Khaled M. Ziada, MD

Director, Cardiac Catheterization Laboratories
Director, Interventional Services
Director, Cardiovascular Interventional Fellowship Program

Clinical interests

  • Angioplasty
  • Cardiovascular Disease
  • Carotid Interventions
  • Coronary Physiology
  • Interventional Cardiology
  • Intravascular Ultrasound
  • Peripheral Interventions

Khaled M. Ziada, MD

Director, Cardiac Catheterization Laboratories
Director, Interventional Services
Director, Cardiovascular Interventional Fellowship Program

Biography

My name is Khaled Ziada; I received my medical degree from Cairo University, School of Medicine, Egypt. I completed internal medicine residency and general cardiovascular medicine fellowship at the Cleveland Clinic Foundation. I stayed at the Cleveland Clinic for interventional fellowship training in cardiac and vascular interventions as well as a research fellowship in intravascular ultrasound.

I am board certified by the American Board of Internal Medicine in Internal Medicine, Cardiovascular Diseases and Interventional Cardiology.

Faculty rank

Professor of Medicine
Gill Foundation Professor of Interventional Cardiology

Education

Degree
Cairo University, School of Medicine, Cairo, Egypt

Residency
Cleveland Clinic Foundation
Cairo University Hospital, Egypt

Fellowship
Cardiovascular Medicine, Cleveland Clinic Foundation
Interventional Cardiology, Cleveland Clinic Foundation
Research, Intravascular Ultrasound, Cleveland Clinic Foundation

Certifications or Special training
American Board of Internal Medicine
American Board of Internal Medicine, Cardiovascular Disease
American Board of Internal Medicine, Interventional Cardiology

Cardiac Catheterization

UK Albert B. Chandler Hospital - Pavilion G
Gill Heart Institute
1000 S. Limestone
Lexington KY 40536-0602


UK HealthCare accepts many forms of insurance. See list of insurers »

