Lars M. Wagner, MD

Chief, Pediatric Hematology and Oncology

Biography

My name is Lars Wagner; I received my medical degree from University of Kentucky, Lexington. I then completed a fellowship in Pediatric Hematology/Oncology at St. Jude Children's Research Hospital, Memphis, Tenn.

I am is board certified by the American Board of Pediatrics in Hematology/Oncology.

Faculty rank

Professor of Pediatrics

Education

Degree
University of Kentucky, Lexington

Residency
Le Bonheur Children's Medical Center, Memphis, Tenn.

Fellowship
Pediatric Hematology/Oncology, St. Jude Children's Research Hospital, Memphis, Tenn.

Certifications or Special training
American Board of Pediatrics
American Board of Pediatrics, Hematology/Oncology

Pediatric Hematology and Oncology

Long-term Follow-up Clinic

Kentucky Clinic
Second Floor, Wing D
740 S. Limestone
Lexington KY 40536-0284

Call 859-257-4554
Fax 859-257-8978

Appointments based on need and availability: Thursdays, 8 a.m.- noon or by appointment

Amenities
Dining, Internet/Wi-Fi, Information desk, Pharmacy services, Wheelchairs

Kentucky Clinic Map (PDF, 616 KB) »
Directions to Kentucky Clinic Parking »



Pediatric Hematology and Oncology

The DanceBlue Kentucky Children's Hospital Hematology/Oncology Clinic

Kentucky Clinic
Second Floor, Room L230
740 S. Limestone
Lexington KY 40536-0284

Call 859-257-4554
Fax 859-257-8978

Appointments based on need and availability: Thursdays, 8 a.m.- noon or by appointment

Amenities
Dining, Internet/Wi-Fi, Information desk, Pharmacy services, Wheelchairs

Kentucky Clinic Map (PDF, 616 KB) »
Directions to Kentucky Clinic Parking »


UK HealthCare accepts many forms of insurance. See list of insurers »

