Christopher P. DeSimone, MD

Director of Robotic Surgery
Associate Residency Director

Clinical interests

  • Cervical Cancer
  • Complex Pelvic Surgery
  • Endometrial Cancer
  • Gynecologic Oncology
  • Minimally Invasive Surgery, Including Robotic Assisted Procedures
  • Ovarian Cancer Surgery

Christopher P. DeSimone, MD

Director of Robotic Surgery
Associate Residency Director

Biography

My name is Christopher P. DeSimone; I attended Boston University and graduated magna cum laude with a Bachelor of Arts in art history. I graduated from the University of Kentucky, College of Medicine with high distinction. I completed an OB-GYN residency and Gynecologic Oncology fellowship at the University of Kentucky, College of Medicine. I am board certified by the American Board of Obstetrics and Gynecology in OB-GYN and Gynecologic Oncology.

I am the director of robotic surgery and associate residency director for OB-GYN. I serve on the admissions committee for the University of Kentucky, College of Medicine and is a national board examiner for the American Board of Obstetrics and Gynecology. My medical interests include robotic surgery, endometrial cancer and ovarian cancer. 

Faculty rank

Associate Professor of Obstetrics and Gynecology

Education

Degree
University of Kentucky, College of Medicine, Lexington

Residency
University of Kentucky, Lexington

Fellowship
University of Kentucky, Lexington

Certifications or Special training
American Board of Obstetrics and Gynecology
American Board of Obstetrics and Gynecology, Gynecologic Oncology

Gynecologic Oncology

Gynecologic Oncology Clinic

Markey Cancer Center
Whitney-Hendrickson Building
Third Floor, Room 330A
800 Rose St.
Lexington KY 40536-0098

Call 859-323-5553
Call 866-340-4488
Fax 859-323-1602

Directions to Markey Cancer Center »


UK HealthCare accepts many forms of insurance. See list of insurers »

