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Selected BB SRF Publications 2010 - 2015


1.         Arnold SMRinehart JJ, Tsakalozou E, Eckardt JR, Fields SZ, Shelton BJ, DeSimone PA, Kee BK, Moscow JA and Leggas M. A phase I study of 7-t-butyldimethylsilyl-10-hydroxycamptothecin in adult patients with refractory or metastatic solid malignancies. Clin Cancer Res 16(2): 673-680, 2010. 

2.         Chen L, Lin DY and Zeng DL. Attributable fraction functions for censored event times. Biometrika 97(3): 713-726, 2010. 

3.          Feng H, Guo L, Song Z, Gao H, Wang D, Fu W, Han J, Li Z, Huang B and Li X-A. Caveolin-1 Protects against Sepsis by Modulating Inflammatory Response, Alleviating Bacterial Burden, and Suppressing Thymocyte Apoptosis. Journal of Biological Chemistry 285(33): 25154-25160, 2010. 

4.          Gal TJ, Shinn J and Huang B. Current epidemiology and management trends in acoustic neuroma. Otolaryngol Head Neck Surg 142(5): 677-681, 2010. 

5.          Gregory KJ, Zhao B, Bielenberg DR, Dridi S, Wu J, Jiang W, Huang B, Pirie-Shepherd S and Fannon M. Vitamin D binding protein-macrophage activating factor directly inhibits proliferation, migration, and uPAR expression of prostate cancer cells. PLoS One5(10): e13428, 2010. 

6.          Hade EM, Murray DM, Pennell ML, Rhoda D, Paskett ED, Champion VL, Crabtree BF, Dietrich A, Dignan MB, Farmer M, Fenton JJ, Flocke S, Hiatt RA, Hudson SV, Mitchell M, Monahan P, Shariff-Marco S, Slone SL, Stange K, Stewart SL and Strickland PA. Intraclass correlation estimates for cancer screening outcomes: estimates and applications in the design of group-randomized cancer screening studies. J Natl Cancer Inst Monogr2010(40): 97-103, 2010. 

7.          Hudspeth MP, Hill TN, Lewis JA, Van Meter E and Ragucci D. Post-hematopoietic stem cell transplant immunization practices in the Pediatric Blood and Marrow Transplant Consortium. Pediatr Blood Cancer 54(7): 970-975, 2010. 

8.          Johnson SM, Gulhati P, Rampy BA, Han Y, Rychahou PG, Doan HQ, Weiss HLand Evers BM. Novel expression patterns of PI3K/Akt/mTOR signaling pathway components in colorectal cancer. J Am Coll Surg 210(5): 767-776, 776-768, 2010. 

9.         Van Meter E, Lawson A, Colabianchi N, Nichols M, Hibbert J, Porter D and Liese A. An evaluation of edge effects in nutritional accessibility and availability measures: a simulation study. International Journal of Health Geographics9(1): 40, 2010. 

10.      Vanderpool RC and Huang B. Cancer risk perceptions, beliefs, and physician avoidance in Appalachia: results from the 2008 HINTS Survey. J Health Commun 15 Suppl 3: 78-91, 2010. 

11.       Waterstrat A, Liang Y, Swiderski CF, Shelton BJ and Van Zant G. Congenic interval of CD45/Ly-5 congenic mice contains multiple genes that may influence hematopoietic stem cell engraftment. Blood115(2): 408-417, 2010. 


12.       Christian WJ, Huang BRinehart J and Hopenhayn C. Exploring geographic variation in lung cancer incidence in Kentucky using a spatial scan statistic: elevated risk in the Appalachian coal-mining region. Public Health Rep 126(6): 789-796, 2011. 

13.       Dragun AE, Huang BTucker TC and Spanos WJ. Disparities in the application of adjuvant radiotherapy after breast-conserving surgery for early stage breast cancer: impact on overall survival. Cancer117(12): 2590-2598, 2011. 

14.      Fleming ST, Sabatino SA, Kimmick G, Cress R, Wu X-C, Trentham-Dietz A, Huang B, Hwang W and Liff J. Developing a Claim-based Version of the ACE-27 Comorbidity Index: A Comparison With Medical Record Review. Medical Care49(8): 752-760 2011. 

15.       Gal TJ, Silver N and Huang B. Demographics and treatment trends in sinonasal mucosal melanoma. Laryngoscope121(9): 2026-2033, 2011. 

