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Michael G. Fried, PhD

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mike fried
  • About

    Faculty Rank

    Professor
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  • Publications

    1. Equilibria and Kinetics of Lac Repressor-Operator Interactions by Polyacrylamide Gel Electrophoresis. Fried MG and Crothers DM. Nucl Acids Re. 9:6505-6525, 1981.
    2. DNA Looping and Lac Repressor-CAP Interaction. Fried MG and Hudson JM. Science 274:1930-1931, 1996.
    3. Flipping of alkylated DNA damage bridges base and nucleotide excision repair. Tubbs JL, Butt S, Kanugula M, Melikishvili M, Marriott A, Watson AJ, Verbeek B, Santibanez-Koref MF, Kraehenbuehl R, Fleck O, Millington C, Arvai AS, Kroeger MD, Peterson LA, Williams DM, Fried MG, Margison GP, Pegg AE and Tainer JA. Nature 459:808-813, 2009.
    4. Topologies Of Complexes Containing O6-Alkylguanine-DNA-Alkyltransferase And DNA. Adams CA, Melikishvili M, Rodgers DW, Rasimas JJ, Pegg AE and Fried MG. Journal of Molecular Biology, 389:248-263, 2009.
    5. Mutations That Probe The Cooperative Assembly Of O6-Alkylguanine-DNA Alkyltransferase (AGT) Complexes. Adams CA and Fried MG. Biochemistry 50:1590-1598, 2011.
  • Research

    Cancer Center Member

    Research Focus

    DNA repair, mutagenesis, chemotherapy.

    Programs

    • Genomic Instability, Epigenetics and Metabolism

    College & Department

    • College of Medicine
    • Department of Molecular and Cellular Biochemistry

    For Referring Physicians

    259-B BBSRB
    741 S. Limestone, University of Kentucky
    Lexington, KY 40502
    United States

    Phone
    859-323-1205