John Lee Villano, MD, PhD

Director, Clinical Neuro-Oncology Research Program

Clinical interests

  • Brain Tumors
  • Neuro-Oncology

John Lee Villano, MD, PhD

Director, Clinical Neuro-Oncology Research Program


My name is John L. Villano; I specialize in the treatment of brain cancers. I will advance UK HealthCare's Clinical Neuro-Oncology Research Program, serving as its director. UK HealthCare has a history of being a world-class neuro-oncology program, and I will help carry this tradition into the future.

Previously, I served as the director of medical neuro-oncology at the University of Illinois Medical Center. I earned a medical degree and doctor of philosophy at the University of Texas Southwestern Medical School at Dallas and trained in neurology at the University of Michigan. I also completed a fellowship in hematology/oncology at the University of Chicago. I am a former American Society of Clinical Oncology track leader for CNS tumors. Currently, I am on the board of the Central Brain Tumor Registry US. I am also a member of the Neuro-Oncology Committee in the cooperative group ALLIANCE and a Society of Neuro-Oncology committee member.

Faculty rank

Professor of Medicine


University of Texas Southwestern Medical Center, Dallas

Neurology, University of Michigan Medical School, Ann Arbor
Internal Medicine, Cook County Hospital, Chicago

Hematology/Oncology, University of Chicago

Certifications or Special training
American Board of Internal Medicine
American Board of Internal Medicine, Medical Oncology

Brain Cancer

Multidisciplinary Clinic

Markey Cancer Center
Whitney-Hendrickson Building
First Floor
800 Rose St.
Lexington KY 40536-0098

This is a clinic of the University of Kentucky Hospital, also known as UK Albert B. Chandler Hospital. Read more »

Medical Oncology

Multidisciplinary Clinic

Markey Cancer Center
Whitney-Hendrickson Building
Room 134
800 Rose St.
Lexington KY 40536-0098

Call 859-323-5275
Call 859-323-8043
Fax 859-257-3757

Directions to Markey Cancer Center »

UK HealthCare accepts many forms of insurance. See list of insurers »


Recent Publications

(Five most recent publications from PubMed via an automated list based on the provider’s ID and the University of Kentucky.)
  1. Gabay MP, Wirth SM, Stachnik JM, Overley CL, Long KE, Bressler LR, Villano JL.
    Oral Targeted Therapies and Central Nervous System (CNS) Metastases.
    CNS Drugs. 2015 Nov;29(11):935-52.
  2. Dolecek TA, Dressler EV, Thakkar JP, Liu M, Al-Qaisi A, Villano JL.
    Epidemiology of meningiomas post-Public Law 107-206: The Benign Brain Tumor Cancer Registries Amendment Act.
    Cancer. 2015 Jul 15;121(14):2400-10.
  3. Villano JL, Durbin EB, Normandeau C, Thakkar JP, Moirangthem V, Davis FG.
    Incidence of brain metastasis at initial presentation of lung cancer.
    Neuro Oncol. 2015 Jan;17(1):122-8.
  4. Thakkar JP, Dolecek TA, Horbinski C, Ostrom QT, Lightner DD, Barnholtz-Sloan JS, Villano JL.
    Epidemiologic and molecular prognostic review of glioblastoma.
    Cancer Epidemiol Biomarkers Prev. 2014 Oct;23(10):1985-96.
  5. Villano JL, Pittman T.
    Straying from the path in neuro-oncology.
    Neuro Oncol. 2014 Aug;16(8):1155-6.

View this provider on PubMed