16.       Gulhati P, Bowen KA, Liu J, Stevens PD, Rychahou PG, Chen M, Lee EYWeiss HLO'Connor KLGao T and Evers BM. mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways. Cancer Res 71(9): 3246-3256, 2011. 

17.       Johnson N, Shelton BJHopenhayn CTucker TT, Unrine JM, Huang B, Christian W, Zhang ZShi X and Li L. Concentrations of arsenic, chromium, and nickel in toenail samples from Appalachian Kentucky residents. J Environ Pathol Toxicol Oncol30(3): 213-223, 2011. 

18.       Li J, Liu J, Song J, Wang X, Weiss HL, Townsend CM, Jr., Gao T and Evers BM. mTORC1 inhibition increases neurotensin secretion and gene expression through activation of the MEK/ERK/c-Jun pathway in the human endocrine cell line BON. Am J Physiol Cell Physiol 301(1): C213-226, 2011. 

19.      Lutz CT, Karapetyan A, Al-Attar A, Shelton BJ, Holt KJ, Tucker JH and Presnell SR. Human NK cells proliferate and die in vivo more rapidly than T cells in healthy young and elderly adults. J Immunol 186(8): 4590-4598, 2011. 

20.      Massarweh S, Tham YL, Huang J, Sexton K, Weiss H, Tsimelzon A, Beyer A, Rimawi M, Cai WY, Hilsenbeck S, Fuqua S and Elledge R. A phase II neoadjuvant trial of anastrozole, fulvestrant, and gefitinib in patients with newly diagnosed estrogen receptor positive breast cancer. Breast Cancer Res Treat 129(3): 819-827, 2011. 

21.       Silva SR, Bowen KA, Rychahou PG, Jackson LN, Weiss HLLee EY, Townsend CM, Jr. and Evers BM. VEGFR-2 expression in carcinoid cancer cells and its role in tumor growth and metastasis. Int J Cancer 128(5): 1045-1056, 2011. 

22.       Silva SR, Zaytseva YY, Jackson LN, Lee EYWeiss HL, Bowen KA, Townsend CM, Jr. and Evers BM. The effect of PTEN on serotonin synthesis and secretion from the carcinoid cell line BON. Anticancer Res 31(4): 1153-1160, 2011. 

23.       Stults D, Killen M, Shelton Band Pierce A. Recombination phenotypes of the NCI-60 collection of human cancer cells. BMC Molecular Biology12(1): 23, 2011. 

24.      Van Meter E, Lawson AB, Colabianchi N, Nichols M, Hibbert J, Porter D and Liese AD. Spatial accessibility and availability measures and statistical properties in the food environment. Spatial and Spatio-temporal Epidemiology2(1): 35-47, 2011. 

25.      van Nagell JRJMiller RW, DeSimone CP, Ueland FR, Podzielinski I, Goodrich ST, Elder JW, Huang B, Kryscio RJ and Pavlik EJ. Long-Term Survival of Women With Epithelial Ovarian Cancer Detected by Ultrasonographic Screening. Obstetrics & Gynecology 118(6): 1212-1221, 2011. 

26.      Wang C, Tan ZQ and Louis TA. Exponential tilt models for two-group comparison with censored data. Journal of Statistical Planning and Inference 141(3): 1102-1117, 2011. 

27.       Wang Q, Zhou Y, Weiss HL, Chow CW and Evers BM. NFATc1 regulation of TRAIL expression in human intestinal cells. PLoS One6(5): e19882, 2011. 

28.       Wang X, Gulhati P, Li J, Dobner PR, Weiss H, Townsend CM, Jr. and Evers BM. Characterization of promoter elements regulating the expression of the human neurotensin/neuromedin N gene. J Biol Chem 286(1): 542-554, 2011. 

29.      Zhang Z, Wang X, Cheng S, Sun L, Son YO, Yao H, Li W, Budhraja A, Li L, Shelton BJTucker TArnold SM and Shi X. Reactive oxygen species mediate arsenic induced cell transformation and tumorigenesis through Wnt/beta-catenin pathway in human colorectal adenocarcinoma DLD1 cells. Toxicol Appl Pharmacol 256(2): 114-121, 2011. 

30.       Zhao Y, Burikhanov R, Brandon J, Qiu S, Shelton BJSpear BBondada S, Bryson S and Rangnekar VM. Systemic Par-4 inhibits non-autochthonous tumor growth. Cancer Biol Ther 12(2): 152-157, 2011. 


