UK HealthCare logo

Practice areas

  • Genitourinary and Prostate Cancer Team
  • Living Donor Kidney Transplant
  • Urology

Faculty rank

Professor of Urology

Clinic information

Clinical interests

  • Kidney Transplantation
  • Minimally Invasive Surgery, Including Robotic Assisted Procedures
  • Prostate Cancer
  • Renal Cancer
  • Urologic Oncology
  • Urological Surgery

Education

Degree

Indiana University, School of Medicine, Indianapolis

Residency

Jefferson Medical College, Philadelphia

Fellowship

National Institutes of Health-National Cancer Institute, Bethesda, Md.

Certifications or Special training

American Board of Urology
Fellow of the American College of Surgeons

Additional information

Profile

My name is Stephen Strup; I am the James F. Glenn Professor and Chief of Urology at the University of Kentucky. I am a native of Northwest Ohio and attended DePauw University, graduating Summa Cum Laude in 1984. I received my medical degree from the University of Indiana in 1988. I completed a residency in Urology in 1994 at Thomas Jefferson University in Philadelphia and then completed an Urologic oncology fellowship in 1996 at the National Cancer Institute in Bethesda, Maryland. I returned to Thomas Jefferson University where I was one of the early adopters of the Hand-assisted laparoscopic nephrectomy and laparoscopic radical prostatectomy techniques.

In 2003, I moved to the University of Kentucky in Lexington, where I was appointed the Director of Minimally invasive urologic surgery and, in 2006, residency program director. I was then named the James F. Glenn Chief of Urology in 2007. My clinical interests include Urologic Oncology, minimally invasive and robotic surgery, and living donor nephrectomy.

