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Rina Plattner, PhD

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rina plattner
  • About

    Faculty Rank

    Professor
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  • Publications

    1. c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways, and drive metastatic progression. Ganguly SS, Fiore LS, Sims JT, Friend JW, Srinivasan D, Cibull ML, Wang Ch, Novak M, Kaetzel, DM, Plattner R. Oncogene 31:1804-1816, 2012.
    2. Deregulated abl kinases promote proliferation, anchorage-independent growth and survival of aggressive breast cancer cells. Srinivasan D, Sims JT, Plattner R. Oncogene 27:1095-1105, 2008.
    3. SHP-2 is a novel target of Abl kinases during cell proliferation. Mitra S, Beach C, Feng GS, Plattner R. J Cell Sci 121:3335-3346, 2008.
    4. Imatinib reverses doxorubicin resistance by affecting activation of STAT3-dependent NF-κΒ and HSP27/p38/AKT pathways and by inhibiting ABCB1. Sims JT, Ganguly SS, Bennett H, Friend WJ, Tepe J, Plattner R. PLoS One 2013.
  • Research

    Cancer Center Member

    Research Focus

    Abl non-receptor tyrosine kinases, cancer invasion.

    Programs

    • Cancer Cell Biology and Signaling

    College & Department

    • College of Medicine
    • Department of Pharmacology and Nutritional Sciences

    For Referring Physicians

    209 Combs Building
    University of Kentucky
    Lexington, KY 40536
    United States

    Phone
    859-323-4778