31.       Barone E, Cenini G, Sultana R, Di Domenico F, Fiorini A, Perluigi M, Noel T, Wang C, Mancuso C, St Clair DKand Butterfield DA. Lack of p53 Decreases Basal Oxidative Stress Levels in the Brain Through Upregulation of Thioredoxin-1, Biliverdin Reductase-A, Manganese Superoxide Dismutase, and Nuclear Factor Kappa-B. Antioxid Redox Signal, 2012. 

32.      Chen L, Lin DY and Zeng DL. Checking semiparametric transformation models with censored data. Biostatistics13(1): 18-31, 2012. 

33.      Chen L, Lin DY and Zeng DL. Predictive accuracy of covariates for event times. Biometrika 99(3): 615-630, 2012. 

34.       Dong C, Wu Y, Wang Y, Wang C, Kang T, Rychahou PG, Chi YI, Evers BM and Zhou BP. Interaction with Suv39H1 is critical for Snail-mediated E-cadherin repression in breast cancer. Oncogene, 2012. 

35.       Dong L, Kudrimoti M, Cheng R, Shang Y, Johnson EL, Stevens SD, Shelton BJ and Yu G. Noninvasive diffuse optical monitoring of head and neck tumor blood flow and oxygenation during radiation delivery. Biomed Opt Express3(2): 259-272, 2012. 

36.       Dragun AE, Huang B, Gupta S, Crew JB and Tucker TC. One decade later: trends and disparities in the application of post-mastectomy radiotherapy since the release of the American Society of Clinical Oncology clinical practice guidelines. Int J Radiat Oncol Biol Phys83(5): e591-596, 2012. 

37.       Dragun AE, Huang BTucker TC and Spanos WJ. Increasing mastectomy rates among all age groups for early stage breast cancer: a 10-year study of surgical choice. Breast J 18(4): 318-325, 2012. 

38.       Freeman AB, Huang B and Dragun AE. Patterns of care with regard to surgical choice and application of adjuvant radiation therapy for preinvasive and early stage breast cancer in rural Appalachia. Am J Clin Oncol 35(4): 358-363, 2012. 

39.       Ganguly SS, Fiore LS, Sims JT, Friend JW, Srinivasan D, Thacker MA, Cibull ML,Wang C, Novak M, Kaetzel DM and Plattner R. c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways, and drive metastatic progression. Oncogene 31(14): 1804-1816, 2012. 

40.       Gulhati P, Zaytseva YY, Valentino JD, Stevens PD, Kim JT, Sasazuki T, Shirasawa S, Lee EY, Weiss HL, Dong J, Gao T and Evers BM. Sorafenib enhances the therapeutic efficacy of rapamycin in colorectal cancers harboring oncogenic KRAS and PIK3CA. Carcinogenesis33(9): 1782-1790, 2012. 

41.       Hebbar N, Wang C and Rangnekar VM. Mechanisms of apoptosis by the tumor suppressor Par-4. J Cell Physiol227(12): 3715-3721, 2012. 

42.       Li J, Song J, Cassidy MG, Rychahou P, Starr ME, Liu J, Li X, Epperly G, Weiss HL, Townsend CM, Jr., Gao Tand Evers BM. PI3K p110alpha/Akt signaling negatively regulates secretion of the intestinal peptide neurotensin through interference of granule transport. Mol Endocrinol 26(8): 1380-1393, 2012. 

43.       Scott TL, Christian PA, Kesler MV, Donohue KM, Shelton B, Wakamatsu K, Ito S and D'Orazio J. Pigment-independent cAMP-mediated epidermal thickening protects against cutaneous UV injury by keratinocyte proliferation. Experimental Dermatology 21(10): 771-777, 2012. 

44.       Studts CR, Tarasenko YN, Schoenberg NEShelton BJ, Hatcher-Keller J and Dignan MB. A community-based randomized trial of a faith-placed intervention to reduce cervical cancer burden in Appalachia. Prev Med54(6): 408-414, 2012. 

45.       Valentino JD, Elliott VA, Zaytseva YY, Rychahou PG, Mustain WC, Wang C,Gao T and Evers BM. Novel small interfering RNA cotargeting strategy as treatment for colorectal cancer. Surgery 152(2): 277-285, 2012. 

46.      Van Meter EM, Garrett-Mayer E and Bandyopadhyay D. Dose-finding clinical trial design for ordinal toxicity grades using the continuation ratio model: an extension of the continual reassessment method. Clin Trials 9(3): 303-313, 2012. 