 
  1. Wallace EL, Tasan E, Cook BS, Charnigo R, Abdel-Latif AK, Ziada KM. Long-Term Outcomes and Causes of Death in Patients With Renovascular Disease Undergoing Renal Artery Stenting. Angiology. 2016 Aug;67(7):657-63.
    View in: PubMed
  2. Sexton TR, Wallace EL, Chen A, Charnigo RJ, Reda HK, Ziada KM, Gurley JC, Smyth SS. Thromboinflammatory response and predictors of outcomes in patients undergoing transcatheter aortic valve replacement. J Thromb Thrombolysis. 2016 Apr;41(3):384-93.
    View in: PubMed
  3. Ziada KM, Abdel-Latif A, Charnigo R, Moliterno DJ. Safety of an abbreviated duration of dual antiplatelet therapy (≤6 months) following second-generation drug-eluting stents for coronary artery disease: A systematic review and meta-analysis of randomized trials. Catheter Cardiovasc Interv. 2016 Mar;87(4):722-32.
    View in: PubMed
  4. Ruiz-Rodriguez E, Asfour A, Lolay G, Ziada KM, Abdel-Latif AK. Systematic Review and Meta-Analysis of Major Cardiovascular Outcomes for Radial Versus Femoral Access in Patients With Acute Coronary Syndrome. South Med J. 2016 Jan;109(1):61-76.
    View in: PubMed
  5. Déry JP, Mahaffey KW, Tricoci P, White HD, Podder M, Westerhout CM, Moliterno DJ, Harrington RA, Chen E, Strony J, Van de Werf F, Ziada KM, Held C, Aylward PE, Armstrong PW, Rao SV. Arterial access site and outcomes in patients undergoing percutaneous coronary intervention with and without vorapaxar. Catheter Cardiovasc Interv. 2015 Dec 23.
    View in: PubMed
  6. Wallace EL, Abdel-Latif A, Charnigo R, Moliterno DJ, Brodie B, Matnani R, Ziada KM. Meta-analysis of long-term outcomes for drug-eluting stents versus bare-metal stents in primary percutaneous coronary interventions for ST-segment elevation myocardial infarction. Am J Cardiol. 2012 Apr 1; 109(7):932-40. PMID: 22221949.
    View in: PubMed
  7. Cummings MS, Kuo BT, Ziada KM. A rare anomaly of the aortic arch: aberrant right subclavian artery associated with common carotid trunk. J Invasive Cardiol. 2011 Oct; 23(10):E241-3. PMID: 21972170.
    View in: PubMed
  8. Ziada KM, Charnigo R, Moliterno DJ. Long-term follow-up of drug-eluting stents placed in the setting of ST-segment elevation myocardial infarction. JACC Cardiovasc Interv. 2011 Jan; 4(1):39-41. PMID: 21251627.
    View in: PubMed
  9. Abdel-Latif A, Mukherjee D, Mesgarzadeh P, Ziada KM. Drug-eluting stents in patients with end-stage renal disease: meta-analysis and systematic review of the literature. Catheter Cardiovasc Interv. 2010 Dec 1; 76(7):942-8. PMID: 20506492.
    View in: PubMed
  10. Wiisanen ME, Abdel-Latif A, Mukherjee D, Ziada KM. Drug-eluting stents versus bare-metal stents in saphenous vein graft interventions: a systematic review and meta-analysis. JACC Cardiovasc Interv. 2010 Dec; 3(12):1262-73. PMID: 21232720.
    View in: PubMed
  11. Abdel-Latif A, Zuba-Surma EK, Ziada KM, Kucia M, Cohen DA, Kaplan AM, Van Zant G, Selim S, Smyth SS, Ratajczak MZ. Evidence of mobilization of pluripotent stem cells into peripheral blood of patients with myocardial ischemia. Exp Hematol. 2010 Dec; 38(12):1131-1142.e1. PMID: 20800644.
    View in: PubMed
  12. Macaulay TE, Allen C, Ziada KM. Thrombin receptor antagonism -the potential of antiplatelet medication SCH 530348. Expert Opin Pharmacother. 2010 Apr; 11(6):1015-22. PMID: 20307225.
    View in: PubMed
  13. Ziada KM, Abdel-Latif A. Drug-eluting stents in patients with ESRD on dialysis: a small step forward. Am J Kidney Dis. 2009 Aug; 54(2):197-200. PMID: 19619843.