 
  1. Wagner LM. Fifteen years of irinotecan therapy for pediatric sarcoma: where to next? Clin Sarcoma Res. 2015;5:20.
    View in: PubMed
  2. Wagner LM. Profile of veliparib and its potential in the treatment of solid tumors. Onco Targets Ther. 2015;8:1931-9.
    View in: PubMed
  3. Cost NG, Geller JI, Defoor WR, Wagner LM, Noh PH. A robotic-assisted laparoscopic approach for pediatric renal cell carcinoma allows for both nephron-sparing surgery and extended lymph node dissection. J Pediatr Surg. 2012 Oct; 47(10):1946-50. PMID: 23084214.
    View in: PubMed
  4. Wagner LM, Smolarek TA, Sumegi J, Marmer D. Assessment of minimal residual disease in ewing sarcoma. Sarcoma. 2012; 2012:780129. PMID: 22550426.
    View in: PubMed
  5. Chen W, Wagner L, Boyd T, Nagarajan R, Dasgupta R. Extralobar pulmonary sequestration presenting with torsion: a case report and review of literature. J Pediatr Surg. 2011 Oct; 46(10):2025-8. PMID: 22008345.
    View in: PubMed
  6. Fouladi M, Stewart CF, Olson J, Wagner LM, Onar-Thomas A, Kocak M, Packer RJ, Goldman S, Gururangan S, Gajjar A, Demuth T, Kun LE, Boyett JM, Gilbertson RJ. Phase I trial of MK-0752 in children with refractory CNS malignancies: a pediatric brain tumor consortium study. J Clin Oncol. 2011 Sep 10; 29(26):3529-34. PMID: 21825264.
    View in: PubMed
  7. Myers K, Davies SM, Harris RE, Spunt SL, Smolarek T, Zimmerman S, McMasters R, Wagner L, Mueller R, Auerbach AD, Mehta PA. The clinical phenotype of children with Fanconi anemia caused by biallelic FANCD1/BRCA2 mutations. Pediatr Blood Cancer. 2012 Mar; 58(3):462-5. PMID: 21548014.
    View in: PubMed
  8. Wagner LM, Gelfand MJ, Laor T, Ryckman FC, Al-Ghawi H, Bove KE. A welcome surprise: nodular fasciitis presenting as soft tissue sarcoma. J Pediatr Hematol Oncol. 2011 May; 33(4):316-9. PMID: 20975584.
    View in: PubMed
  9. Wagner L. Camptothecin-based regimens for treatment of ewing sarcoma: past studies and future directions. Sarcoma. 2011; 2011:957957. PMID: 21512587.
    View in: PubMed
  10. Fernandez KS, Baum R, Fung B, Yeager N, Leonis MA, Wagner LM, Tiao G, Ross ME. Chemoresistant hepatoblastoma in a patient with mosaic trisomy 18 treated with orthotopic liver transplantation. Pediatr Blood Cancer. 2011 Mar; 56(3):498-500. PMID: 21113936.
    View in: PubMed
  11. Weiss BD, Dasgupta R, Gelfand MJ, Laor T, Yin H, Breneman JC, Lavigne R, Elluru RG, Wagner LM. Use of sentinel node biopsy for staging parameningeal rhabdomyosarcoma. Pediatr Blood Cancer. 2011 Sep; 57(3):520-3. PMID: 21744475.
    View in: PubMed
  12. Bagatell R, London WB, Wagner LM, Voss SD, Stewart CF, Maris JM, Kretschmar C, Cohn SL. Phase II study of irinotecan and temozolomide in children with relapsed or refractory neuroblastoma: a Children's Oncology Group study. J Clin Oncol. 2011 Jan 10; 29(2):208-13. PMID: 21115869.
    View in: PubMed
  13. Wagner LM. Oral irinotecan for treatment of pediatric solid tumors: ready for prime time? Pediatr Blood Cancer. 2010 May; 54(5):661-2. PMID: 20108333.
    View in: PubMed
  14. Wagner LM, Perentesis JP, Reid JM, Ames MM, Safgren SL, Nelson MD, Ingle AM, Blaney SM, Adamson PC. Phase I trial of two schedules of vincristine, oral irinotecan, and temozolomide (VOIT) for children with relapsed or refractory solid tumors: a Children's Oncology Group phase I consortium study. Pediatr Blood Cancer. 2010 Apr; 54(4):538-45. PMID: 20049936.
    View in: PubMed
  15. Wagner LM, Danks MK. New therapeutic targets for the treatment of high-risk neuroblastoma. J Cell Biochem. 2009 May 1; 107(1):46-57. PMID: 19277986.
    View in: PubMed
  16. Wagner LM, Villablanca JG, Stewart CF, Crews KR, Groshen S, Reynolds CP, Park JR, Maris JM, Hawkins RA, Daldrup-Link HE, Jackson HA, Matthay KK. Phase I trial of oral irinotecan and temozolomide for children with relapsed high-risk neuroblastoma: a new approach to neuroblastoma therapy consortium study. J Clin Oncol. 2009 Mar 10; 27(8):1290-6. PMID: 19171709.
    View in: PubMed
  17. Wagner LM, Crews KR, Stewart CF, Rodriguez-Galindo C, McNall-Knapp RY, Albritton K, Pappo AS, Furman WL. Reducing irinotecan-associated diarrhea in children. Pediatr Blood Cancer. 2008 Feb; 50(2):201-7. PMID: 17570704.