47.      Wang C, Parmigiani G and Dominici F. Bayesian Effect Estimation Accounting for Adjustment Uncertainty. Biometrics, 2012. 

48.       Wang X, Mandal AK, Saito H, Pulliam JF, Lee EY, Ke ZJ, Lu J, Ding S, Li L, Shelton BJ,Tucker TEvers BMZhang Zand Shi X. Arsenic and chromium in drinking water promote tumorigenesis in a mouse colitis-associated colorectal cancer model and the potential mechanism is ROS-mediated Wnt/beta-catenin signaling pathway. Toxicol Appl Pharmacol262(1): 11-21, 2012. 

49.       Wu H, Wang C and Wu Z. A new shrinkage estimator for dispersion improves differential expression detection in RNA-seq data. Biostatistics, 2012. 

50.       Wu X-C, Lund MJ, Kimmick GG, Richardson LC, Sabatino SA, Chen VW, Fleming ST, Morris CR, Huang B, Trentham-Dietz A and Lipscomb J. Influence of Race, Insurance, Socioeconomic Status, and Hospital Type on Receipt of Guideline-Concordant Adjuvant Systemic Therapy for Locoregional Breast Cancers. Journal of Clinical Oncology30(2): 142-150, 2012. 

51.       Xiong G, Wang CEvers BM,Zhou BP and Xu R. RORalpha suppresses breast tumor invasion by inducing SEMA3F expression. Cancer Res 72(7): 1728-1739, 2012. 

52.       Yu T, Chen X, Zhang W, Colon D, Shi J, Napier D, Rychahou P, Lu W, Lee EY, Weiss HL,Evers BM and Liu C. Regulation of the potential marker for intestinal cells, Bmi1, by beta-catenin and the zinc finger protein KLF4: implications for colon cancer. J Biol Chem 287(6): 3760-3768, 2012. 

53.       Zaytseva YY, Rychahou PG, Gulhati P, Elliott VA, Mustain WC, O'Connor K, Morris AJ, Sunkara M, Weiss HL, Lee EY and Evers BM. Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer. Cancer Res 72(6): 1504-1517, 2012. 

54.       Zhou Y, Wang Q, Guo Z, Weiss HL and Evers BM. Nuclear factor of activated T-cell c3 inhibition of mammalian target of rapamycin signaling through induction of regulated in development and DNA damage response 1 in human intestinal cells. Molecular Biology of the Cell 23(15): 2963-2972, 2012. 


55.         Cabanski CR, Wilkerson MD, Soloway M, Parker JS, Liu J, Prins JF, Marron JS, Perou CM and Hayes DN. BlackOPs: increasing confidence in variant detection through mappability filtering. Nucleic Acids Res 41(19):e178, 2013.

56.         Christopher KL, Wiggins AT, Van Meter EM, Means RT, Jr., Hayslip JW and Roach JP. Differences in vitamin D nutritional status between newly diagnosed cancer patients from rural or urban settings in Kentucky. Nutr Cancer65(5):653-8, 2013.

57.         Coleman SJ, Zeng Z, Hestand MS, Liu J and Macleod JN. Analysis of unannotated equine transcripts identified by mRNA sequencing. PLoS One 8(7):e70125, 2013.

58.         Dong C, Wu Y, Wang Y, Wang C, Kang T, Rychahou PG, Chi YI, Evers BM and Zhou BP. Interaction with Suv39H1 is critical for Snail-mediated E-cadherin repression in breast cancer. Oncogene 32(11):1351-62, 2013.

59.         Engstrom PG, Steijger T, Sipos B, Grant GR, Kahles A, Ratsch G, Goldman N, Hubbard TJ, Harrow J, Guigo R, Bertone P and Consortium R. Systematic evaluation of spliced alignment programs for RNA-seq data. Nat Methods10(12):1185-91, 2013.

60.         Feddock J, Cleary R, Arnold SM, Shelton B, Sinha P, Conrad G, Chen L, Rinehart J and Mcgarry R. Risk for Fatal Pulmonary Hemorrhage does not appear to be increased following dose escalation using Stereotactic Body Radiotherapy (SBRT) in Locally Advanced Non-Small Cell Lung Cancer (NSCLC). Journal of Radiosurgery & SBRT 2(3):325, 2013.

