Biology Research Programs
Molecular genetic analysis (c-Ki-ras-2; HER-2/neu; p53;
microstaellite instability and TGF-b receptor II mutation) of
pancreatic adenocarcinoma: detection of circulating tumor cells in
peripheral blood and the spectrum of gene alterations in primary
tumor will provide leads for future radiation and chemotherapy
P53 and HER-2/neu gene analysis in primary tumor of breast
adenocarcinoma patients undergoing bone marrow transplantation will
detect occult tumor cells in peripheral blood stem cell pharisees
samples to prevent transfusion of tumor cells.
Head and neck tumors
Analysis of gene alterations in primary tumor, surgical margins
and normal tissue using fluorescent in-situhybridization (FISH) and
polymerase chain reaction.
Regulatory and functional role of EGR-1: in-vitro and in-vivo role
of basal and radiation-induced EGR-1 expression levels are being
assessed to understand tumor resistance to radiation.
Molecular basis of grid
Growth inhibition, apoptosis and gene expression analysis in cell
lines exposed to radiation with grid therapy to understand the role
Cervix and ovarian cancer (Korean
H-ras point mutation and expression analysis in primary tumor of
cervical and ovarian cancer versus clinicopathological