• For medical professionals

    gillprof

    The UK Gill Heart Institute’s comprehensive approach to heart and vascular health begins with promoting cardiovascular wellness and extends to treating life-threatening complications with the newest therapies and devices. Our greatest asset is our faculty, a multidisciplinary clinical team that includes members from six services:

    • Adult cardiology
    • Pediatric cardiology
    • Cardiothoracic surgery
    • Vascular surgery
    • Cardiac radiology
    • Cardiac anesthesiology



  • About Gill

    Our leading-edge facilities are available in the UK Albert B. Chandler Hospital, UK Good Samaritan Hospital, office locations at the Gill Heart Institute building on the UK campus, at Maxwell Street in downtown Lexington and at nearly a dozen outreach sites around the Commonwealth.

    The Gill Heart Institute serves as a local referral center for the treatment of cardiovascular diseases. We offer the only advanced heart failure and transplantation program in the region, and we are one of 34 centers in the United States certified in the implantation of the SynCardia temporary Total Artificial Heart. The Gill Imaging Center, equipped with two 64-slice CT scanners, a 1.5 Tesla and a 3.0 Tesla MRI scanner, performs complex adult and pediatric cases in close collaboration between cardiology and radiology.

    Our complete cardiovascular care includes a cardiac rehabilitation program, leading-edge electrophysiology and interventional cardiology procedures, minimally-invasive approaches to structural heart disease and extensive surgical services for heart and vascular disease.  

    Our aim is to provide every patient with exceptionally compassionate care in the safest and most appropriate manner possible based on the best evidence and latest technological advances. 

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  • Clinical trials

    CURRENT ENROLLING CLINICAL TRIALS

    ALLSTAR (Capricor)
    DREAM HF (TEVA)
    Sildenafil HF (GHI)
    SURTAVI (Medtronic)
    CADENCE (Otsuka)
    ISCHEMIA (NHLBI/NYUSOM)
    CIRT (NHLBI/Brigam and Women’s)
    VEST/VEST REGISTRY (U of CA-SF)
    (VA) DIVA
    ENHANCE CRT (SJM)
    ABSORB IV (Abbott)
    TCAP (Vanderbilt and Astra Zeneca)
    Upcoming trials

    ALLSTAR (Capricor)

    Allogeneic Heart Stem Cells to Achieve Myocardial Regeneration in patients with ischemic heart failure

    PI: Ahmed Abdel-Latif, MD, PhD

    • Treatment and/or prevention of left ventricular dysfunction following myocardial infarction

    For more information about this study, contact:

    Yvonne Taul, RN
    859-2181644
    Email: yvonne.taul@uky.edu

    Return to list »


    DREAM HF (TEVA)

    Efficacy and Safety Study of Allogeneic stem cells in Patients with Chronic Heart Failure Due to Left Ventricular Systolic Dysfunction of Either Ischemic or Nonischemic Etiology

    PI: Ahmed Abdel-Latif, MD, PhD

    • Restoring the function of damaged heart muscle with experimental study product cells

    For more information about this study, contact:

    Heather Shinall
    859-323-5259
    Email: h.shinall@uky.edu

    Return to list »


    Sildenafil HF (GHI)

    Sildenafil in Heart Failure with Reactive Pulmonary Hypertension

    PI: Maya Guglin, MD, PhD

    • To determine whether sildenafil can improve exercise tolerance measured by 6 minute walk distance
    • To determine whether sildenafil can improve hemodynamics, right ventricular function, or quality of life

    For more information about this study, contact:

    Heather Shinall
    859-323-5259
    Email: h.shinall@uky.edu

    Return to list »


    SURTAVI (Medtronic)

    Surgical Replacement and Transcatheter Aortic Valve Implantation. The purpose of this trial is to investigate the safety and efficacy of transcatheter aortic valve implantation (TAVI) in patients with severe, symptomatic Aortic Stenosis (AS) at intermediate surgical risk by randomizing patients to either Surgical Aortic Valve Replacement (SAVR) or TAVI.

    PIs: John Gurley, MD & Mike Sekela, MD

    For more information about this study, contact:

    Kelli Frueh, RN
    859-323-8516
    Email: kelli.frueh@uky.edu

    Return to list »


    CADENCE (Otsuka)

    Ascending Dose Study of OPC-108459 Intravenous Infusions in Patients with Paroxysmal and Persistent Atrial Fibrillation

    PI: Samy-Claude Elayi, MD

    • Ages 18-85
    • Paroxysmal and persistent atrial fibrillation
    • Must determine eligibility prior to cardioversion

    For more information about this study, contact:

    Rebekah Evans, RN
    859-323-8663
    Email: rastan2@uky.edu

    Return to list »


    ISCHEMIA (NHLBI/NYUSOM)

    International Study of Comparative Health Effectiveness with Medical and Invasive Approaches invasive strategy ( initial management with cath) vs. conservative strategy (initial management with optimal medical therapy [OMT] and provisional cath if OMT fails) in ischemic patients

    PI: David Booth, MD

    • Patients with at least moderate ischemia on a stress imaging test

    For more information about this study, contact:

    Yvonne Taul, RN
    859-218-1644
    Email: Yvonne.taul@uky.edu

    Return to list »


    CIRT (NHLBI/Brigham and Women’s)

    Cardiovascular Inflammation Reduction Trial

    PI: Alison Bailey, MD

    • Investigating whether taking low-dose methotrexate reduces heart attacks, strokes, or death in people with type 2 diabetes or metabolic syndrome that have had a heart attack