61.         Hollis CP, Weiss HL, Leggas M, Evers BM, Gemeinhart RA and Li T. Biodistribution and bioimaging studies of hybrid paclitaxel nanocrystals: lessons learned of the EPR effect and image-guided drug delivery. J Control Release172(1):12-21, 2013.

62.         Huang Y, Hu Y, Jones CD, MacLeod JN, Chiang DY, Liu Y, Prins JF and Liu J. A robust method for transcript quantification with RNA-seq data. J Comput Biol 20(3):167-87, 2013.

62.         Jeck WR, Sorrentino JA, Wang K, Slevin MK, Burd CE, Liu J, Marzluff WF and Sharpless NE. Circular RNAs are abundant, conserved, and associated with ALU repeats. RNA 19(2):141-57, 2013.

64.       Kim JT, Li J, Jang ER, Gulhati P, Rychahou PG, Napier DL, Wang CWeiss HL, Lee EY, Anthony L, Townsend CM, Jr., Liu C and Evers BM. Deregulation of Wnt/beta-catenin signaling through genetic or epigenetic alterations in human neuroendocrine tumors. Carcinogenesis 34(5):953-61, 2013.

65.       McGarry RC, Feddock J, Sinha P, Conrad G, Shelton BJ,Chen L, Arnold SM and Rinehart J. Early PET/CT for Assessing Treatment Responses of non-small cell lung cancer for SBRT Boost: what to do with scans from multiple scanners. Journal of Radiosurgery and SBRT 2(4):315-23, 2013.

66.       Mustain WC, Starr ME, Valentino JD, Cohen DA, Okamura D, Wang C, Evers BM and Saito H. Inflammatory cytokine gene expression in mesenteric adipose tissue during acute experimental colitis. PLoS One 8(12):e83693, 2013.

67.       Narayanasamy G, Smith A, Van Meter E, McGarry R and Molloy JA. Total target volume is a better predictor of whole brain dose from gamma stereotactic radiosurgery than the number, shape, or location of the lesions. Med Phys40(9):091714, 2013.

68.       Rinehart J, Arnold S, Kloecker G, Lim A, Zaydan MA, Baeker T, Maheshwari JG, Carloss H, Slone SShelton B, Croley J, Kvale E, Brooks M and Leggas M. Phase II randomized trial of carboplatin and gemcitabine with or without dexamethasone pre-treatment in patients with Stage IV non-small cell lung cancer. Cancer Chemother Pharmacol71(5):1375-83, 2013.

69.       Shang Y, Lin Y, Henry BA, Cheng R, Huang C, Chen L,Shelton BJ, Swartz KR, Salles SS and Yu G. Noninvasive evaluation of electrical stimulation impacts on muscle hemodynamics via integrating diffuse optical spectroscopies with muscle stimulator. J Biomed Opt 18(10):105002, 2013.

70.       Slone S, White C, Shelton BVan Meter E, DeSimone C, Schoenberg N and Dignan M. Inconsistencies between medical records and patient-reported recommendations for follow-up after abnormal Pap tests. J Womens Health (Larchmt) 22(2):147-52, 2013.

71.       Sui X, Li H, Zhang J, Chen L, Zhu L and Blair SN. Percentage of deaths attributable to poor cardiovascular health lifestyle factors: Findings from the Aerobics Center Longitudinal Study. Epidemiol Res Int pii:437465, 2013. 

72.       Vanderford NL,Weiss LT and Weiss HL. A survey of the barriers associated with academic-based cancer research commercialization. PLoS One 8(8):e72268, 2013.

73.       Wang Q, Zhou Y, Rychahou P, Liu C, Weiss HL and Evers BM. NFAT5 represses canonical Wnt signaling via inhibition of beta-catenin acetylation and participates in regulating intestinal cell differentiation. Cell Death Dis 4:e671. doi: 10.1038/cddis.2013.202, 2013.

74.       Wu H, Wang C and Wu Z. A new shrinkage estimator for dispersion improves differential expression detection in RNA-seq data. Biostatistics 14(2):232-43, 2013.

75.       Wu Y, Wang Y, Yang XH, Kang T, Zhao Y, Wang C, Evers BM and Zhou BP. The deubiquitinase USP28 stabilizes LSD1 and confers stem-cell-like traits to breast cancer cells. Cell Rep 5(1):224-36, 2013.


