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Oleg Tsodikov, PhD

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  • About

    Faculty Rank

    Associate Professor
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  • Publications

    1. Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1. Hou C, Weidenbach S, Cano KE, Wang Z, Mitra P, Ivanov DN*, Rohr J* and Tsodikov OV* (2016) Nucleic Acids Res., 44, 8990-9004.
    2. Dimerization and DNA recognition rules of mithramycin and its analogues. Weidenbach S, Hou C, Chen J-M, Tsodikov OV* and Rohr J* (2016) J. Inorg. Biochem.,156, 40-47.
    3. Structural basis for dimerization and DNA binding of transcription factor FLI1. Hou C and Tsodikov OV (2015) Biochemistry,54, 7365-7374.
    4. Structural basis for the recruitment of ERCC1-XPF to nucleotide excision repair complexes by XPA. Tsodikov OV† , Ivanov D† , Orelli B, Staresincic L, Shoshani I, Oberman R, Schärer OD, Wagner G and Ellenberger T* (2007) EMBO J., 26, 4768-4776.
    5. Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1. Tsodikov OV, Enzlin JH, Scharer OD and Ellenberger T* (2005) Proc. Natl. Acad. Sci. U. S. A., 102, 11236-11241.
  • Research

    Cancer Center Member

    Research Focus

    Mechanistic studies of oncogenic transcription factors and their disruption in search for novel anti-cancer therapeutics.

    Programs

    • Drug Discovery, Delivery and Translational Therapeutics

    College & Department

    • College of Pharmacy
    • Department of Pharmaceutical Sciences

    For Referring Physicians

    789 S. Limestone St.
    Lexington, KY 40536
    United States

    Phone
    859-218-1687