    View in: PubMed
  14. Becker RC, Moliterno DJ, Jennings LK, Pieper KS, Pei J, Niederman A, Ziada KM, Berman G, Strony J, Joseph D, Mahaffey KW, Van de Werf F, Veltri E, Harrington RA. Safety and tolerability of SCH 530348 in patients undergoing non-urgent percutaneous coronary intervention: a randomised, double-blind, placebo-controlled phase II study. Lancet. 2009 Mar 14; 373(9667):919-28. PMID: 19286091.
    View in: PubMed
  15. Moliterno DJ, Ziada KM. The safety and efficacy of glycoprotein IIb/IIIa inhibitors for primary angioplasty: more options to choose and more time to decide. J Am Coll Cardiol. 2008 Feb 5; 51(5):536-7. PMID: 18237681.
    View in: PubMed
  16. Weathers LW, Ziada KM. Drug-eluting stents in patients with end-stage renal disease. Minerva Cardioangiol. 2008 Feb; 56(1):117-25. PMID: 18432174.
    View in: PubMed
  17. Ziada KM. Coronary revascularization in end-stage renal disease. Curr Cardiol Rep. 2007 Sep; 9(5):389-95. PMID: 17877934.
    View in: PubMed
  18. Das P, Moliterno DJ, Charnigo R, Mukherjee D, Steinhubl SR, Sneed JD, Booth DC, Ziada KM. Impact of drug-eluting stents on outcomes of patients with end-stage renal disease undergoing percutaneous coronary revascularization. J Invasive Cardiol. 2006 Sep; 18(9):405-8. PMID: 16954577.
    View in: PubMed
  19. Das P, Ziada K, Steinhubl SR, Moliterno DJ, Hamdalla H, Jozic J, Mukherjee D. Heparin-induced thrombocytopenia and cardiovascular diseases. Am Heart J. 2006 Jul; 152(1):19-26. PMID: 16824828.
    View in: PubMed
  20. Gurm HS, Breitbart Y, Vivekanathan D, Yen MH, Fathi R, Ziada KM, Whitlow PL, Ellis SG. Preprocedural statin use is associated with a reduced hazard of postprocedural myonecrosis in patients undergoing rotational atherectomy--a propensity-adjusted analysis. Am Heart J. 2006 May; 151(5):1031.e1-6. PMID: 16644330.
    View in: PubMed
  21. Ellis K, Ziada KM, Vivekananthan D, Latif AA, Shaaraoui M, Martin D, Grimm RA. Transthoracic echocardiographic predictors of left atrial appendage thrombus. Am J Cardiol. 2006 Feb 1; 97(3):421-5. PMID: 16442409.
    View in: PubMed
  22. Ziada KM, Yadav JS, Mukherjee D, Lauer MS, Bhatt DL, Kapadia S, Roffi M, Vora N, Tiong I, Bajzer C. Comparison of results of carotid stenting followed by open heart surgery versus combined carotid endarterectomy and open heart surgery (coronary bypass with or without another procedure). Am J Cardiol. 2005 Aug 15; 96(4):519-23. PMID: 16098304.
    View in: PubMed
  23. Tuzcu EM, Kapadia SR, Sachar R, Ziada KM, Crowe TD, Feng J, Magyar WA, Hobbs RE, Starling RC, Young JB, McCarthy P, Nissen SE. Intravascular ultrasound evidence of angiographically silent progression in coronary atherosclerosis predicts long-term morbidity and mortality after cardiac transplantation. J Am Coll Cardiol. 2005 May 3; 45(9):1538-42. PMID: 15862431.
    View in: PubMed
  24. Mukherjee D, Topol EJ, Moliterno DJ, Brennan DM, Ziada K, Cho L, Steinhubl SR. Extracardiac vascular disease and effectiveness of sustained clopidogrel treatment. Heart. 2006 Jan; 92(1):49-51. PMID: 15845611.
    View in: PubMed
  25. Khan MN, Joseph G, Khaykin Y, Ziada KM, Wilkoff BL. Delayed lead perforation: a disturbing trend. Pacing Clin Electrophysiol. 2005 Mar; 28(3):251-3. PMID: 15733190.
    View in: PubMed
  26. Chiu JH, Bhatt DL, Ziada KM, Chew DP, Whitlow PL, Lincoff AM, Ellis SG, Topol EJ. Impact of female sex on outcome after percutaneous coronary intervention. Am Heart J. 2004 Dec; 148(6):998-1002. PMID: 15632884.