Research/Publications

  1. Hensley PJ, Zetter D, Horbinski CM, Strup SE, Kyprianou N. Association of Epithelial-Mesenchymal-Transition and Nuclear Cofilin with Advanced Urothelial Cancer. Hum Pathol. 2016 Jul 8.
    View in: PubMed
  2. Lacy JM, Cavallini M, Bylund JR, Strup SE, Preston DM. Trends in the management of male urethral stricture disease in the veteran population. Urology. 2014 Dec;84(6):1506-9.
    View in: PubMed
  3. Bylund JR, Qiong H, Crispen PL, Venkatesh R, Strup SE. Association of clinical and radiographic features with perinephric "sticky" fat. J Endourol. 2013 Mar;27(3):370-3.
    View in: PubMed
  4. Grant C, Lacy JM, Strup SE. A 22-year-old female with invasive epithelioid angiomyolipoma and tumor thrombus into the inferior vena cava: case report and literature review. Case Rep Urol. 2013;2013:730369.
    View in: PubMed
  5. Bylund JR, Gayheart D, Fleming T, Venkatesh R, Preston DM, Strup SE, Crispen PL. Association of Tumor Size, Location, R.E.N.A.L., PADUA and Centrality Index Score with Perioperative Outcomes and Postoperative Renal Function. J Urol. 2012 Nov; 188(5):1684-9. PMID: 22998902.
    View in: PubMed
  6. Strup SE. Editorial comment. Urology. 2012 Sep; 80(3):606-7; author reply 607. PMID: 22818565.
    View in: PubMed
  7. Matnani RG, Patel RK, Strup SE, Karabakhtsian RG. 5q Minus Myelodysplasia Associated with Multiple Epithelioid Granulomas within Conventional Renal Cell Carcinoma. Case Report Pathol. 2012; 2012:138126. PMID: 22934211.
    View in: PubMed
  8. Korrect GS, Kesler MV, Strup SE. Aggressive angiomyxoma presenting as urinary retention in a male: a case report and literature review. Can J Urol. 2011 Oct; 18(5):5908-10. PMID: 22018154.
    View in: PubMed
  9. Bylund JR, Clark CJ, Crispen PL, Lagrange CA, Strup SE. Hand-assisted laparoscopic partial nephrectomy without formal collecting system closure: perioperative outcomes in 104 consecutive patients. J Endourol. 2011 Dec; 25(12):1853-7. PMID: 21864024.
    View in: PubMed
  10. Page JB, Davenport DL, Unnikrishnan R, Crispen PL, Venkatesh R, Strup SE. Temporal relationship between positive margin rate after laparoscopic radical prostatectomy and surgical training. Urology. 2011 Mar; 77(3):626-30. PMID: 21146859.
    View in: PubMed
  11. Carswell CM, Lio CH, Grant R, Klein MI, Clarke D, Seales WB, Strup S. Hands-free administration of subjective workload scales: acceptability in a surgical training environment. Appl Ergon. 2010 Dec; 42(1):138-45. PMID: 20630495.
    View in: PubMed
  12. Strup SE. Editorial comment. J Urol. 2010 May; 183(5):1871; discussion 1872. PMID: 20303105.
    View in: PubMed
  13. Strup SE. Editorial comment. J Urol. 2010 Apr; 183(4):1335-6. PMID: 20171664.
    View in: PubMed
  14. Han Q, Strup SE, Carswell MC, Clarke D, Seales WB. Model completion via deformation cloning based on an explicit global deformation model. Med Image Comput Comput Assist Interv. 2009; 12(Pt 2):1067-74. PMID: 20426217.
    View in: PubMed
  15. Field M, Clarke D, Strup S, Seales WB. Stereo endoscopy as a 3-D measurement tool. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:5748-51. PMID: 19963650.
    View in: PubMed
  16. Trabulsi EJ, Linden RA, Gomella LG, McGinnis DE, Strup SE, Lallas CD. The addition of robotic surgery to an established laparoscopic radical prostatectomy program: effect on positive surgical margins. Can J Urol. 2008 Apr; 15(2):3994-9. PMID: 18405448.
    View in: PubMed
  17. LaGrange CA, Clark CJ, Gerber EW, Strup SE. Evaluation of three laparoscopic modalities: robotics versus three-dimensional vision laparoscopy versus standard laparoscopy. J Endourol. 2008 Mar; 22(3):511-6. PMID: 18269320.
    View in: PubMed
  18. Zhu ML, Partin JV, Bruckheimer EM, Strup SE, Kyprianou N. TGF-beta signaling and androgen receptor status determine apoptotic cross-talk in human prostate cancer cells. Prostate. 2008 Feb 15; 68(3):287-95. PMID: 18163430.
    View in: PubMed
  19. Brown JA, Chenven E, Looney SW, Miller KM, Strup SE, Bagley DH, Gomella LG. Hand-assisted laparoscopic nephroureterectomy (HALNU): an assessment of the impact of obesity in 50 procedures. J Laparoendosc Adv Surg Tech A. 2008 Feb; 18(1):61-8. PMID: 18266577.
