Roberto Gedaly is a practicing transplant surgeon and clinician-scientist who has earned both national and international recognition for his work with infectious complications, including hepatitis and patients undergoing liver resection and liver transplantation. His research has focused on immunosuppressive strategies in liver transplantation. His currently seeks to define markers and prognostic indicators of hepatocellular carcinoma in an attempt to determine more effective therapies.
After receiving a medical degree from the Universidad Central de Venezuela in Caracas, Venezuela in 1990, Gedaly completed his general surgery residency at the University Hospital of Caracas. He then completed a two-year fellowship in hepatobiliary and transplantation service at Beth Israel Deaconess Medical Center through the Harvard Medical School in Boston; a one-year fellowship in liver and GI transplantation at the Jackson Memorial Hospital at the University of Miami School of Medicine in Miami, Fla.; and a two-year fellowship in transplantation at the Methodist Hospital at the University of Tennessee in Memphis. Gedaly joined the University of Kentucky in 2006. He is actively engaged in medical and surgical societies, is a frequently invited guest speaker at meetings worldwide and has authored numerous publications appearing in leading peer-review journals and text books.
Associate Professor of Surgery
Central University of Venezuela, Razetti School of Medicine, Caracas, Venezuela
University Hospital of Caracas, Central University of Venezuela, Caracas, Venezuela
Deaconess Hospital, Harvard University, Boston
Jackson Memorial Hospital, University of Miami, Fla.
Methodist Hospital, University of Tennessee, Memphis
Certifications or Special training
Member, American Association for the Study of Liver Diseases
Member, American Society of Transplant Surgeons
Member, American Society of Transplant Physicians
Member, International Liver Transplantation Society
Member, Venezuelan Surgical Society
Member, Kentucky Organ Donor Affiliates (KODA) Executive Board of Directors
Member, KODA Advisory Committee
Member, University of Kentucky Organ Transplant Evaluation Committees (liver, pancreas, kidney)
Pediatric Kidney Transplant
UK Transplant Center
Third Floor, Wing D, Room J301
740 S. Limestone
Lexington KY 40536-0284
Markey Cancer Center
800 Rose St.
Lexington KY 40536-0098
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Roberto Gedaly, Roberto Galuppo, Yolanda Musgrave, Paul Angulo, Jonathan Hundley,
Malay Shah, Michael F. Daily, Changguo Chen, Donald A. Cohen, Brett T. Spear and B. Mark
Evers. PKI-587 and Sorafenib Alone and in Combination on Inhibition of Liver Cancer Stem
Cell Proliferation. J. Surg. Res 2013 E-Pub before Print
Gedaly R, Angulo P, Chen C, Creasy KT, Spear BT, Hundley J, et al. The Role of PI3K/mTOR
Inhibition in Combination with Sorafenib in Hepatocellular Carcinoma Treatment. Anticancer
Res 32:2531-2536, 2012
Gedaly R, Angulo P, Hundley J, Daily MF, Chen C, Evers BM. PKI-587 and Sorafenib Targeting
PI3K/AKT/mTOR and Ras/Raf/MAPK Pathways Synergistically Inhibit HCC Cell Proliferation. J
Surg Res 176: 542-548, 2012
Gedaly R, Angulo P, Hundley J, Daily MF, Chen C, Koch A, and Evers BM: PI-103 and
sorafenib inhibit hepatocellular carcinoma cell proliferation by blocking Ras/Raf/MAPK and
PI3K/AKT/mTOR pathways. Anticancer Res 30:4951-4958, 2010
Gedaly R, McHugh PP, Johnston TD, Jeon H, Koch A, Clifford TM, Ranjan D. Predictors
of relapse to alcohol and illicit drugs after liver transplantation for alcoholic liver disease.
Transplantation 86(8):1090-1095, 2008
A Patient's story - Surviving Organ Failure, Transplant & Cancer
Teresa Schladt’s life-size selfportrait, painted in 2013 during an art therapy project for organ transplant patients at UK Chandler Hospital, shows the Lexington woman springing into a star-filled, midnight-blue sky. Inside each star is the name of someone who supported her through her 2007 liver transplant and cancer treatment and in the days since. There are many, many stars and many, many names, among them family, friends and more than a few UK HealthCare medical professionals.
As the 55-year-old looks at the painting and considers the life she has, she is quick to remind others and herself, “I am one of the luckiest people you have ever met. I am happy with life.”
Read more of Teresa's story »