    For more information about this study, contact:

    Kelli Frueh, RN
    859-323-8516
    Email: kelli.frueh@uky.edu

    Return to list »


    VEST/VEST Registry (U of CA-SF)

    Non-invasive wearable automatic defibrillator vest will reduce mortality in first 90 days post MI in pts w/ LV dysfunction (≤35%)

    PI: Samy-Claude Elayi, MD

    • STEMI / NSTEMI with EF ≤ 35%
    • LifeVest vs. medical management for 3 months
    • Registry is continuation of data collection for up to 8 years annually

    For more information about this study, contact:

    Yvonne Taul, RN
    859-218-1644
    Email: yvonne.taul@uky.edu

    Return to list »


    (VA) DIVA

    Drug-Eluting Stents vs. Bare Metal Stents in Saphenous Vein Graft Angioplasty

    PI: Khaled Ziada, MD

    • Patients with hx of CABG who are scheduled for PCI to SVG

    For more information about this study, contact:
    Yvonne Taul, RN
    859-218-1644
    Email: yvonne.taul@uky.edu

    Return to list »


    Enhance CRT (SJM)

    CRT Implant Strategy using the longest electrical delay for non-LBB patients; randomized, post-market pilot study

    PI: Gustavo Morales, MD

    • Patients with non-left bundle branch block, eligible for bi-ventricular ICD implant

    For more information about this study, contact:

    Rebekah Evans, RN
    859-323-8663
    Email: rastan2@uky.edu

    Return to list »


    ABSORB IV (Abbott)

    A Clinical Evaluation of Absorb™ BVS, the Everolimus Eluting Bioresorbable Vascular Scaffold in the Treatment of Subjects with de Novo Native Coronary Artery Lesions.

    PI: Khaled Ziada, MD

    • Patients with indication for elective LHC and possible PCI

    For more information about this study, contact:

    Caroline Rodgers, RN
    859-323-1082
    Email: caroline.rodgers@uky.edu

    Return to list »


    TCAP (Vanderbilt and Astra Zeneca)

    Randomized Trial of Ticagrelor for Severe Community Acquired Pneumonia

    PI: Susan Smyth, MD, PhD

    • Patients with Severe Community Acquired Pneumonia, within 48 hours of admission

    For more information about this study, contact:

    Travis Sexton, PhD
    859-323-3617
    Email: trsex2@uky.edu

    Return to list »


    Upcoming:

    Aegis-1 (CLS) – Phase 2b, Multi-center, Randomized, Placebo-controlled, Dose-ranging Study to Investigate the Safety and Tolerability of Multiple Dose Administration of CSL112 in Subjects with Acute Myocardial Infarction

    PI: Alison Bailey, MD

    COMMANDER HF (Janssen) – A Randomized, Double-blind, Event-driven, Multicenter Study Comparing the Efficacy and Safety of Rivaroxaban with Placebo for Reducing the Risk of Death, Myocardial Infarction or Stroke in Subjects with Heart Failure and Significant Coronary Artery Disease Following an Episode of Decompensated Heart Failure

    PI: Navin Rajagopalan, MD

    RE-DUAL PCI (Boehringer Ingelheim) – A prospective Randomised, open label, blinded endpoint (PROBE) study to Evaluate DUAL antithrombotic therapy with dabigatran etexilate plus clopidogrel or ticagrelor vs. triple therapy strategy with warfarin plus clopidogrel or ticagrelor and aspirin in patients with non valvular atrial fibrillation (NVAF) that have undergone a percutaneous coronary intervention (PCI) with stenting

    PI: Adrian Messerli, MD

    EMANATE (Pfizer) – A Phase IV Trial to Assess the Effectiveness of Apixaban Compared with Usual Care Anticoagulation in Subjects with Non-Valvular Atrial Fibrillation Undergoing Cardioversion

    PI: Adrian Messerli, MD

    Return to list »

  • Referrals

    The Gill Heart Institute serves as a local referral center for the treatment of cardiovascular diseases. To refer a patient for any of our areas of service expertise, call UK•MDs at 800-888-5533..

  • Gill-outreach-map 

    Gill Heart Institute Outreach sites (PDF, 190 KB) »

    Cardiology

    ARH Regional Medical Center | Directions »
    Hazard, KY 
    Call 859-323-0295 or toll-free 1-877-700-5479 for appointments

    Clark Regional Medical Center | Directions »
    Winchester, KY 
    Call 859-323-0295 or toll-free 1-877-700-5479 for appointments

    Georgetown Community Hospital | Directions »
    Georgetown, KY 
    Call 859-323-0295 or toll-free 1-877-700-5479 for appointments

    Norton Audubon Hospital | Directions »
    (Heart failure, Cardiac transplant and Mechanical support)
    Louisville, KY
    Call 859-323-0295 or toll-free 1-877-700-5479 for appointments

    Rockcastle Hospital | Directions »
    Mt Vernon, KY 
    Call 859-323-0295 or toll-free 1-877-700-5479 for appointments

    St. Claire Regional Medical Center | Directions »
    (electrophysiology only)
    Morehead, KY 
    Call 859-323-0295 or toll-free 1-877-700-5479 for appointments

    Cardiothoracic Surgery

    For appointments in the following regions, call 859-323-6494: 

    • Boyle County
    • Harrison County
    • Perry County
    • Rockcastle County

    Vascular Surgery

    For appointments in the following regions, call 859-257-3253:

    • Danville 
    • Hazard
    • Prestonsburg