    View in: PubMed
  20. LaGrange CA, Gerber EW, Garrett JE, Lele SM, Strup SE. Interstitial laser ablation of the kidney: acute and chronic porcine study using new-generation diffuser tip fiber. J Endourol. 2007 Nov; 21(11):1387-91. PMID: 18042035.
    View in: PubMed
  21. LaGrange CA, Lele SM, Strup SE. Renal cell carcinoma associated with TFE3 gene fusion in an elderly woman. Urology. 2007 Sep; 70(3):590.e11-2. PMID: 17905124.
    View in: PubMed
  22. Jeon H, Johnston TD, Strup SE, Ibrahim M, Ranjan D. University of Kentucky experience with laparoscopic live donor nephrectomy using two different techniques. Int Surg. 2006 Nov-Dec; 91(6):332-5. PMID: 17256431.
    View in: PubMed
  23. Park S, Strup SE, Saboorian H, Cadeddu JA. No evidence of disease after radiofrequency ablation in delayed nephrectomy specimens. Urology. 2006 Nov; 68(5):964-7. PMID: 17113888.
    View in: PubMed
  24. Garrett JE, LaGrange CA, Chenven E, Strup SE. Use of Lowsley tractor during laparoscopic prostatectomy to reduce urethrovesical anastomotic tension. J Endourol. 2006 Mar; 20(3):220-2. PMID: 16548734.
    View in: PubMed
  25. Kalra P, Glassman DT, Gomella LG, Strup SE, McGinnis DE, Simon DR, Chang MF, Byrne DS, Kuo RL. Outcomes of hand-assisted laparoscopic nephrectomy in technically challenging cases. Urology. 2006 Jan; 67(1):45-9. PMID: 16413330.
    View in: PubMed
  26. Halpern EJ, Ramey JR, Strup SE, Frauscher F, McCue P, Gomella LG. Detection of prostate carcinoma with contrast-enhanced sonography using intermittent harmonic imaging. Cancer. 2005 Dec 1; 104(11):2373-83. PMID: 16240450.
    View in: PubMed
  27. Brown JA, Strup SE, Chenven E, Bagley D, Gomella LG. Hand-assisted laparoscopic nephroureterectomy: analysis of distal ureterectomy technique, margin status, and surgical outcomes. Urology. 2005 Dec; 66(6):1192-6. PMID: 16360439.
    View in: PubMed
  28. Strup S, Garrett J, Gomella L, Rowland R. Laparoscopic partial nephrectomy: hand-assisted technique. J Endourol. 2005 May; 19(4):456-9; discussion 459-60. PMID: 15910255.
    View in: PubMed
  29. Brown JA, Garlitz C, Strup SE, Hubosky SG, Gomella L. Laparoscopic radical prostatectomy after neoadjuvant hormonal therapy: an apparently safe and effective procedure. J Laparoendosc Adv Surg Tech A. 2004 Dec; 14(6):335-8. PMID: 15684777.
    View in: PubMed
  30. Strup SE, Hubosky S. Hand-assisted laparoscopic partial nephrectomy. J Endourol. 2004 May; 18(4):345-9. PMID: 15253784.
    View in: PubMed
  31. Brown JA, Hubosky SG, Gomella LG, Strup SE. Hand assisted laparoscopic partial nephrectomy for peripheral and central lesions: a review of 30 consecutive cases. J Urol. 2004 Apr; 171(4):1443-6. PMID: 15017194.
    View in: PubMed
  32. Sambur MR, Strup S, Merton DA, Goldberg BB. Sonographic detection of metastatic renal cell carcinoma to the bladder. J Ultrasound Med. 2004 Mar; 23(3):439-42. PMID: 15055794.
    View in: PubMed
  33. Brown JA, Garlitz C, Gomella LG, McGinnis DE, Diamond SM, Strup SE. Perioperative morbidity of laparoscopic radical prostatectomy compared with open radical retropubic prostatectomy. Urol Oncol. 2004 Mar-Apr; 22(2):102-6. PMID: 15082005.
    View in: PubMed
  34. Chenven ES, McGinnis D, Strup SE. The 3-port laparoscopic pyeloplasty. J Urol. 2004 Mar; 171(3):1050-3. PMID: 14767268.
    View in: PubMed
  35. Bhayani SB, Pavlovich CP, Strup SE, Dahl DM, Landman J, Fabrizio MD, Sundaram CP, Kaouk JH, Su LM. Laparoscopic radical prostatectomy: a multi-institutional study of conversion to open surgery. Urology. 2004 Jan; 63(1):99-102. PMID: 14751358.
    View in: PubMed
  36. Brown JA, Garlitz C, Gomella LG, Hubosky SG, Diamond SM, McGinnis D, Strup SE. Pathologic comparison of laparoscopic versus open radical retropubic prostatectomy specimens. Urology. 2003 Sep; 62(3):481-6. PMID: 12946751.
    View in: PubMed
  37. Lee DI, McGinnis DE, Feld R, Strup SE. Retroperitoneal laparoscopic cryoablation of small renal tumors: intermediate results. Urology. 2003 Jan; 61(1):83-8. PMID: 12559272.
    View in: PubMed
  38. Halpern EJ, Frauscher F, Strup SE, Nazarian LN, O'Kane P, Gomella LG. Prostate: high-frequency Doppler US imaging for cancer detection. Radiology. 2002 Oct; 225(1):71-7. PMID: 12354987.
