• For medical professionals

    gillprof

    The UK Gill Heart Institute’s comprehensive approach to heart and vascular health begins with promoting cardiovascular wellness and extends to treating life-threatening complications with the newest therapies and devices. Our greatest asset is our faculty, a multidisciplinary clinical team that includes members from six services:

    • Adult cardiology
    • Pediatric cardiology
    • Cardiothoracic surgery
    • Vascular surgery
    • Cardiac radiology
    • Cardiac anesthesiology



  • About Gill

    Our leading-edge facilities are available in the UK Albert B. Chandler Hospital, UK Good Samaritan Hospital, office locations at the Gill Heart Institute building on the UK campus, at Maxwell Street in downtown Lexington and at nearly a dozen outreach sites around the Commonwealth.

    The Gill Heart Institute serves as a local referral center for the treatment of cardiovascular diseases. We offer the only advanced heart failure and transplantation program in the region, and we are one of 34 centers in the United States certified in the implantation of the SynCardia temporary Total Artificial Heart. The Gill Imaging Center, equipped with two 64-slice CT scanners, a 1.5 Tesla and a 3.0 Tesla MRI scanner, performs complex adult and pediatric cases in close collaboration between cardiology and radiology.

    Our complete cardiovascular care includes a cardiac rehabilitation program, leading-edge electrophysiology and interventional cardiology procedures, minimally-invasive approaches to structural heart disease and extensive surgical services for heart and vascular disease.  

    Our aim is to provide every patient with exceptionally compassionate care in the safest and most appropriate manner possible based on the best evidence and latest technological advances. 

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  • Clinical trials

    CURRENT ENROLLING CLINICAL TRIALS

    COMPASSION S3 (Edwards Lifesciences)
    CardioMEMS HF System PAS (Post Approval Study) (St. Jude Medical)
    FAME 3 (Stanford University)
    TWILIGHT (Mt. Sinai Medical School)
    VOYAGER PAD (Bayer Pharmaceuticals)
    MOMENTUM 3 CAP (St. Jude Medical)
    AEGIS 2001 (CSL Berhing)
    DREAM HF (TEVA)
    Sildenafil HF (GHI)
    ISCHEMIA (NHLBI/NYUSOM)
    CIRT (NHLBI/Brigam and Women’s)
    VEST/VEST REGISTRY (U of CA-SF)
    ENHANCE CRT (SJM)
    ABSORB IV (Abbott)
    Spyral HTN ON Meds (Medtronic)
    Spyral HTN OFF Meds (Medtronic)

    COMPASSION S3 (Edwards Lifesciences)

    Congenital Multicenter trial of Pulmonic vAlve dysfunction Studying the SAPIEN 3 interventIONal THV

    PI: Andrew Leventhal, MD, PhD

    • To determine safety and efficacy of the Edwards Sapien 3 Transcatheter Heart Valve System in patients with dysfunctional right ventricular outflow tract with clinical indication for intervention

    For more information about this study, contact:

    Jennifer Isaacs
    859-323-4738
    Email: Jennifer.isaacs@uky.edu

    Return to list »


    CardioMEMS HF System PAS (Post Approval Study) (St. Jude Medical)

    PI: Maya Guglin, MD, PhD

    • Continued collection of safety and efficacy data following FDA approval of device

    For more information about this study, contact:

    Rebekah Evans, RN
    859-323-8663
    Email: rastan2@uky.edu

    Return to list »


    FAME 3 (Stanford University)

    Fractional flow reserve versus angiography for multivessel evaluation (FAME) 3 Trail

    PI: Khaled Ziada, MD (UK) and Ahmed Abdel-Latif, MD, PhD (VA)

    • A comparison of fractional flow reserve-guided percutaneous coronary intervention and coronary artery bypass graft surgery in patients with multivessel coronary artery disease

    For more information about this study, contact:

    Caroline Rodgers
    859-323-1082
    Email: Caroline.rodgers@uky.edu

    Return to list »


    TWILIGHT (Mt. Sinai Medical School)

    Ticagrelor With Aspirin or Alone in High-Risk Patients After Coronary Intervention

    PI: David Moliterno, MD

    • To determine the impact of ticagrelor alone vs. ticagrelor plus aspirin in reducing clinically relevant bleeding and ischemic adverse events among high-risk patients who had PCI with at least one drug-eluding stent

    For more information about this study, contact:

    Alexandra Telfair-Hull
    859-218-2880
    Email: Alexandra.hull@uky.edu

    Return to list »


    VOYAGER PAD (Bayer Pharmaceuticals)

    PI: Khaled Ziada, MD

    • Evaluate whether rivaroxaban added to ASA is superior to ASA alone in reducing the risk of major thrombotic vascular events (MI, ischemic stroke, cardiovascular death, major amputation of a vascular etiology) in symptomatic PAD patients undergoing lower extremity revascularization

    For more information about this study, contact:

    Alexandra Telfair-Hull
    859-218-2880
    Email: Alexandra.hull@uky.edu

    Return to list »


    MOMENTUM 3 CAP (St. Jude Medical)

    Multi-Center Study of MagLev Technology in Patients Undergoing MCS Therapy with HeartMate 3™

    PI: Maya Guglin, MD, PhD

    For more information about this study, contact:

    Jennifer Isaacs
    859-323-4738
    Email: Jennifer.isaacs@uky.edu

    Return to list »


    AEGIS 2001 (CSL Berhing)

    A phase 2 study looking at safety of CSL112 in patients following an MI. CSL112 is a novel formulation of apoA-I purified from human plasma and reconstituted to form HDL particles.

