John A. D'Orazio, MD, PhD

Clinical interests

  • Genetic Cancer Predisposition
  • Melanoma Biology
  • Pediatric Hematology and Oncology

John A. D'Orazio, MD, PhD


My name is John D’Orazio; I received my medical degree from University of Miami, School of Medicine, Miami, Fla. I then completed a Pediatrics residency at the Massachusetts General Hospital, Boston and a Pediatric Hematology/Oncology fellowship at Boston Children’s Hospital and the Dana-Farber Cancer Institute, Boston.

I am board certified by the American Board of Pediatrics in Hematology/Oncology.

Faculty rank

Associate Professor of Pediatrics


University of Miami, School of Medicine, Miami, Fla.

Massachusetts General Hospital, Boston

Dana-Farber Cancer Institute, Boston

Certifications or Special training
American Board of Pediatrics
American Board of Pediatrics, Hematology/Oncology

Pediatric Hematology and Oncology

The DanceBlue Kentucky Children's Hospital Hematology/Oncology Clinic

Kentucky Clinic
Second Floor, Room L230
740 S. Limestone
Lexington KY 40536-0284

Call 859-257-4554
Fax 859-257-8978

Appointments based on need and availability: Thursdays, 8 a.m.- noon or by appointment

Dining, Internet/Wi-Fi, Information desk, Pharmacy services, Wheelchairs

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John D'Orazio Lab

Recent Publications

(Five most recent publications from PubMed via an automated list based on the provider’s ID and the University of Kentucky.)
  1. Wolf Horrell EM, Boulanger MC, D'Orazio JA.
    Melanocortin 1 Receptor: Structure, Function, and Regulation.
    Front Genet. 2016;7:95.
  2. Jarrett SG, Wolf Horrell EM, Boulanger MC, D'Orazio JA.
    Defining the Contribution of MC1R Physiological Ligands to ATR Phosphorylation at Ser435, a Predictor of DNA Repair in Melanocytes.
    J Invest Dermatol. 2015 Dec;135(12):3086-95.
  3. D'Orazio JA.
    Melanocyte UV resistance: Feelin' the endothelin.
    Exp Dermatol. 2015 Jun;24(6):414-5.
  4. Jarrett SG, Wolf Horrell EM, Christian PA, Vanover JC, Boulanger MC, Zou Y, D'Orazio JA.
    PKA-mediated phosphorylation of ATR promotes recruitment of XPA to UV-induced DNA damage.
    Mol Cell. 2014 Jun 19;54(6):999-1011.
  5. Amaro-Ortiz A, Yan B, D'Orazio JA.
    Ultraviolet radiation, aging and the skin: prevention of damage by topical cAMP manipulation.
    Molecules. 2014;19(5):6202-19.

View this provider on PubMed