    View in: PubMed
  39. Halpern EJ, Frauscher F, Forsberg F, Strup SE, Nazarian LN, O'Kane P, Gomella LG. High-frequency Doppler US of the prostate: effect of patient position. Radiology. 2002 Mar; 222(3):634-9. PMID: 11867778.
    View in: PubMed
  40. Lee D, Trabulsi E, McGinnis D, Strup S, Gomella LG, Bagley D. Totally endoscopic management of upper tract transitional-cell carcinoma. J Endourol. 2002 Feb; 16(1):37-41. PMID: 11890449.
    View in: PubMed
  41. Chen CT, Valicenti RK, Lu J, Derose T, Dicker AP, Strup SE, Mulholland SG, Hirsch IH, McGinnis DE, Gomella LG. Does hormonal therapy influence sexual function in men receiving 3D conformal radiation therapy for prostate cancer? Int J Radiat Oncol Biol Phys. 2001 Jul 1; 50(3):591-5. PMID: 11395224.
    View in: PubMed
  42. McGinnis DE, Trabulsi EJ, Gomella LG, Strup SE. Hand-assisted laparoscopic nephroureterectomy: description of technique. Tech Urol. 2001 Mar; 7(1):7-11. PMID: 11272685.
    View in: PubMed
  43. el-Gabry EA, Halpern EJ, Strup SE, Gomella LG. Imaging prostate cancer: current and future applications. Oncology (Williston Park). 2001 Mar; 15(3):325-36; discussion 339-42. PMID: 11301831.
    View in: PubMed
  44. McGinnis DE, Gomella LG, Strup SE. Comparison and clinical evaluation of hand-assist devices for hand-assisted laparoscopy. Tech Urol. 2001 Mar; 7(1):57-61. PMID: 11272681.
    View in: PubMed
  45. Chen CT, Waterman FM, Valicenti RK, Gomella LG, Strup SE, Dicker AP. Dosimetric analysis of urinary morbidity following prostate brachytherapy (125I vs. 103Pd) combined with external beam radiation therapy. Int J Cancer. 2001; 96 Suppl:83-8. PMID: 11992390.
    View in: PubMed
  46. Rivas DA, Bagley D, Gomella LG, Hirsch IH, Hubert C, Lombardo S, McGinnis DE, Mulholland SG, Shenot PJ, Strup SE, Vasavada SP. Transurethral microwave thermotherapy of the prostate without intravenous sedation: results of a single United States center using both low- and high-energy protocols. TJUH TUMT Study Group. Tech Urol. 2000 Dec; 6(4):282-7. PMID: 11108567.
    View in: PubMed
  47. McGinnis DE, Strup SE, Gomella LG. Management of hemorrhage during laparoscopy. J Endourol. 2000 Dec; 14(10):915-20. PMID: 11206627.
    View in: PubMed
  48. El-Gabry EA, Strup SE, Gomella LG. Undetectable prostate-specific antigen response with bicalutamide withdrawal phenomenon. Tech Urol. 2000 Sep; 6(3):221-2. PMID: 10963494.
    View in: PubMed
  49. Baffa R, Reiss K, El-Gabry EA, Sedor J, Moy ML, Shupp-Byrne D, Strup SE, Hauck WW, Baserga R, Gomella LG. Low serum insulin-like growth factor 1 (IGF-1): a significant association with prostate cancer. Tech Urol. 2000 Sep; 6(3):236-9. PMID: 10963500.
    View in: PubMed
  50. Valicenti RK, Gomella LG, El-Gabry EA, Myers R, Nathan F, Strup S, Dicker A, McGinnis DE, Cardi G, Baltish M, Simirgliano M, Vizzard A, Mulholland SG. The multidisciplinary clinic approach to prostate cancer counseling and treatment. Semin Urol Oncol. 2000 Aug; 18(3):188-91. PMID: 10975490.
    View in: PubMed
  51. El-Gabry EA, Strup SE, Gomella LG. Deciding on radical prostatectomy: the physician's perspective. Semin Urol Oncol. 2000 Aug; 18(3):205-13. PMID: 10975493.
    View in: PubMed
  52. Dicker AP, Figura AT, Waterman FM, Valicenti RK, Strup SE, Gomella LG. Is there a role for antibiotic prophylaxis in transperineal interstitial permanent prostate brachytherapy? Tech Urol. 2000 Jun; 6(2):104-8. PMID: 10798809.
    View in: PubMed
  53. Halpern EJ, Strup SE. Using gray-scale and color and power Doppler sonography to detect prostatic cancer. AJR Am J Roentgenol. 2000 Mar; 174(3):623-7. PMID: 10701599.
    View in: PubMed
  54. Baffa R, Gomella LG, Vecchione A, Bassi P, Mimori K, Sedor J, Calviello CM, Gardiman M, Minimo C, Strup SE, McCue PA, Kovatich AJ, Pagano F, Huebner K, Croce CM. Loss of FHIT expression in transitional cell carcinoma of the urinary bladder. Am J Pathol. 2000 Feb; 156(2):419-24. PMID: 10666370.
    View in: PubMed
  55. Feld RI, McGinnis DE, Needleman L, Segal SR, Strup SE, Nazarian LN. A novel application for the end-fire sonographic probe: guidance during cryoablation of renal masses. AJR Am J Roentgenol. 1999 Sep; 173(3):652-4. PMID: 10470896.