    View in: PubMed
  27. Wazni OM, Martin DO, Marrouche NF, Latif AA, Ziada K, Shaaraoui M, Almahameed S, Schweikert RA, Saliba WI, Gillinov AM, Tang WH, Mills RM, Francis GS, Young JB, Natale A. Plasma B-type natriuretic peptide levels predict postoperative atrial fibrillation in patients undergoing cardiac surgery. Circulation. 2004 Jul 13; 110(2):124-7. PMID: 15210589.
    View in: PubMed
  28. Chen MS, Bhatt DL, Mukherjee D, Chan AW, Roffi M, Kapadia SR, Ziada KM, Chew DP, Bajzer CT, Yadav JS. Feasibility of simultaneous bilateral carotid artery stenting. Catheter Cardiovasc Interv. 2004 Apr; 61(4):437-42. PMID: 15065133.
    View in: PubMed
  29. Schoenhagen P, Stone GW, Nissen SE, Grines CL, Griffin J, Clemson BS, Vince DG, Ziada K, Crowe T, Apperson-Hanson C, Kapadia SR, Tuzcu EM. Coronary plaque morphology and frequency of ulceration distant from culprit lesions in patients with unstable and stable presentation. Arterioscler Thromb Vasc Biol. 2003 Oct 1; 23(10):1895-900. PMID: 12842842.
    View in: PubMed
  30. Yadav JS, Ziada KM, Almany S, Davis TP, Castaneda F. Comparison of the QuickSeal Femoral Arterial Closure System with manual compression following diagnostic and interventional catheterization procedures. Am J Cardiol. 2003 Jun 15; 91(12):1463-6, A6. PMID: 12804735.
    View in: PubMed
  31. Ramasubbu K, Schoenhagen P, Balghith MA, Brechtken J, Ziada KM, Kapadia SR, Hobbs RE, Rincon G, Nissen SE, Tuzcu EM. Repeated intravascular ultrasound imaging in cardiac transplant recipients does not accelerate transplant coronary artery disease. J Am Coll Cardiol. 2003 May 21; 41(10):1739-43. PMID: 12767657.
    View in: PubMed
  32. Berkalp B, Badak O, Schoenhagen P, Ziada KM, Whitlow PL, Nissen SE, Tuzcu EM. Influence of various percutaneous coronary interventional devices on postinterventional luminal shape and plaque surface characteristics as determined by intravascular ultrasound. Am J Cardiol. 2003 May 15; 91(10):1269-72. PMID: 12745119.
    View in: PubMed
  33. Tsutsui H, Schoenhagen P, Ziada KM, Crowe TD, Klingensmith JD, Vince DG, Bott-Silverman C, Starling R, Hobbs RE, Young J, Nissen SE, Tuzcu EM. Early constriction or expansion of the external elastic membrane area determines the late remodeling response and cumulative lumen loss in transplant vasculopathy: an intravascular ultrasound study with 4-year follow-up. J Heart Lung Transplant. 2003 May; 22(5):519-25. PMID: 12742413.
    View in: PubMed
  34. Cura FA, Kapadia SR, L'Allier PL, Ziada KM, Mukherjee D, Wolski KE, Yadav JS, Brener SJ, Whitlow PL, Topol EJ, Ellis SG. Effect of uncoated stenting versus balloon angioplasty alone of long coronary (>20 mm) versus shorter narrowings on one-year event-free survival. Am J Cardiol. 2003 Mar 1; 91(5):587-90. PMID: 12615267.
    View in: PubMed
  35. Roffi M, Mukherjee D, Chew DP, Bhatt DL, Cho L, Robbins MA, Ziada KM, Brennan DM, Ellis SG, Topol EJ. Lack of benefit from intravenous platelet glycoprotein IIb/IIIa receptor inhibition as adjunctive treatment for percutaneous interventions of aortocoronary bypass grafts: a pooled analysis of five randomized clinical trials. Circulation. 2002 Dec 10; 106(24):3063-7. PMID: 12473552.
    View in: PubMed
  36. Iyisoy A, Ziada K, Schoenhagen P, Tsutsui H, Kapadia S, Popovich J, Rincon G, Nissen SE, Tuzcu EM. Intravascular ultrasound evidence of ostial narrowing in nonatherosclerotic left main coronary arteries. Am J Cardiol. 2002 Oct 1; 90(7):773-5. PMID: 12356397.
