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John L. Villano, MD, PhD

Director, Clinical Neuro-Oncology Research Program
| 4.79 out of 5
19 ratings | 5 comments
  • About

    John L. Villano specializes in the treatment of brain cancers. He will advance UK HealthCare's Clinical Neuro-Oncology Research Program, serving as its director. UK HealthCare has a history of being a world-class neuro-oncology program, and he will help carry this tradition into the future.

    Previously, Dr. Villano served as the director of medical neuro-oncology at the University of Illinois Medical Center. He earned a medical degree and doctor of philosophy at the University of Texas Southwestern Medical School at Dallas and trained in neurology at the University of Michigan. He also completed a fellowship in hematology/oncology at the University of Chicago. He is a former American Society of Clinical Oncology track leader for CNS tumors. Currently, he is on the board of the Central Brain Tumor Registry US. He is also a member of the Neuro-Oncology Committee in the cooperative group ALLIANCE and a Society of Neuro-Oncology committee member.

    Faculty Rank

    Medical Director, Precision Medicine Clinic
    Professor of Medicine


    University of Texas Southwestern Medical Center, Dallas


    Neurology, University of Michigan Medical School, Ann Arbor

    Internal Medicine, Cook County Hospital, Chicago


    Hematology/Oncology, University of Chicago

    Certifications and Special Training

    American Board of Internal Medicine

    American Board of Internal Medicine, Medical Oncology

  • Publications


    1. Four-jointed is required for intermediate growth in the proximal-distal axis in Drosophila. Villano, J.L. and Katz, F.N. (1995) Development. 121:2767-77.
    2. NovoTTF-100A versus physician's choice chemotherapy in recurrent glioblastoma: A randomised phase III trial of a novel treatment modality. Stupp, R., Wong, E.T., Kanner, A.A., Steinberg, D., Engelhard, H., Heidecke, V., Kirson, E.D., Taillibert, S., Liebermann, F., Dbalý, V., Ram, Z., Villano, J.L., Rainov, N., Weinberg, U., Schiff, D., Kunschner, L., Raizer, J., Honnorat, J., Sloan, A., Malkin, M., Landolfi, J.C., Payer, F., Mehdorn, M., Weil, R.J., Pannullo, S.C., Westphal, M., Smrcka, M., Chin, L., Kostron, H., Hofer, S., Bruce, J., Cosgrove, R., Paleologous, N., Palti, J., Gutin, P.H. (2012) Eur J Cancer. 48(14):2192-202
    3. Incidence of Brain Metastasis at Initial Presentation of Lung Cancer. Villano, J.L., Durbin, E.B., Normandeau, C., Thakkar, J.P., Moirangthem, V., Davis, F.G. (2014) Neuro-Oncol. 17(1):122-8
    4. Epidemiology of Meningiomas Post Public Law 107-206 - The Benign Brain Tumor Cancer Registries Amendment Act. Dolecek, T.A., Dressler, E.V., Thakkar, J.P., Liu, M., Al-Qaisi, A., Villano, J.L. (2015) Cancer. 121(14):2400-10
    5. Incidence of CNS tumors in Appalachian children. Huang, B., Luo, A., Durbin, E.B., Lycan, E., Tucker, T., Chen, Q., Horbinski, C., Villano, J.L. (2017) J Neuro-Oncol. Mar 11. [Epub ahead of print].
  • Research

    Cancer Center Member

    Research Focus

    Clinical Trials involved in Neuro-Oncology and in lung cancer. I am also involved in collaborated with the investigators at Kentucky Cancer Registry (KCR) and at Central Brain Tumor Registry of the United States (CBTRUS) to perform descriptive epidemiology studies. We have worked on topics that are less known or investigated, where application of clinical knowledge assists in interpretation of epidemiology data. 

    For Referring Physicians

    800 Rose St.
    CC 446
    Lexington, KY 40536
    United States

  • Ratings & Reviews

    - Overall Provider Rating: 4.79 out of 5 · 19 ratings · 5 comments

    The star rating is a calculation based on feedback from our patients using our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more about our survey process. Responses are measured on a scale of 1 to 5 with 5 being the best score.

    May, 2019
    Very fast and courteous.

    October, 2018
    really, really great

    September, 2018
    We (family) think highly of *Dr John Villano AND *Markey!

    August, 2018
    Great experience!!

    August, 2018
    Very professional & at ease.