76.       Alqaisi A, Chen L, Romond E, Chambers M, Stevens M, Pasley G, Awasthi M and Massarweh S. Impact of estrogen receptor (ER) and human epidermal growth factor receptor-2 (HER2) co-expression on breast cancer disease characteristics: implications for tumor biology and research. Breast Cancer Res Treat148(2):437-44, 2014.

77.       Cancer Genome Atlas Research N. Comprehensive molecular profiling of lung adenocarcinoma. Nature511(7511):543-50, 2014.

78.       Cancer Genome Atlas Research N. Integrated genomic characterization of papillary thyroid carcinoma. Cell159(3):676-90, 2014.  

79.       Chen L, Voronovich Z, Clark K, Hands I, Mannas J, Walsh M, Nikiforova MN, Durbin EB, Weiss H and Horbinski C. Predicting the likelihood of an isocitrate dehydrogenase 1 or 2 mutation in diagnoses of infiltrative glioma. Neuro Oncol 16(11):1478-83, 2014.

80.       Dignan M, Shelton BSlone SA, Tolle C, Mohammad S, Schoenberg N, Pearce K, Van Meter E and Ely G. Effectiveness of a primary care practice intervention for increasing colorectal cancer screening in Appalachian Kentucky. Prev Med 58(70-4, 2014.

81.       Dignan MB, White C, Schoenberg N, Shelton B, Feltner F, Slone SVan Meter E, DeSimone C and Ely G. Effectiveness of a Patient Navigation Intervention to Increase Adherence to Follow-Up Recommendations for Women with Abnormal Pap Tests in Appalachian Kentucky. Journal of Health Behavior & Policy Review 1(1):6-15, 2014.

82.       Ely GE, White C, Jones K, Feltner F, Gomez M, Shelton B, Slone S, Van Meter E, Desimone C, Schoenberg N and Dignan M. Cervical cancer screening: exploring Appalachian patients' barriers to follow-up care. Soc Work Health Care53(2):83-95, 2014.

83.       Etter NM, Van Meter EM and Andreatta RD. Orofacial Somatosensory Perceptual Changes in Healthy Aging Versus Young Adult Participants. Perceptual & Motor Skills118(2):622-35, 2014.

84.       Feddock J, Randall M, Kudrimoti M, Baldwin L, Shah P, Weiss H and Desimone C. Impact of post-radiation biopsies on development of fistulae in patients with cervical cancer. Gynecol Oncol 133(2):263-7, 2014.

85.       Fiore LS, Ganguly SS, Sledziona J, Cibull ML, Wang C, Richards DL, Neltner JM, Beach C, McCorkle JR, Kaetzel DM and Plattner R. c-Abl and Arg induce cathepsin-mediated lysosomal degradation of the NM23-H1 metastasis suppressor in invasive cancer. Oncogene 33(36):4508-20, 2014.

86.       Guo L, Zheng Z, Ai J, Huang B and Li XA. Hepatic scavenger receptor BI protects against polymicrobial-induced sepsis through promoting LPS clearance in mice. J Biol Chem 289(21):14666-73, 2014.

87.       Hollis CP, Weiss HL, Evers BM, Gemeinhart RA and Li T. In vivo investigation of hybrid Paclitaxel nanocrystals with dual fluorescent probes for cancer theranostics. Pharm Res 31(6):1450-9, 2014.

88.       Huang B, Guo J and Charnigo R. Statistical Methods for Population-Based Cancer Survival in Registry Data J Biomet Biostat 5: e129. doi: 10.4172/2155-6180.1000e129 2014.

89.       Huang Y, Hu Y and Liu J. Piecing the puzzle together: a revisit to transcript reconstruction problem in RNA-seq. BMC Bioinformatics 15(Suppl 9):S3, 2014.

90.       Kasakoff AB, Lawson AB and Van Meter EM. A Bayesian analysis of the spatial concentration of individual wealth in the US North during the nineteenth century. Demographic Research 30(36):1035-74, 2014.

91.       Li X, Stevens PD, Liu J, Yang H, Wang W, Wang C, Zeng Z, Schmidt MD, Yang M, Lee EY and Gao T. PHLPP is a Negative Regulator of RAF1 that Reduces Colorectal Cancer Cell Motility and Prevents Tumor Progression in Mice. Gastroenterology146(5):1301-12, 2014.

92.       Long KL, Huang B, Guo J, Lee C, Sloan D and McKenzie S. Concerning trends in Appalachian patients with thyroid carcinoma. Am Surg 80(6):620-3, 2014.