    PI: John Kotter, MD

    • Qualified patients who provide consent will receive four 2-hour infusions, 7 days apart, during the active treatment phase

    For more information about this study, contact:

    Caroline Rodgers, RN
    859-323-1082
    Email: Caroline.rodgers@uky.edu

    Return to list »


    DREAM HF (TEVA)

    Efficacy and Safety Study of Allogeneic stem cells in Patients with Chronic Heart Failure Due to Left Ventricular Systolic Dysfunction of Either Ischemic or Nonischemic Etiology

    PI: Ahmed Abdel-Latif, MD, PhD

    • Restoring the function of damaged heart muscle with experimental study product cells

    For more information about this study, contact:

    Heather Shinall
    859-323-5259
    Email: h.shinall@uky.edu

    Return to list »


    Sildenafil HF (GHI)

    Sildenafil in Heart Failure with Reactive Pulmonary Hypertension

    PI: Maya Guglin, MD, PhD

    • To determine whether sildenafil can improve exercise tolerance measured by 6 minute walk distance
    • To determine whether sildenafil can improve hemodynamics, right ventricular function, or quality of life

    For more information about this study, contact:

    Heather Shinall
    859-323-5259
    Email: h.shinall@uky.edu

    Return to list »


    ISCHEMIA (NHLBI/NYUSOM)

    International Study of Comparative Health Effectiveness with Medical and Invasive Approaches invasive strategy ( initial management with cath) vs. conservative strategy (initial management with optimal medical therapy [OMT] and provisional cath if OMT fails) in ischemic patients

    PI: David Booth, MD

    • Patients with at least moderate ischemia on a stress imaging test

    For more information about this study, contact:

    Yvonne Taul, RN
    859-218-1644
    Email: Yvonne.taul@uky.edu

    Return to list »


    CIRT (NHLBI/Brigham and Women’s)

    Cardiovascular Inflammation Reduction Trial

    PI: Adrian Messerli, MD

    • Investigating whether taking low-dose methotrexate reduces heart attacks, strokes, or death in people with type 2 diabetes or metabolic syndrome that have had a heart attack

    For more information about this study, contact:

    Heather Shinall, RN
    859-323-8516
    Email: h.shinall@uky.edu 

    Return to list »


    VEST/VEST Registry (U of CA-SF)

    Non-invasive wearable automatic defibrillator vest will reduce mortality in first 90 days post MI in pts w/ LV dysfunction (≤35%)

    PI: Samy-Claude Elayi, MD

    • STEMI / NSTEMI with EF ≤ 35%
    • LifeVest vs. medical management for 3 months
    • Registry is continuation of data collection for up to 8 years annually

    For more information about this study, contact:

    Yvonne Taul, RN
    859-218-1644
    Email: yvonne.taul@uky.edu

    Return to list »


    Enhance CRT (SJM)

    CRT Implant Strategy using the longest electrical delay for non-LBB patients; randomized, post-market pilot study

    PI: Gustavo Morales, MD

    • Patients with non-left bundle branch block, eligible for bi-ventricular ICD implant

    For more information about this study, contact:

    Rebekah Evans, RN
    859-323-8663
    Email: rastan2@uky.edu

    Return to list »


    ABSORB IV (Abbott)

    A Clinical Evaluation of Absorb™ BVS, the Everolimus Eluting Bioresorbable Vascular Scaffold in the Treatment of Subjects with de Novo Native Coronary Artery Lesions.

    PI: Khaled Ziada, MD

    • Patients with indication for elective LHC and possible PCI

    For more information about this study, contact:

    Caroline Rodgers, RN
    859-323-1082
    Email: caroline.rodgers@uky.edu

    Return to list »


    Spyral HTN ON Meds (Medtronic)

    Global Clinical Study of Renal Denervation with the Symplicity Spyral multi-electrode renal denervation system in patients with Uncontrolled Hypertension on Standard Medical Therapy

    PI: Khaled Ziada, MD

    For more information about this study, contact:

    Heather Shinall
    859-323-5259
    Email: h.shinall@uky.edu 

    Return to list »


    Spyral HTN OFF Meds (Medtronic)

    Global Clinical Study of Renal Denervation with the Symplicity Spyral multi-electrode renal denervation system in patients with Uncontrolled Hypertension in the absence of antihypertensive medications

    PI: Khaled Ziada, MD

    For more information about this study, contact:

    Heather Shinall
    859-323-5259
    Email: h.shinall@uky.edu 

    Return to list »

  • Referrals

    The Gill Heart Institute serves as a local referral center for the treatment of cardiovascular diseases. To refer a patient for any of our areas of service expertise, call UK•MDs at 800-888-5533..

  • gill-map

    Gill Heart Institute Outreach sites (PDF, 549 KB) »

    Cardiology

    Clark Regional Medical Center | Directions »
    Winchester, KY 
    Call 859-323-0295 or toll-free 1-877-700-5479 for appointments

    Georgetown Community Hospital | Directions »
    Georgetown, KY 
    Call 859-323-0295 or toll-free 1-877-700-5479 for appointments

    Norton Audubon Hospital | Directions »
    (Heart failure, Cardiac transplant and Mechanical support)
    Louisville, KY
    Call 859-323-0295 or toll-free 1-877-700-5479 for appointments

    Rockcastle Regional Hospital | Directions »
    Mt Vernon, KY 
    Call 859-323-0295 or toll-free 1-877-700-5479 for appointments

    St. Claire Regional Medical Center | Directions »
    (electrophysiology only)
    Morehead, KY 
    Call 859-323-0295 or toll-free 1-877-700-5479 for appointments

    Cardiothoracic Surgery

    For appointments in the following regions, call 859-323-6494: 

    • Boyle County
    • Harrison County
    • Rockcastle County

    Vascular Surgery

    For appointments in the following regions, call 859-257-3253:

    • Danville 
    • Prestonsburg