and biologic activity of an estrogenic herbal combination (PC-SPES) in prostate cancer. DiPaola RS, Zhang H, Lambert GH, Meeker R, Licitra E, et al. N Engl J Med. 1998 Sep 17;339(12):785-91. PubMed PMID: 9738085.



University of Utah, Salt Lake City


Duke University Medical Center, Durham, N.C.


Hematology and Oncology, University of Pennsylvania, School of Medicine, Philadelphia

Certifications and Special Training

American Board of Internal Medicine

Certifications and Special Training

American Board of Internal Medicine, Medical Oncology

Research Equipment