93.       Massarweh S, Moss J, Wang C, Romond E, Slone S, Weiss H, Karabakhtsian RG, Napier D and Black EP. Impact of adding the multikinase inhibitor sorafenib to endocrine therapy in metastatic estrogen receptor-positive breast cancer. Future Oncol 10(15):2435-48, 2014.

94.       Massarweh S, Romond E, Black EP, Van Meter E, Shelton B, Kadamyan-Melkumian V, Stevens M and Elledge R. A phase II study of combined fulvestrant and everolimus in patients with metastatic estrogen receptor (ER)-positive breast cancer after aromatase inhibitor (AI) failure. Breast Cancer Res Treat143(2):325-32, 2014.

95.       Parfenov M, Pedamallu CS, Gehlenborg N, Freeman SS, Danilova L, Bristow CA, Lee S, Hadjipanayis AG, Ivanova EV, Wilkerson MD, Protopopov A, Yang L, Seth S, Song X, Tang J, Ren X, Zhang J, Pantazi A, Santoso N, Xu AW, Mahadeshwar H, Wheeler DA, Haddad RI, Jung J, Ojesina AI, Issaeva N, Yarbrough WG, Hayes DN, Grandis JR, El-Naggar AK, Meyerson M, Park PJ, Chin L, Seidman JG, Hammerman PS, Kucherlapati R and Cancer Genome Atlas N. Characterization of HPV and host genome interactions in primary head and neck cancers. Proc Natl Acad Sci U S A111(43):15544-9, 2014.

96.       Qi Y, Zhang M, Li H, Frank JA, Dai L, Liu H, Wang C, Zhang Z and Chen G. Inhibition of autophagy by sustained over-production of IL-6 contributes to arsenic carcinogenesis. Cancer Research. Cancer Research 74(14):3740-52, 2014.

97.       Shi J, Wang Y, Zeng L, Wu Y, Deng J, Zhang Q, Lin Y, Li J, Kang T, Tao M, Rusinova E, Zhang G, Wang C, Zhu H, Yao J, Zeng YX, Evers BM, Zhou MM and Zhou BP. Disrupting the interaction of BRD4 with diacetylated Twist suppresses tumorigenesis in basal-like breast cancer. Cancer Cell 25(2):210-25, 2014.

98.       Tian S, Chang HH, Wang C, Jiang J, Wang X and Niu J. Multi-TGDR, a multi-class regularization method, identifies the metabolic profiles of hepatocellular carcinoma and cirrhosis infected with hepatitis B or hepatitis C virus. BMC Bioinformatics 15:97, doi:10.1186/1471-2105-15-97, 2014.

99.       Valentino JD, Li J, Zaytseva YY, Mustain WC, Elliott VA, Kim JT, Harris JW, Campbell K, Weiss H, Wang C, Song J, Anthony L, Townsend CM, Jr. and Evers BM. Cotargeting the PI3K and RAS pathways for the treatment of neuroendocrine tumors. Clin Cancer Res 20(5):1212-22, 2014.

100.       Van Meter EM and Charnigo R. Strengthening Interactions between Statisticians and Collaborators: Objectives and Sample Sizes. J Biomet Biostat 5: e127. doi: 10.4172/2155-6180.1000e127, 2014. 

101.       Xu X, Yu T, Shi J, Chen X, Zhang W, Lin T, Liu Z, Wang Y, Zeng Z, Wang C, Li M and Liu C. Thymine DNA glycosylase is a positive regulator of Wnt signaling in colorectal cancer. J Biol Chem 289(13):8881-90, 2014.

102.       Zaytseva YY, Elliott VA, Rychahou P, Mustain WC, Kim JT, Valentino J, Gao T, O'Connor KL, Neltner JM, Lee EY, Weiss HL and Evers BM. Cancer cell-associated fatty acid synthase activates endothelial cells and promotes angiogenesis in colorectal cancer. Carcinogenesis 35(6):1341-51, 2014.

103.       Zhang A, Wang C, Wang SJ, Li L, Liu ZM and Tian SY. Visualization-Aided Classification Ensembles Discriminate Lung Adenocarcinoma and Squamous Cell Carcinoma Samples Using Their Gene Expression Profiles. Plos One9(10):2014.

104.       Zhong Y, Morris DH, Jin L, Patel MS, Karunakaran SK, Fu YJ, Matuszak EA, Weiss HL, Chait BT and Wang QJ. Nrbf2 protein suppresses autophagy by modulating Atg14L protein-containing Beclin 1-Vps34 complex architecture and reducing intracellular phosphatidylinositol-3 phosphate levels. J Biol Chem289(38):26021-37, 2014.

