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Heidi L. Weiss, PhD

Cancer Center Member

Markey Research Programs:
    Drug Discovery, Delivery and Translational Therapeutics

Associate Director, Shared Resources and Director, Biostatistics Shared Resource Facility

Professor

Department of Surgery ›
College of Medicine ›

Research Focus

Design and analysis of early phase clinical trials focusing on Bayesian design and interim monitoring. Statistical analysis of transgenic, xenograft and chemically induced mouse models of cancer.

Contact Information

800 Rose Street
CC448 Roach Building
University of Kentucky
Lexington Kentucky 40536

Key Publications

  1. Massarweh S, Tham YL, Huang J, Sexton K, Weiss H, Tsimelzon A, Beyer A, Rimawi M, Cai WY, Hilsenbeck S, Fuqua S and Elledge R. A phase II neoadjuvant trial of anastrozole, fulvestrant, and gefitinib in patients with newly diagnosed estrogen receptor positive breast cancer. Breast Cancer Res Treat 129:819-27, 2011.
  2. Weiss HL, Urban DA, Grizzle WE, Cronin KA, Freedman LS, Kelloff GJ, Lieberman R. Bayesian Monitoring of a phase II chemoprevention trial in high risk cohorts for prostate cancer. Urology 57(4A):220-223, 2001.

Recent Publications

(five most recent publications via an automated list from PubMed, based on researcher’s ID and the University of Kentucky)
  1. Stewart RL, Carpenter BL, West DS, Knifley T, Liu L, Wang C, Weiss HL, Gal TS, Durbin EB, Arnold SM, O'Connor KL, Chen M.
    S100A4 drives non-small cell lung cancer invasion, associates with poor prognosis, and is effectively targeted by the FDA-approved anti-helminthic agent niclosamide.
    Oncotarget. 2016 Apr 25.
  2. Stewart RL, West D, Wang C, Weiss HL, Gal T, Durbin E, O'Connor W, Chen M, O'Connor KL.
    Elevated integrin α6β4 expression is associated with venous invasion and decreased overall survival in non-small cell lung cancer.
    Hum Pathol. 2016 Apr 20.
  3. Li J, Song J, Weiss HL, Weiss T, Townsend CM, Evers BM.
    Activation of AMPK Stimulates Neurotensin Secretion in Neuroendocrine Cells.
    Mol Endocrinol. 2016 Jan;30(1):26-36.
  4. Wen YA, Li X, Goretsky T, Weiss HL, Barrett TA, Gao T.
    Loss of PHLPP protects against colitis by inhibiting intestinal epithelial cell apoptosis.
    Biochim Biophys Acta. 2015 Oct;1852(10 Pt A):2013-23.
  5. Kim JT, Li J, Song J, Lee EY, Weiss HL, Townsend CM, Evers BM.
    Differential expression and tumorigenic function of neurotensin receptor 1 in neuroendocrine tumor cells.
    Oncotarget. 2015 Sep 29;6(29):26960-70.