    View in: PubMed
  37. Schoenhagen P, Vince DG, Ziada KM, Kapadia SR, Lauer MA, Crowe TD, Nissen SE, Tuzcu EM. Relation of matrix-metalloproteinase 3 found in coronary lesion samples retrieved by directional coronary atherectomy to intravascular ultrasound observations on coronary remodeling. Am J Cardiol. 2002 Jun 15; 89(12):1354-9. PMID: 12062727.
    View in: PubMed
  38. Jeremias A, Albirini A, Ziada KM, Chew DP, Brener SJ, Topol EJ, Ellis SG. Prognostic significance of creatine kinase-MB elevation after percutaneous coronary intervention in patients with chronic renal dysfunction. Am Heart J. 2002 Jun; 143(6):1040-5. PMID: 12075261.
    View in: PubMed
  39. Jeremias A, Bhatt DL, Chew DP, Ziada KM, Albirini A, Brener SJ, Lincoff AM, Topol EJ, Ellis SG. Safety of abciximab during percutaneous coronary intervention in patients with chronic renal insufficiency. Am J Cardiol. 2002 May 15; 89(10):1209-11. PMID: 12008179.
    View in: PubMed
  40. Casserly IP, Ziada K, Kapadia S, Schoenhagen P, Tsutsui H, Karafa M, Shah A, Popovich J, Nissen SE, Tuzcu EM. Impact of nonmeasurable borders and variation in cross-section counts on intravascular ultrasound measurement of atherosclerotic plaque volume. Am J Cardiol. 2002 Jan 15; 89(2):169-73. PMID: 11792337.
    View in: PubMed
  41. Bhatt DL, Kapadia SR, Bajzer CT, Chew DP, Ziada KM, Mukherjee D, Roffi M, Topol EJ, Yadav JS. Dual antiplatelet therapy with clopidogrel and aspirin after carotid artery stenting. J Invasive Cardiol. 2001 Dec; 13(12):767-71. PMID: 11731685.
    View in: PubMed
  42. Mukherjee D, Kalahasti V, Roffi M, Bhatt DL, Kapadia SR, Bajzer C, Reginelli J, Ziada KM, Hughes K, Yadav JS. Self-expanding stents for carotid interventions: comparison of nitinol versus stainless-steel stents. J Invasive Cardiol. 2001 Nov; 13(11):732-5. PMID: 11689714.
    View in: PubMed
  43. Schoenhagen P, Vince DG, Ziada KM, Tsutsui H, Jeremias A, Crowe TD, Nissen SE, Tuzcu EM. Association of arterial expansion (expansive remodeling) of bifurcation lesions determined by intravascular ultrasonography with unstable clinical presentation. Am J Cardiol. 2001 Oct 1; 88(7):785-7. PMID: 11589850.
    View in: PubMed
  44. Kapadia SR, Bajzer CT, Ziada KM, Bhatt DL, Wazni OM, Silver MJ, Beven EG, Ouriel K, Yadav JS. Initial experience of platelet glycoprotein IIb/IIIa inhibition with abciximab during carotid stenting: a safe and effective adjunctive therapy. Stroke. 2001 Oct; 32(10):2328-32. PMID: 11588321.
    View in: PubMed
  45. Tsutsui H, Ziada KM, Schoenhagen P, Iyisoy A, Magyar WA, Crowe TD, Klingensmith JD, Vince DG, Rincon G, Hobbs RE, Yamagishi M, Nissen SE, Tuzcu EM. Lumen loss in transplant coronary artery disease is a biphasic process involving early intimal thickening and late constrictive remodeling: results from a 5-year serial intravascular ultrasound study. Circulation. 2001 Aug 7; 104(6):653-7. PMID: 11489770.
    View in: PubMed
  46. Schoenhagen P, Ziada KM, Vince DG, Nissen SE, Tuzcu EM. Arterial remodeling and coronary artery disease: the concept of "dilated" versus "obstructive" coronary atherosclerosis. J Am Coll Cardiol. 2001 Aug; 38(2):297-306. PMID: 11499716.
    View in: PubMed
  47. Kapadia SR, Nissen SE, Ziada KM, Rincon G, Crowe TD, Boparai N, Young JB, Tuzcu EM. Impact of lipid abnormalities in development and progression of transplant coronary disease: a serial intravascular ultrasound study. J Am Coll Cardiol. 2001 Jul; 38(1):206-13. PMID: 11451276.