 
  1. Lefringhouse JR, Neward E, Ueland FR, Baldwin LA, Miller RW, DeSimone CP, Kryscio RJ, van Nagell JR, Pavlik EJ. Probability of fallopian tube and ovarian detection with transvaginal ultrasonography in normal women. Womens Health (Lond). 2016 Jun;12(3):303-11.
    View in: PubMed
  2. Elder JW, Pavlik EJ, Long A, Miller RW, DeSimone CP, Hoff JT, Ueland WR, Kryscio RJ, van Nagell JR, Ueland FR. Serial ultrasonographic evaluation of ovarian abnormalities with a morphology index. Gynecol Oncol. 2014 Oct;135(1):8-12.
    View in: PubMed
  3. Pavlik EJ, Ueland FR, Miller RW, Ubellacker JM, DeSimone CP, Elder J, Hoff J, Baldwin L, Kryscio RJ, van Nagell JR. Frequency and disposition of ovarian abnormalities followed with serial transvaginal ultrasonography. Obstet Gynecol. 2013 Aug;122(2 Pt 1):210-7.
    View in: PubMed
  4. Slone S, White C, Shelton B, Van Meter E, Desimone C, Schoenberg N, Dignan M. Inconsistencies between medical records and patient-reported recommendations for follow-up after abnormal pap tests. J Womens Health (Larchmt). 2013 Feb; 22(2):147-52. PMID: 23145889.
    View in: PubMed
  5. Baldwin LA, Huang B, Miller RW, Tucker T, Goodrich ST, Podzielinski I, DeSimone CP, Ueland FR, van Nagell JR, Seamon LG. Ten-year relative survival for epithelial ovarian cancer. Obstet Gynecol. 2012 Sep; 120(3):612-8. PMID: 22914471.
    View in: PubMed
  6. Arora R, Eble JN, Pierce HH, Crispen PL, DeSimone CP, Lee EY, Karabakhtsian RG. Bilateral ovarian steroid cell tumours and massive macronodular adrenocortical disease in a patient with hereditary leiomyomatosis and renal cell cancer syndrome. Pathology. 2012 Jun; 44(4):360-3. PMID: 22565324.
    View in: PubMed
  7. McDonald JM, Karabakhtsian RG, Pierce HH, Iocono JA, Desimone CP, Bayliff SL, Ueland FR. Small cell carcinoma of the ovary of hypercalcemic type: a case report. J Pediatr Surg. 2012 Mar; 47(3):588-92. PMID: 22424359.
    View in: PubMed
  8. van Nagell JR, Miller RW, DeSimone CP, Ueland FR, Podzielinski I, Goodrich ST, Elder JW, Huang B, Kryscio RJ, Pavlik EJ. Long-term survival of women with epithelial ovarian cancer detected by ultrasonographic screening. Obstet Gynecol. 2011 Dec; 118(6):1212-21. PMID: 22105249.
    View in: PubMed
  9. Seamon LG, Tarrant RL, Fleming ST, Vanderpool RC, Pachtman S, Podzielinski I, Branscum AJ, Feddock JM, Randall ME, Desimone CP. Cervical cancer survival for patients referred to a tertiary care center in Kentucky. Gynecol Oncol. 2011 Dec; 123(3):565-70. PMID: 21963092.
    View in: PubMed
  10. DeSimone CP, Day ME, Dietrich CS, Tovar MM, Modesitt SC. Risk for residual adenocarcinoma in situ or cervical adenocarcinoma in women undergoing loop electrosurgical excision procedure/conization for adenocarcinoma in situ. J Reprod Med. 2011 Sep-Oct; 56(9-10):376-80. PMID: 22010519.
    View in: PubMed
  11. Rimel BJ, Ferda A, Erwin J, Dewdney SB, Seamon L, Gao F, DeSimone C, Cotney KK, Huh W, Massad LS. Cervicovaginal cytology in the detection of recurrence after cervical cancer treatment. Obstet Gynecol. 2011 Sep; 118(3):548-53. PMID: 21860282.
    View in: PubMed
  12. Ware Miller R, Smith A, DeSimone CP, Seamon L, Goodrich S, Podzielinski I, Sokoll L, van Nagell JR, Zhang Z, Ueland FR. Performance of the American College of Obstetricians and Gynecologists' ovarian tumor referral guidelines with a multivariate index assay. Obstet Gynecol. 2011 Jun; 117(6):1298-306. PMID: 21555961.
    View in: PubMed
  13. Ueland FR, Desimone CP, Seamon LG, Miller RA, Goodrich S, Podzielinski I, Sokoll L, Smith A, van Nagell JR, Zhang Z. Effectiveness of a multivariate index assay in the preoperative assessment of ovarian tumors. Obstet Gynecol. 2011 Jun; 117(6):1289-97. PMID: 21606739.
    View in: PubMed
  14. Ferriss JS, Brix W, Tambouret R, DeSimone CP, Stoler M, Modesitt SC. Cervical stromal invasion predicting survival in endometrial cancer. Obstet Gynecol. 2010 Nov; 116(5):1035-41. PMID: 20966686.
    View in: PubMed
  15. Saunders BA, Podzielinski I, Ware RA, Goodrich S, DeSimone CP, Ueland FR, Seamon L, Ubellacker J, Pavlik EJ, Kryscio RJ, van Nagell JR. Risk of malignancy in sonographically confirmed septated cystic ovarian tumors. Gynecol Oncol. 2010 Sep; 118(3):278-82. PMID: 20554314.
    View in: PubMed