    View in: PubMed
  18. Wagner LM, McLendon RE, Yoon KJ, Weiss BD, Billups CA, Danks MK. Targeting methylguanine-DNA methyltransferase in the treatment of neuroblastoma. Clin Cancer Res. 2007 Sep 15; 13(18 Pt 1):5418-25. PMID: 17875772.
    View in: PubMed
  19. Wagner LM, Garrett JK, Ballard ET, Hill DA, Perry A, Biegel JA, Collins MH. Malignant rhabdoid tumor mimicking hepatoblastoma: a case report and literature review. Pediatr Dev Pathol. 2007 Sep-Oct; 10(5):409-15. PMID: 17929989.
    View in: PubMed
  20. Will E, Bailey J, Schuesler T, Modlich U, Balcik B, Burzynski B, Witte D, Layh-Schmitt G, Rudolph C, Schlegelberger B, von Kalle C, Baum C, Sorrentino BP, Wagner LM, Kelly P, Reeves L, Williams DA. Importance of murine study design for testing toxicity of retroviral vectors in support of phase I trials. Mol Ther. 2007 Apr; 15(4):782-91. PMID: 17299409.
    View in: PubMed
  21. Wagner LM, McAllister N, Goldsby RE, Rausen AR, McNall-Knapp RY, McCarville MB, Albritton K. Temozolomide and intravenous irinotecan for treatment of advanced Ewing sarcoma. Pediatr Blood Cancer. 2007 Feb; 48(2):132-9. PMID: 16317751.
    View in: PubMed
  22. Wagner LM, Burger RA, Guichard SM, Raimondi SC, Santana VM, Furman WL, Barnette P, Danks MK. Pilot study to evaluate MYCN expression as a neuroblastoma cell marker to detect minimal residual disease by RT-PCR. J Pediatr Hematol Oncol. 2006 Oct; 28(10):635-41. PMID: 17023822.
    View in: PubMed
  23. Wagner LM, Billups CA, Furman WL, Rao BN, Santana VM. Combined use of erythropoietin and granulocyte colony-stimulating factor does not decrease blood transfusion requirements during induction therapy for high-risk neuroblastoma: a randomized controlled trial. J Clin Oncol. 2004 May 15; 22(10):1886-93. PMID: 15143081.
    View in: PubMed
  24. Wagner LM, Crews KR, Iacono LC, Houghton PJ, Fuller CE, McCarville MB, Goldsby RE, Albritton K, Stewart CF, Santana VM. Phase I trial of temozolomide and protracted irinotecan in pediatric patients with refractory solid tumors. Clin Cancer Res. 2004 Feb 1; 10(3):840-8. PMID: 14871959.
    View in: PubMed
  25. Wagner LM, Zhou H, Brockmeyer DL, Hedlund GL. Spinal cord schwannomas mimicking drop metastases in a patient with intramedullary ependymoma and neurofibromatosis 2. J Pediatr Hematol Oncol. 2004 Jan; 26(1):56-9. PMID: 14707716.
    View in: PubMed
  26. Wagner L, Scaife E, White KS, Zhou H. Fetus in fetu: unexpected cause of an abdominal mass. J Pediatr Hematol Oncol. 2002 Dec; 24(9):779-80. PMID: 12468926.
    View in: PubMed
  27. Goldsby R, Pulsipher M, Adams R, Coffin C, Albritton K, Wagner L. Unexpected pleural effusions in 3 pediatric patients treated with STI-571. J Pediatr Hematol Oncol. 2002 Nov; 24(8):694-5. PMID: 12439048.
    View in: PubMed
  28. Wagner LM, Guichard SM, Burger RA, Morton CL, Straign CM, Ashmun RA, Harris LC, Houghton PJ, Potter PM, Danks MK. Efficacy and toxicity of a virus-directed enzyme prodrug therapy purging method: preclinical assessment and application to bone marrow samples from neuroblastoma patients. Cancer Res. 2002 Sep 1; 62(17):5001-7. PMID: 12208753.
    View in: PubMed
  29. Wagner L, Hill DA, Fuller C, Pedrosa M, Bhakta M, Perry A, Dome JS. Treatment of metastatic rhabdoid tumor of the kidney. J Pediatr Hematol Oncol. 2002 Jun-Jul; 24(5):385-8. PMID: 12142788.
    View in: PubMed
  30. Wagner LM, Neel MD, Pappo AS, Merchant TE, Poquette CA, Rao BN, Rodriguez-Galindo C. Fractures in pediatric Ewing sarcoma. J Pediatr Hematol Oncol. 2001 Dec; 23(9):568-71. PMID: 11902298.
    View in: PubMed
  31. Meck MM, Wierdl M, Wagner LM, Burger RA, Guichard SM, Krull EJ, Harris LC, Potter PM, Danks MK. A virus-directed enzyme prodrug therapy approach to purging neuroblastoma cells from hematopoietic cells using adenovirus encoding rabbit carboxylesterase and CPT-11. Cancer Res. 2001 Jul 1; 61(13):5083-9. PMID: 11431345.
    View in: PubMed
  32. Wagner LM, Furman WL. Haemopoietic growth factors in paediatric oncology: a review of the literature. Paediatr Drugs. 2001; 3(3):195-217. PMID: 11310717.
    View in: PubMed