    View in: PubMed
  48. Tuzcu EM, Kapadia SR, Tutar E, Ziada KM, Hobbs RE, McCarthy PM, Young JB, Nissen SE. High prevalence of coronary atherosclerosis in asymptomatic teenagers and young adults: evidence from intravascular ultrasound. Circulation. 2001 Jun 5; 103(22):2705-10. PMID: 11390341.
    View in: PubMed
  49. Ziada KM, Roffi M, Crowe TD, Tuzcu EM. Adventitial hematoma triggering coronary spasm during percutaneous coronary intervention. J Invasive Cardiol. 2001 Jun; 13(6):464-6. PMID: 11385172.
    View in: PubMed
  50. Ziada KM, Kapadia SR, Belli G, Houghtaling PL, De Franco AC, Ellis SG, Whitlow PL, Franco I, Nissen SE, Tuzcu EM. Prognostic value of absolute versus relative measures of the procedural result after successful coronary stenting: importance of vessel size in predicting long-term freedom from target vessel revascularization. Am Heart J. 2001 May; 141(5):823-31. PMID: 11320373.
    View in: PubMed
  51. Mukherjee D, Roffi M, Kapadia SR, Bhatt DL, Bajzer C, Ziada KM, Kalahasti V, Hughes K, Yadav JS. Percutaneous intervention for symptomatic vertebral artery stenosis using coronary stents. J Invasive Cardiol. 2001 May; 13(5):363-6. PMID: 11385149.
    View in: PubMed
  52. Ziada KM, Roffi M, Yadav JS. Percutaneous stenting of a vertebral artery supplying the entire brain. Circulation. 2001 Mar 20; 103(11):E61. PMID: 11257093.
    View in: PubMed
  53. Cura FA, Bhatt DL, Lincoff AM, Kapadia SR, L'Allier PL, Ziada KM, Wolski KE, Moliterno DJ, Brener SJ, Ellis SG, Topol EJ. Pronounced benefit of coronary stenting and adjunctive platelet glycoprotein IIb/IIIa inhibition in complex atherosclerotic lesions. Circulation. 2000 Jul 4; 102(1):28-34. PMID: 10880411.
    View in: PubMed
  54. Schoenhagen P, Ziada KM, Kapadia SR, Crowe TD, Nissen SE, Tuzcu EM. Extent and direction of arterial remodeling in stable versus unstable coronary syndromes : an intravascular ultrasound study. Circulation. 2000 Feb 15; 101(6):598-603. PMID: 10673250.
    View in: PubMed
  55. Kapadia SR, Ziada KM, L'Allier PL, Crowe TD, Rincon G, Hobbs RE, Bott-Silverman C, Young JB, Nissen SE, Tuzcu EM. Intravascular ultrasound imaging after cardiac transplantation: advantage of multi-vessel imaging. J Heart Lung Transplant. 2000 Feb; 19(2):167-72. PMID: 10703693.
    View in: PubMed
  56. Ziada KM, Kapadia SR, Tuzcu EM, Nissen SE. The current status of intravascular ultrasound imaging. Curr Probl Cardiol. 1999 Sep; 24(9):541-66. PMID: 10480047.
    View in: PubMed
  57. Ziada KM, Tuzcu EM, Nissen SE. Application of intravascular ultrasound imaging in understanding and guiding percutaneous therapy for atherosclerotic coronary disease. Cardiol Rev. 1999 Sep-Oct; 7(5):289-300. PMID: 11208240.
    View in: PubMed
  58. Kapadia SR, Nissen SE, Ziada KM, Guetta V, Crowe TD, Hobbs RE, Starling RC, Young JB, Tuzcu EM. Development of transplantation vasculopathy and progression of donor-transmitted atherosclerosis: comparison by serial intravascular ultrasound imaging. Circulation. 1998 Dec 15; 98(24):2672-8. PMID: 9851952.
    View in: PubMed
  59. Ziada KM, Tuzcu EM, De Franco AC, Kim MH, Raymond RE, Franco I, Whitlow PL, Ellis SG, Nissen SE. Intravascular ultrasound assessment of the prevalence and causes of angiographic "haziness" following high-pressure coronary stenting. Am J Cardiol. 1997 Jul 15; 80(2):116-21. PMID: 9230144.
    View in: PubMed