  16. McDonald JM, Doran S, DeSimone CP, Ueland FR, DePriest PD, Ware RA, Saunders BA, Pavlik EJ, Goodrich S, Kryscio RJ, van Nagell JR. Predicting risk of malignancy in adnexal masses. Obstet Gynecol. 2010 Apr; 115(4):687-94. PMID: 20308826.
    View in: PubMed
  17. Dietrich CS, Greenberg VL, DeSimone CP, Modesitt SC, van Nagell JR, Craven R, Zimmer SG. Suberoylanilide hydroxamic acid (SAHA) potentiates paclitaxel-induced apoptosis in ovarian cancer cell lines. Gynecol Oncol. 2010 Jan; 116(1):126-30. PMID: 19875160.
    View in: PubMed
  18. Coker AL, Desimone CP, Eggleston KS, White AL, Williams M. Ethnic disparities in cervical cancer survival among Texas women. J Womens Health (Larchmt). 2009 Oct; 18(10):1577-83. PMID: 19788363.
    View in: PubMed
  19. Pavlik EJ, Saunders BA, Doran S, McHugh KW, Ueland FR, Desimone CP, Depriest PD, Ware RA, Kryscio RJ, van Nagell JR. The search for meaning-Symptoms and transvaginal sonography screening for ovarian cancer: predicting malignancy. Cancer. 2009 Aug 15; 115(16):3689-98. PMID: 19603478.
    View in: PubMed
  20. Coker AL, Hopenhayn C, DeSimone CP, Bush HM, Crofford L. Violence against Women Raises Risk of Cervical Cancer. J Womens Health (Larchmt). 2009 Aug; 18(8):1179-85. PMID: 19630537.
    View in: PubMed
  21. Coker AL, DeSimone CP, Eggleston KS, Hopenhayn C, Nee J, Tucker T. Smoking and survival among Kentucky women diagnosed with invasive cervical cancer: 1995-2005. Gynecol Oncol. 2009 Feb; 112(2):365-9. PMID: 19036421.
    View in: PubMed
  22. Desimone CP, Ueland FR. Gynecologic laparoscopy. Surg Clin North Am. 2008 Apr; 88(2):319-41, vi. PMID: 18381116.
    View in: PubMed
  23. Chalothorn LA, Beeman CS, Ebersole JL, Kluemper GT, Hicks EP, Kryscio RJ, DeSimone CP, Modesitt SC. Hypodontia as a risk marker for epithelial ovarian cancer: a case-controlled study. J Am Dent Assoc. 2008 Feb; 139(2):163-9. PMID: 18245684.
    View in: PubMed
  24. van Nagell JR, DePriest PD, Ueland FR, DeSimone CP, Cooper AL, McDonald JM, Pavlik EJ, Kryscio RJ. Ovarian cancer screening with annual transvaginal sonography: findings of 25,000 women screened. Cancer. 2007 May 1; 109(9):1887-96. PMID: 17373668.
    View in: PubMed
  25. DeSimone CP. Cervical cancer, human papillomavirus and smoking. J Ky Med Assoc. 2007 May; 105(5):212-4. PMID: 17566464.
    View in: PubMed
  26. Dietrich CS, Desimone CP, Modesitt SC, Depriest PD, Ueland FR, Pavlik EJ, Kryscio R, Cibull M, Huh W, Partridge E, Numnum TM, Schilder J, Higgins RV, van Nagell JR. Primary appendiceal cancer: gynecologic manifestations and treatment options. Gynecol Oncol. 2007 Mar; 104(3):602-6. PMID: 17055559.
    View in: PubMed
  27. DeSimone CP, Van Ness JS, Cooper AL, Modesitt SC, DePriest PD, Ueland FR, Pavlik EJ, Kryscio RJ, van Nagell JR. The treatment of lateral T1 and T2 squamous cell carcinomas of the vulva confined to the labium majus or minus. Gynecol Oncol. 2007 Feb; 104(2):390-5. PMID: 17027067.
    View in: PubMed
  28. DeSimone CP, Crisp MP, Ueland FR, DePriest PD, van Nagell JR, Lele SM, Modesitt SC. Concordance of gross surgical and final fixed margins in vulvar intraepithelial neoplasia 3 and vulvar cancer. J Reprod Med. 2006 Aug; 51(8):617-20. PMID: 16967630.
    View in: PubMed
  29. DeSimone CP, Day ME, Tovar MM, Dietrich CS, Eastham ML, Modesitt SC. Rate of pathology from atypical glandular cell Pap tests classified by the Bethesda 2001 nomenclature. Obstet Gynecol. 2006 Jun; 107(6):1285-91. PMID: 16738153.
    View in: PubMed
  30. Ueland FR, Depriest PD, Desimone CP, Pavlik EJ, Lele SM, Kryscio RJ, van Nagell JR. The accuracy of examination under anesthesia and transvaginal sonography in evaluating ovarian size. Gynecol Oncol. 2005 Nov; 99(2):400-3. PMID: 16084576.
    View in: PubMed
  31. Chobanian NH, Greenberg VL, Gass JM, Desimone CP, Van Nagell JR, Zimmer SG. Histone deacetylase inhibitors enhance paclitaxel-induced cell death in ovarian cancer cell lines independent of p53 status. Anticancer Res. 2004 Mar-Apr; 24(2B):539-45. PMID: 15160991.
    View in: PubMed
  32. DeSimone CP, Lele SM, Modesitt SC. Malignant struma ovarii: a case report and analysis of cases reported in the literature with focus on survival and I131 therapy. Gynecol Oncol. 2003 Jun; 89(3):543-8. PMID: 12798728.
    View in: PubMed
  33. DePriest PD, DeSimone CP. Ultrasound screening for the early detection of ovarian cancer. J Clin Oncol. 2003 May 15; 21(10 Suppl):194s-199s. PMID: 12743134.
    View in: PubMed