    View in: PubMed
  56. Valicenti RK, Gomella LG, Ismail M, Strup SE, Mulholland SG, Dicker AP, Petersen RO, Newschaffer CJ. The efficacy of early adjuvant radiation therapy for pT3N0 prostate cancer: a matched-pair analysis. Int J Radiat Oncol Biol Phys. 1999 Aug 1; 45(1):53-8. PMID: 10477006.
    View in: PubMed
  57. Strup SE, Pozzatti RO, Florence CD, Emmert-Buck MR, Duray PH, Liotta LA, Bostwick DG, Linehan WM, Vocke CD. Chromosome 16 allelic loss analysis of a large set of microdissected prostate carcinomas. J Urol. 1999 Aug; 162(2):590-4. PMID: 10411092.
    View in: PubMed
  58. Fabrizio MD, Strup SE, Filmer RB, Noseworthy J, Gearhart JP. Duplicate bladder exstrophy: a unique approach to initial repair. Urology. 1999 Feb; 53(2):401-4. PMID: 9933063.
    View in: PubMed
  59. Valicenti RK, Gomella LG, Ismail M, Mulholland SG, Strup S, Petersen RO, Corn BW, Lu JD. Durable efficacy of early postoperative radiation therapy for high-risk pT3N0 prostate cancer: the importance of radiation dose. Urology. 1998 Dec; 52(6):1034-40. PMID: 9836551.
    View in: PubMed
  60. Das A, Strup S, Canfield S, Mulholland SG, Gomella LG. Utilization of autologous blood donation during radical retropubic prostatectomy. Tech Urol. 1998 Sep; 4(3):131-5. PMID: 9800890.
    View in: PubMed
  61. Chuaqui RF, Englert CR, Strup SE, Vocke CD, Zhuang Z, Duray PH, Bostwick DG, Linehan WM, Liotta LA, Emmert-Buck MR. Identification of a novel transcript up-regulated in a clinically aggressive prostate carcinoma. Urology. 1997 Aug; 50(2):302-7. PMID: 9255310.
    View in: PubMed
  62. Chancellor MB, Strup S, Rivas DA, Watanabe T, Gomella LG. Rectus urethromyoplasty of radical prostatectomy anastomosis decreases postoperative incontinence and anastomotic stricture; technique and preliminary results. J Urol. 1997 Jan; 157(1):371-5. PMID: 8976300.
    View in: PubMed
  63. Strup SE, Bagley DH. Endoscopic ureteroneocystostomy for complete obstruction at the ureterovesical junction. J Urol. 1996 Aug; 156(2 Pt 1):360-2. PMID: 8683679.
    View in: PubMed
  64. Vocke CD, Pozzatti RO, Bostwick DG, Florence CD, Jennings SB, Strup SE, Duray PH, Liotta LA, Emmert-Buck MR, Linehan WM. Analysis of 99 microdissected prostate carcinomas reveals a high frequency of allelic loss on chromosome 8p12-21. Cancer Res. 1996 May 15; 56(10):2411-6. PMID: 8625320.
    View in: PubMed
  65. Strup SE, Sindelar WF, Walther MM. The use of transureteroureterostomy in the management of complex ureteral problems. J Urol. 1996 May; 155(5):1572-4. PMID: 8627825.
    View in: PubMed
  66. Gomella LG, Strup SE, Young C, Barbot D. Laparoscopic pelvic lymphadenectomy combined with inguinal herniorrhaphy. Tech Urol. 1995; 1(1):49-53. PMID: 9118368.
    View in: PubMed
  67. Grasso M, Beaghler M, Bagley DH, Strup S. Actively deflectable, flexible cystoscopes: no longer solely a diagnostic instrument. J Endourol. 1993 Dec; 7(6):527-30. PMID: 8124350.
    View in: PubMed
  68. Chancellor MB, Erhard MJ, Strup S, Tammela TL. Bladder augmentation using the stomach in spinal cord injured patients with impaired renal function. Arch Phys Med Rehabil. 1993 Nov; 74(11):1222-4. PMID: 8239968.
    View in: PubMed
  69. Strup SE, Gudziak M, Mulholland SG, Gomella LG. The effect of intermittent pneumatic compression devices on intraoperative blood loss during radical prostatectomy and radical cystectomy. J Urol. 1993 Oct; 150(4):1176-8. PMID: 8371383.
    View in: PubMed
  70. Chancellor MB, Karasick S, Strup S, Abdill CK, Hirsch IH, Staas WE. Transurethral balloon dilation of the external urinary sphincter: effectiveness in spinal cord-injured men with detrusor-external urethral sphincter dyssynergia. Radiology. 1993 May; 187(2):557-60. PMID: 8475307.
    View in: PubMed
  71. Gomella LG, Strup SE. History of laparoscopy: urology's perspective. J Endourol. 1993 Feb; 7(1):1-5. PMID: 8481714.
    View in: PubMed
  72. Foster RS, Mahomed Y, Bihrle R, Strup S. Use of a caval-atrial shunt for resection of a caval tumor thrombus in renal cell carcinoma. J Urol. 1988 Dec; 140(6):1370-1. PMID: 3193498.
    View in: PubMed