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CV genetics: Tailored management of hereditary heart issues

Dr. Apostolos Psychogios
Dr. Apostolos "Paul" Psychogios

Led by our genetics expert, Apostolos "Paul" Psychogios, MD, the Cardiovascular Genetics and Precision Medicine Program at the UK Gill Heart & Vascular Institute specializes in the diagnosis and treatment of hereditary cardiovascular diseases, and in researching new approaches to preventing and treating those diseases.

Precision medicine is the new frontier of healthcare, and this highly specialized program is proud to be the first of its kind to address heart and vascular disorders in Kentucky.

The charge of the program is threefold: We provide clinical genetic service to inpatients and outpatients, facilitate and engage in clinical genetics and genomics research, and promote the genetic and genomic education of faculty, staff and students.

Our clinicians and researchers work to understand the role genetics play in cardiovascular disease on both the individual and the societal level.

We offer a full array of genetic testing, including:

  • Single gene analysis (sequencing and deletion/duplication analysis).
  • Next generation sequencing (NGS) multigene panels.
  • Whole exome sequencing (WES).
  • Whole genome sequencing (WGS).
  • SNP-microarrays.
  • Metabolic testing.
  • Pharmacogenomics testing.

In clinical service, the team provides evaluation and management recommendations based on the genomic status of patients with familial and unknown etiology heart disorders such as cardiomyopathy, heart failure, arrhythmias and channelopathies, connective tissue disorders and coronary artery disease.

See more stories from 2018 State of the Heart