105.       Zhou Y, Wang Q, Weiss HL and Evers BM. Nuclear factor of activated T-cells 5 increases intestinal goblet cell differentiation through an mTOR/Notch signaling pathway.Mol Biol Cell 25(18):2882-90, 2014.    

Accepted / In Press

106. Chen A, Chen L, Al-Qaisi A, Romond E, Awasthi M, Kadamyan-Melkumyan V and Massarweh S. Everolimus-Induced Hematologic Changes in Patients With Metastatic Breast Cancer. Clin Breast Cancer 15(1):48-532014, 2015.

107.       Wu H, Wang C and Wu Z. PROPER: comprehensive power evaluation for differential expression using RNA-seq. Bioinformatics 31(2):233-41, 2015.

108.       Lian H, Lin Y, Shang Y, Shelton BJ and Yu G. Using Optical Fibers with Different Modes to Improve the Signal-to-Noise Ratio of DCS Flow-Oximeter Measurement. Journal of Biomedical Opticsaccepted.

109.       Zhang Y, Wang Q, Chen L and Yang HS. Inhibition of p70S6K1 activation by Pdcd4 overcomes the resistance to IGF-1R/IR inhibitor in colon carcinoma cells. Molecular Cancer Therapeutics accepted.

110.       Al-Kadhimi Z, Gul Z, Van Meter E, Abidi MH, Ditah I, Abdul-Hussein M, Deol A, Ayash LJ, Lum L, Waller E, Ratanatharathron V and Uberti J. Low Blood Lymphocyte Count at 30 Days Post Transplant Predicts Worse Acute Graft versus Host Disease and Survival but not Relapse in a Large Retrospective Cohort. Bone Marrow Transplantationin press.

111.       Allemani C, Weir HK, Carreira H, Harewood R, Spika D, Wang XS, Bannon F, Ahn JV, Johnson CJ, Bonaventure A, Macros-Gragera R, Stiller C, Azevedo e Silva G, Chen WQ, Ogunbiyi OJ, Rachet B, Soeberg MJ, You H, Matsuda T, Bielska, Lasota M, Storm H, Tucker TC, Coleman MP and Group CW. Global surveillance of cancer survival 1995-2009: analysis of individual data for 25,676,877 patients from 279 population-based registries in 67 countries (CONCORD-2). Lancet in press.

112.       Baldwin L, Hoff J, Lefringhouse J, Zhang M, Jia C, Lui Z, Erfani S, Jin H, Xu M, She Q, van Nagell J, Wang C, Chen L, Plattner R, Kaetzel D, Luo J, Lu M, West D, Liu C, Ueland F, Drapkin R, Zhou B and Yang X. CD151-α3β1 integrin complexes suppress ovarian tumor growth by repressing slug-mediated EMT and canonical Wnt signaling. Oncogenein press.

113.       Moss J, Black P, Wang C, Li L, Sloan S, Lye A, Romond E, Weiss H and Massarweh S. The multikinase inhibitor sorafenib can overcome antiestrogen resistance in patients with progressive metastatic estrogen receptor (ER) positive breast cancer. Future Oncology in press.

114.       Shoenberg N, Huang B, Seshadri S and Tucker TC. Trends in the leading preventable contributors to chronic disease--smoking and obesity- in Appalachian Kentucky. Southern Medical Journal in press.

115.       St. Clair D, Xu Y, Miriyala S, Fang F, Bakthavatchalu V, Noel T, Wang C and St. Clair W. Manganese superoxide dismutase deficiency triggers mitochondrial uncoupling and the warburg effect. Oncogene in press.

116.       Vanderpool RC, Van Meter E and Stradtman LR. Fatalistic Beliefs and Completion of the Human Papillomavirus (HPV) Vaccination Series among a Sample of Young Appalachian Kentucky Women. Journal of Rural Health in press.

117.       Wang C, Tan Z and Louis TA. An Exponential Tilt Mixture Model for Time-to-Event Data to Evaluate Treatment Effect Heterogeneity in Randomized Clinical Trials.  Biometrics & Biostatistics International Journal in press.

118.       Wang C, Tan Z and Louis TA. An Exponential Tilt Model for Quantitative Trait Loci Mapping with Time-to-Event Data.  Journal of Bioinformativs Research Studiesin press.